Australeols A−F, neuroprotective meroterpenoids from Ganoderma australe

Fitoterapia ◽  
2019 ◽  
Vol 134 ◽  
pp. 250-255 ◽  
Author(s):  
Jiao-Jiao Zhang ◽  
Yun Dong ◽  
Fu-Ying Qin ◽  
Yong-Xian Cheng
Keyword(s):  
Ganoderma Australe

Optimization of biomass production with enhanced bioactive compound content by the medicinal mushroom Ganoderma australe under submerged culture

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
LM Papaspyridi ◽  
E Topakas ◽  
N Aligiannis ◽  
P Christakopoulos ◽  
AL Skaltsounis ◽  
...  
Keyword(s):  
Biomass Production ◽  
Submerged Culture ◽  
Bioactive Compound ◽  
Medicinal Mushroom ◽  
Ganoderma Australe

scholarly journals Criptógamos do Parque Estadual das Fontes do Ipiranga, São Paulo, SP, Brasil: Fungos, 10: Ganodermataceae

Hoehnea ◽  
2011 ◽  
Vol 38 (4) ◽  
pp. 687-696 ◽  
Author(s):  
Adriana de Mello Gugliotta ◽  
Grazielle Dias Poscolere ◽  
Thiago Vinicius Silva Campacci
Keyword(s):  
Sao Paulo ◽  
São Paulo ◽  
Ganoderma Australe

Foi realizado levantamento das espécies de Ganodermataceae que ocorrem no Parque Estadual das Fontes do Ipiranga (PEFI), Município de São Paulo, Estado de São Paulo, Brasil. Foram identificadas doze espécies: Amauroderma aurantiacum (Torrend) Gibertoni & Bernicchia, A. calcigenum (Berk.) Torrend, A. oblongisporum J.S. Furtado, A. pseudoboletus (Speg.) J.S. Furtado, A. rude (Berk.) Torrend, A. schomburgkii (Mont. & Berk.) Torrend, A. sprucei (Pat.) Torrend, Ganoderma australe (Fr.) Pat., G. multiplicatum (Mont.) Pat., G. orbiforme (Fr.) Ryvarden, G. perzonatum Murrill, G. zonatum Murrill. Ganoderma perzonatum e G. zonatum constituem novas citações para o Estado de São Paulo. São apresentados comentários para cada táxon estudado, bem como descrições e figuras de estruturas microscópicas das espécies que constituem novos registros. Chave de identificação das espécies ocorrentes no Parque também é apresentada.

Lanostane triterpenoids from cultivated fruiting bodies of the basidiomycete Ganoderma australe

2017 ◽  
Vol 32 (9) ◽  
pp. 1044-1049 ◽  
Author(s):  
Masahiko Isaka ◽  
Panida Chinthanom ◽  
Sermsiri Mayteeworakoon ◽  
Kobkul Laoteng ◽  
Wilunda Choowong ◽  
...  
Keyword(s):  
Fruiting Bodies ◽  
Ganoderma Australe

The isolation of lanosta-7,9(11),24-trien-3β,21-diol from the fungus ganoderma australe

1984 ◽  
Vol 23 (3) ◽  
pp. 686-687 ◽  
Author(s):  
Amolak C. Jain ◽  
Sushil K. Gupta
Keyword(s):  
Ganoderma Australe

scholarly journals BASIDIOMICETOS DA CIDADE DE CASCAVEL – OESTE DO PARANÁ – E SUAS APLICAÇÕES EM BIOTECNOLOGIA

2006 ◽  
Vol 28 (65) ◽  
Author(s):  
Ingrids Mathias Vieira ◽  
Marcelo Henrique da Rocha ◽  
Edison Barbosa da Cunha ◽  
Marina Kimiko Kadowaki ◽  
Clarice Aoki Osaku
Keyword(s):  
Schizophyllum Commune ◽  
Pycnoporus Sanguineus ◽  
Ganoderma Applanatum ◽  
Ganoderma Australe ◽  
Phellinus Gilvus

Foram examinadas e identificadas 18 amostras (8 gêneros e 3 famílias) de Basidiomycetes macroscópicos coletadas no período de novembro de 2005 a julho de 2006 na cidade de Cascavel/PR/BR. As espécies identificadas foram: Schizopora carneo-lutea, Poria lenis, Pycnoporus sanguineus, Trametes villosa, Schizophyllum commune, Ganoderma applanatum, Ganoderma resinaceum, Ganoderma australe, Coriolopsis polyzona, Phellinus gilvus. O gênero melhor representado foi Ganoderma, com três táxons distintos e as espécies mais freqüentes foram Trametes villosa e Coriolopsis polyzona. Foi elaborada uma chave de identificação para os táxons encontrados.

