Oregano (Origanum vulgare L.) essential oil provides anti-inflammatory activity and facilitates wound healing in a human keratinocytes cell model

2020 ◽  
Vol 144 ◽  
pp. 111586 ◽  
Author(s):  
Rosanna Avola ◽  
Giuseppe Granata ◽  
Corrada Geraci ◽  
Edoardo Napoli ◽  
Adriana Carol Eleonora Graziano ◽  
...  
Keyword(s):  
Wound Healing ◽  
Essential Oil ◽  
Cell Model ◽  
Human Keratinocytes ◽  
Inflammatory Activity ◽  
Origanum Vulgare ◽  
Anti Inflammatory

scholarly journals Electrosprayed Chitin Nanofibril/Electrospun Polyhydroxyalkanoate Fiber Mesh as Functional Nonwoven for Skin Application

2020 ◽  
Vol 11 (3) ◽  
pp. 62 ◽  
Author(s):  
Bahareh Azimi ◽  
Lily Thomas ◽  
Alessandra Fusco ◽  
Ozlem Ipek Kalaoglu-Altan ◽  
Pooja Basnett ◽  
...  
Keyword(s):  
Wound Healing ◽  
Plant Biomass ◽  
Electrospun Fiber ◽  
Human Keratinocytes ◽  
Polymer Surfaces ◽  
Inflammatory Activity ◽  
Anti Inflammatory ◽  
Size And Morphology ◽  
Surface Modified

Polyhydroxyalkanoates (PHAs) are a family of bio-based polyesters that have found different biomedical applications. Chitin and lignin, byproducts of fishery and plant biomass, show antimicrobial and anti-inflammatory activity on the nanoscale. Due to their polarities, chitin nanofibril (CN) and nanolignin (NL) can be assembled into micro-complexes, which can be loaded with bioactive factors, such as the glycyrrhetinic acid (GA) and CN-NL/GA (CLA) complexes, and can be used to decorate polymer surfaces. This study aims to develop completely bio-based and bioactive meshes intended for wound healing. Poly(3-hydroxybutyrate)/Poly(3-hydroxyoctanoate-co-3-hydroxydecanoate), P(3HB)/P(3HO-co-3HD) was used to produce films and fiber meshes, to be surface-modified via electrospraying of CN or CLA to reach a uniform distribution. P(3HB)/P(3HO-co-3HD) fibers with desirable size and morphology were successfully prepared and functionalized with CN and CLA using electrospinning and tested in vitro with human keratinocytes. The presence of CN and CLA improved the indirect antimicrobial and anti-inflammatory activity of the electrospun fiber meshes by downregulating the expression of the most important pro-inflammatory cytokines and upregulating human defensin 2 expression. This natural and eco-sustainable mesh is promising in wound healing applications.

Anti-inflammatory activity of essential oil of an endemicThymus fontanesiiBoiss. & Reut. with chemotype carvacrol, and its healing capacity on gastric lesions

2017 ◽  
Vol 41 (3) ◽  
pp. e12359 ◽  
Author(s):  
Lilia Mouhi ◽  
Houria Moghrani ◽  
Noureddine Nasrallah ◽  
Abdeltif Amrane ◽  
Rachida Maachi
Keyword(s):  
Essential Oil ◽  
Inflammatory Activity ◽  
Gastric Lesions ◽  
Anti Inflammatory

scholarly journals Wound Healing and Anti-Inflammatory Activity of Methanolic Extract of Gmelina arborea and Hemigraphis colorata in Rats

2017 ◽  
Vol 6 (8) ◽  
pp. 3116-3122 ◽  
Author(s):  
Bhagyalakshmi Chengattu Prakashbabu ◽  
Deepthi Vijay ◽  
Saju George ◽  
Sameer Kodiyil ◽  
Suresh Narayanan Nair ◽  
...  
Keyword(s):  
Wound Healing ◽  
Methanolic Extract ◽  
Inflammatory Activity ◽  
Gmelina Arborea ◽  
Anti Inflammatory

scholarly journals Essential Oil of Myrtus communis Inhibits Inflammation in Rats by Reducing Serum IL-6 and TNF-α

