scholarly journals Tumour necrosis factor alpha regulates iron transport and transporter expression in human intestinal epithelial cells

FEBS Letters ◽  
2004 ◽  
Vol 573 (1-3) ◽  
pp. 195-201 ◽  
Author(s):  
Deborah Johnson ◽  
Henry Bayele ◽  
Kelly Johnston ◽  
Jason Tennant ◽  
Surjit Kaila Srai ◽  
...  
Keyword(s):  
Tumour Necrosis ◽  
Iron Transport ◽  
Intestinal Epithelial Cells ◽  
Tumour Necrosis Factor Alpha ◽  
Intestinal Epithelial ◽  
Necrosis Factor Alpha ◽  
Human Intestinal Epithelial Cells ◽  
Factor Alpha ◽  
Transporter Expression ◽  
Necrosis Factor

scholarly journals Inhibition of the NF-κB Pathway in Human Intestinal Epithelial Cells by Commensal Streptococcus salivarius

2011 ◽  
Vol 77 (13) ◽  
pp. 4681-4684 ◽  
Author(s):  
Ghalia Kaci ◽  
Omar Lakhdari ◽  
Joël Doré ◽  
S. Dusko Ehrlich ◽  
Pierre Renault ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Intestinal Epithelial Cells ◽  
Intestinal Epithelial ◽  
Streptococcus Salivarius ◽  
Necrosis Factor Alpha ◽  
Content Type ◽  
Human Intestinal Epithelial Cells ◽  
Tnf Α ◽  
Factor Alpha ◽  
Necrosis Factor

ABSTRACTStreptococcus salivariusexhibited an anti-inflammatory effect on intestinal epithelial cells (IECs) and monocytes. Strains were screened using a reporter clone, HT-29/kB-luc-E, induced by tumor necrosis factor alpha (TNF-α). Supernatant from each strain downregulated NF-κB activation. The two most efficient strains produced an active metabolite (<3 kDa) which was able to downregulate the secretion of the proinflammatory chemokine interleukin-8 (IL-8).

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