Tracking the effect of oocyte dysmorphism due to trauma of oocyte retrieval on developmental potential of remaining oocyte pool and pregnancy outcome in intracytoplasmic sperm injection cycle (ICSI)

2013 ◽  
Vol 100 (3) ◽  
pp. S230
Author(s):  
S. Haseena ◽  
R. Chattopadhyay ◽  
A. Shukla ◽  
S.K. Goswami ◽  
M. Chakravarty ◽  
...  
Keyword(s):  
Pregnancy Outcome ◽  
Intracytoplasmic Sperm Injection ◽  
Oocyte Retrieval ◽  
Developmental Potential ◽  
Oocyte Dysmorphism ◽  
Injection Cycle

scholarly journals Early Serum Progesterone Measurement on 9th Day after Oocyte Retrieval can be used as a Predictor of Fresh Intracytoplasmic Sperm Injection Cycle Success

2022 ◽  
Vol 10 (B) ◽  
pp. 36-41
Author(s):  
Shereen Abdulhussien Kzar ◽  
Zainab Khafajy ◽  
Shatha Sadiq Al-Marayaty
Keyword(s):  
Pregnancy Rate ◽  
Intracytoplasmic Sperm Injection ◽  
Characteristic Curve ◽  
Area Under The Curve ◽  
Oocyte Retrieval ◽  
Fresh Embryo Transfer ◽  
Serum Progesterone ◽  
Iraqi Women ◽  
Predictor Of Success ◽  
Injection Cycle

BACKGROUND: In intracytoplasmic sperm injection (ICSI) infertility treatment cycles, measuring serum Progesterone level at day 9 after oocyte retrieval could be used as a predictor of success. METHODS: Sixty-nine women were prospectively included in this study, treated with fresh embryo transfer ICSI cycles. Progesterone analyses were performed on the day of oocyte pick up (day 0) at serum and follicular fluid, then re-assessment at serum on day 9 after oocyte retrieval. The data were compared to evaluate the correlation among hormones measured on day 0 and day 9 with pregnancy rate. RESULTS: Pregnancy rate of Iraqi women was 22% (n = 15), mean serum progesterone on day 9 among pregnant ladies was (mean ± SD, 39.5 ± 13.0) which was significantly higher than that who failed to get pregnant (mean 23.2 ± 11, p = 0.001), then after adjustment of the baseline readings (day 0) estimated mean = 11.1. The differences were still significant, receiver operating characteristic curve area showed that serum Progesterone on day 9 after pick up can differentiate correctly between those who will conceive and those who will not, with a sensitivity = 0.933 and specificity = 0.519, at cut off point = 22.33 and above, (Area under the curve = 0.822, p = 0.001). CONCLUSION: Serum progesterone on day 9 could be one of the predictors of endometrial receptivity and pregnancy, which is actually of great value for both doctors and patients during that stressful period till the date of confirmation, which might negatively affect treatment outcome, as well as the psychosocial and pharmacological impact of medication and limited activity for a failed one.

scholarly journals The effect of seasonality on reproductive outcome of patients undergoing intracytoplasmic sperm injection: A descriptive cross-sectional study

2020 ◽  
Author(s):  
Marzieh Mehrafza ◽  
Maryam Asgharnia ◽  
Azadeh Raoufi ◽  
Elmira Hosseinzadeh ◽  
Sajedeh Samadnia ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Pregnancy Outcome ◽  
Intracytoplasmic Sperm Injection ◽  
Cross Sectional Study ◽  
Reproductive Technology ◽  
Seasonal Effect ◽  
Medical Institute ◽  
Sectional Study ◽  
Cross Sectional ◽  
Injection Cycle

Background: There is conflicting evidence regarding the impact of season on the assisted reproductive technology outcome. Objective: To retrospectively compare three year outcome of women undergoing their first intracytoplasmic sperm injection cycle, across seasons. Materials and Methods: In this descriptive cross-sectional study, 3,670 women who underwent their first intracytoplasmic sperm injection cycle in Mehr Medical Institute, Rasht, Iran between April 2010 and May 2014 were studied. Women were divided into four groups according to the day of oocyte retrival as: spring (n = 808), summer (n = 994), autumn (n = 1066), and winter (n = 802). Basal and stimulation charecteristics were compared among groups. Results: While sperm concentration and motility were significantly lower during summer, the total number of retrieved and metaphase II oocytes were significantly higher (p = 0.0001, p = 0.0001, p = 0.004, p = 0.02, respectively). Fertilization rate were significantly higher during autumn (p = 0.0001). Also, the number of high- quality transferred embryos were significantly higher during summer and winter (p = 0.03). A similar pattern was observed in implantation rate and pregnancy over the four seasons Conclusion: Despite the fact that intracytoplasmic sperm injection minimize the seasonal effect on pregnancy outcome, changes in pregnancy rate still occur among different seasons without particular pattern. It seems that performing assisted reproductive technology procedures in a particular season should be considered as an effective factor. Key words: Intracytoplasmic sperm injection, Seasons, Pregnancy outcome.

scholarly journals Comparison of pregnancy outcome after intracytoplasmic sperm injection and in-vitro fertilization

1998 ◽  
Vol 13 (6) ◽  
pp. 1514-1518 ◽  
Author(s):  
I. Govaerts ◽  
F. Devreker ◽  
I. Koenig ◽  
I. Place ◽  
M. Van den Bergh ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Outcome ◽  
Intracytoplasmic Sperm Injection ◽  
Vitro Fertilization

scholarly journals Prognostic Factors of IVF&ICSI Cycle Cancellation in Patients with Endometriosis-Related Infertility

2020 ◽  
pp. 1-6
Author(s):  
Elif Külahci Aslan ◽  
Kiper Aslan ◽  
Cihan Cakir ◽  
Isil Kasapoglu ◽  
Berrin Avci ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Intracytoplasmic Sperm Injection ◽  
Systemic Disease ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Deep Infiltrating Endometriosis ◽  
Independent Factor ◽  
Group I ◽  
Cycle Cancellation ◽  
Injection Cycle

Objective: To elucidate the prognostic factors for intracytoplasmic sperm injection cycle cancellation in patients with endometriosis-related infertility. Study Design: This was a retrospective cohort study and conducted at the Assisted Reproductive Technology center of Uludag University School of Medicine, between the years 2011-2017. The electronic database was screened and infertile patients with endometriosis, without male factor infertility, systemic disease, or undefined adnexal mass, and aged <40 were selected. The endometriosis phenotype of all cycles was classified into three subgroups: superficial endometriosis, ovarian endometrioma and deep infiltrating endometriosis. Cycles were divided into two groups: Group I (Cycle Cancellation) vs. Group II (Embryo transferred). Results: Forty-four cycles were canceled and in 178 cycles, the embryo was able to be transferred. When the groups were compared age and day 3 FSH levels were statistically higher, and anti-Mullerian hormone and antral follicle count were statistically lower in Group I. The presence of adenomyosis was higher in Group I (64% vs. 40% p<0.01). The surgery rate with laparotomy was higher in Group I (54.5% vs. 13.5% p<0.01). Antral follicle count remained as the only independent factor associated with prognoses of the IVF cycle with binary logistic regression analysis. Cancellation rates were similar between the phenotypes of endometriosis. Conclusions: Poor ovarian reserve, advanced age, presence of adenomyosis, and history of laparotomy are negative prognostic factors associated with intracytoplasmic sperm injection cycle cancellation in endometriosis-related infertility. Antral follicle count is the only independent factor in predicting cycle cancellation. The phenotype of endometriosis does not affect the results.

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