2011 ◽  
Vol 6 (10) ◽  
pp. 1934578X1100601 ◽  
Author(s):  
Andrea Maxia ◽  
Maria Assunta Frau ◽  
Danilo Falconieri ◽  
Manvendra Singh Karchuli ◽  
Sanjay Kasture
Keyword(s):  
Essential Oil ◽  
Inflammatory Activity ◽  
Myrtus Communis ◽  
Ear Edema ◽  
Tnf Α ◽  
Cotton Pellet ◽  
Anti Inflammatory ◽  
Factor Α ◽  
Necrosis Factor ◽  
Serum Tumor Necrosis

The topical anti-inflammatory activity of the essential oil of Myrtus communis L. was studied using croton oil induced ear edema and myeloperoxidase (MPO) activity in mice, and cotton pellet induced granuloma, and serum tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in rats. On topical application, the oil exhibited a significant decrease in the ear edema as well as MPO activity. The oil also inhibited cotton pellet-induced granuloma and serum TNF-α and IL-6. It can be concluded that the essential oil of Myrtus communis reduces leukocyte migration to the damaged tissue and exhibits anti-inflammatory activity.

Anti-edematogenic and anti-inflammatory activity of the essential oil from Croton rhamnifolioides leaves and its major constituent 1,8-cineole (eucalyptol)

2017 ◽  
Vol 96 ◽  
pp. 384-395 ◽  
Author(s):  
Anita Oliveira Brito Pereira Bezerra Martins ◽  
Lindaiane Bezerra Rodrigues ◽  
Francisco Rafael Alves Santana Cesário ◽  
Maria Rayane Correia de Oliveira ◽  
Cicera Datiane Morais Tintino ◽  
...  
Keyword(s):  
Essential Oil ◽  
Inflammatory Activity ◽  
Major Constituent ◽  
Anti Inflammatory

scholarly journals The Essential Oil and Hydrolats from Myristica fragrans Seeds with Magnesium Aluminometasilicate as Excipient: Antioxidant, Antibacterial, and Anti-inflammatory Activity

Foods ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 37 ◽  
Author(s):  
Inga Matulyte ◽  
Aiste Jekabsone ◽  
Lina Jankauskaite ◽  
Paulina Zavistanaviciute ◽  
Vytaute Sakiene ◽  
...  
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Inflammatory Activity ◽  
Poly I:C ◽  
Bioactive Substances ◽  
Myristica Fragrans ◽  
Anti Inflammatory ◽  
Nutmeg Essential Oil

Nutmeg (Myristica fragrans) essential oil has antimicrobial, antiseptic, antiparasitic, anti-inflammatory, and antioxidant properties. We have recently demonstrated that hydrodistillation of nutmeg essential oil by applying magnesium aluminometasilicate as an excipient significantly increases both the content and amount of bioactive substances in the oil and hydrolats. In this study, we aimed to compare the antioxidant, antimicrobial, and anti-inflammatory activity of hydrolats and essential oil obtained by hydrodistillation in the presence and absence of magnesium aluminometasilicate as an excipient. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method revealed that magnesium aluminometasilicate did not significantly improved antioxidant activity of both essential oil and hydrolat. Antibacterial efficiency was evaluated by monitoring growth of 15 bacterial strains treated by a range of dilutions of the essential oil and the hydrolats. Essential oil with an excipient completely inhibited the growth of E. faecalis, S. mutans (referent), and P. multocida, whereas the pure oil was only efficient against the latter strain. Finally, the anti-inflammatory properties of the substances were assessed in a fibroblast cell culture treated with viral dsRNR mimetic Poly I:C. The essential oil with an excipient protected cells against Poly I:C-induced necrosis more efficiently compared to pure essential oil. Also, both the oil and the hydrolats with aluminometasilicate were more efficient in preventing IL-6 release in the presence of Poly I:C. Our results show that the use of magnesium aluminometasilicate as an excipient might change and in some cases improve the biological activities of nutmeg essential oil and hydrolats.

Sign in / Sign up

Export Citation Format

Share Document