Selection of a pH- and temperature-stable laccase from Ganoderma australe and its application for bioremediation of textile dyes

2021 ◽  
Vol 299 ◽  
pp. 113619
Author(s):  
Jing Si ◽  
Yi Wu ◽  
Hong-Fei Ma ◽  
Yong-Jia Cao ◽  
Yi-Fei Sun ◽  
...  
Keyword(s):  
Textile Dyes ◽  
Ganoderma Australe ◽  
Selection Of

scholarly journals An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma australe

2019 ◽  
Vol 87 (3) ◽  
pp. 21 ◽  
Author(s):  
Krisyanti Budipramana ◽  
Junaidin Junaidin ◽  
Komar Ruslan Wirasutisna ◽  
Yanatra Budi Pramana ◽  
Sukrasno Sukrasno
Keyword(s):  
In Silico ◽  
Dipeptidyl Peptidase ◽  
Antidiabetic Activity ◽  
Resonance Spectroscopy ◽  
Dipeptidyl Peptidase 4 ◽  
13C Nuclear Magnetic Resonance ◽  
Study Results ◽  
In Silico Study ◽  
Ganoderma Australe ◽  
Isolated Compound

Background: Ganoderma fungus is rich in terpenoids. These compounds are known for their anti-hyperglycemic activities. However, the study of terpenoids as the secondary metabolite from Ganoderma as a dipeptidyl peptidase-4 (DPP-4) inhibitor remains unexplored. In addition, we examined the α-glucosidase inhibition activity. Objective: This study aimed to isolate the major terpenoid from non-laccate Ganoderma and examined its inhibitor activity on DPP-4 and α-glucosidase enzymes, and its interaction. Methods: The compound was isolated using column chromatography from Ganoderma australe. The structure of the isolated compound was confirmed by 1H and 13C nuclear magnetic resonance spectroscopy, while the inhibitory activity was evaluated using an enzymatic assay. The interaction of the isolated compound with DPP-4 and α-glucosidase enzymes was investigated using an in silico study. Results: The isolated compound was identified as stellasterol; IC50 values for DPP-4 and α-glucosidase inhibitor were 427.39 µM and 314.54 µM, respectively. This study revealed that the inhibitory effect of stellasterol on DPP-4 enzyme is through hydrophobic interaction, while the α-glucosidase enzyme is due to the interaction with six amino acids of the enzyme. Conclusion: Stellasterol is the major component of the steroid from G. australe. Enzyme inhibitory assay and in silico study suggest that stellasterol may contribute antidiabetic activity with a mechanism closer to acarbose rather than to sitagliptin.

scholarly journals Bioprospecting of the agaricomycete Ganoderma australe GPC191 as novel source for l-asparaginase production

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Meghna Chakraborty ◽  
Srividya Shivakumar
Keyword(s):  
Bromothymol Blue ◽  
Future Application ◽  
Phenol Red ◽  
Statistical Validation ◽  
Food Industries ◽  
Potential Source ◽  
High Zone ◽  
Ganoderma Australe ◽  
Index Value ◽  
First Time

Abstractl-Asparaginase is a therapeutically and industrially-competent enzyme, acting predominantly as an anti-neoplastic and anti-cancerous agent. The existing formulations of prokaryotic l-asparaginase are often toxic and contain l-glutaminase and urease residues, thereby increasing the purification steps. Production of l-glutaminase and urease free l-asparaginase is thus desired. In this research, bioprospecting of isolates from the less explored class Agaricomycetes was undertaken for l-asparaginase production. Plate assay (using phenol red and bromothymol blue dyes) was performed followed by estimation of l-asparaginase, l-glutaminase and urease activities by Nesslerization reaction for all the isolates. The isolate displaying the desired enzyme production was subjected to morphological, molecular identification, and phylogenetic analysis with statistical validation using Jukes-Cantor by Neighbour-joining tree of Maximum Likelihood statistical method. Among the isolates, Ganoderma australe GPC191 with significantly high zone index value (5.581 ± 0.045 at 120 h) and enzyme activity (1.57 ± 0.006 U/mL), devoid of l-glutaminase and urease activity was selected. The present study for the first-time reported G. australe as the potential source of l-glutaminase and urease-free l-asparaginase and also is one of the few studies contributing to the literature of G. australe in India. Hence, it can be postulated that it may find its future application in pharmaceutical and food industries.

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