Preparation of β-lactoglobulin/gum arabic complex nanoparticles for encapsulation and controlled release of EGCG in simulated gastrointestinal digestion model

2021 ◽  
Vol 354 ◽  
pp. 129516
Author(s):  
Jian Gao ◽  
Yuezhong Mao ◽  
Chuyue Xiang ◽  
Mengna Cao ◽  
Gerui Ren ◽  
...  
Keyword(s):  
Controlled Release ◽  
Gum Arabic ◽  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Β Lactoglobulin

Epitopes resistance to the simulated gastrointestinal digestion of β-lactoglobulin submitted to two-step enzymatic modification

2015 ◽  
Vol 72 ◽  
pp. 191-197 ◽  
Author(s):  
Mariana Battaglin Villas-Boas ◽  
Sara Benedé ◽  
Ricardo de Lima Zollner ◽  
Flavia Maria Netto ◽  
Elena Molina
Keyword(s):  
Enzymatic Modification ◽  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Β Lactoglobulin

The effect of gel structure on the kinetics of simulated gastrointestinal digestion of bovine β-lactoglobulin

2012 ◽  
Vol 134 (4) ◽  
pp. 2156-2163 ◽  
Author(s):  
Adam Macierzanka ◽  
Franziska Böttger ◽  
Laura Lansonneur ◽  
Rozenn Groizard ◽  
Anne-Sophie Jean ◽  
...  
Keyword(s):  
Gastrointestinal Digestion ◽  
Gel Structure ◽  
Simulated Gastrointestinal Digestion ◽  
Β Lactoglobulin ◽  
Kinetics Of

Effect of simulated gastrointestinal digestion on the antihypertensive properties of synthetic β-lactoglobulin peptide sequences

2007 ◽  
Vol 74 (3) ◽  
pp. 336-339 ◽  
Author(s):  
Blanca Hernández-Ledesma ◽  
Marta Miguel ◽  
Lourdes Amigo ◽  
Maria Amaya Aleixandre ◽  
Isidra Recio
Keyword(s):  
Inhibitory Activity ◽  
Ace Inhibition ◽  
Antihypertensive Activity ◽  
Gastrointestinal Digestion ◽  
Ace Inhibitory Activity ◽  
Simulated Gastrointestinal Digestion ◽  
The Impact ◽  
Β Lactoglobulin ◽  
Ace Inhibitory

In this study, the antihypertensive activity in spontaneously hypertensive rats of two peptides isolated from β-lactoglobulin hydrolysates with thermolysin was evaluated. These peptides, with sequences LLF [β-lg f(103–105)] and LQKW [β-lg f(58–61)], showed potent in vitro ACE-inhibitory activity. Two hours after administration, both sequences caused a clear and significant decrease in the blood pressure of these rats. The impact of a simulated gastrointestinal digestion on ACE-inhibitory and antihypertensive activities of these peptides was also studied. The results showed that both fragments were susceptible to proteolytic degradation after incubation with pepsin and Corolase PP®. In addition, their in vitro ACE-inhibitory activity decreased after the simulated digestion. It is likely that fragment LQK was the active end product of the gastrointestinal digestion of peptide LQKW. The fragment LL, observed after digestion of peptide LLF, probably exert its antihypertensive effect through a mechanism of action different than ACE-inhibition.

Bioaccessibility of Tudela artichoke (Cynara scolymus cv. Blanca de Tudela) (poly)phenols: the effects of heat treatment, simulated gastrointestinal digestion and human colonic microbiota

2021 ◽  
Author(s):  
Maite Domínguez-Fernández ◽  
Iziar A. Ludwig ◽  
María-Paz De Peña ◽  
Concepción Cid
Keyword(s):  
Heat Treatment ◽  
Gastrointestinal Digestion ◽  
Cynara Scolymus ◽  
Simulated Gastrointestinal Digestion ◽  
Catabolic Activity ◽  
Colonic Microbiota ◽  
Positive Effect

Heat treatment exerts a positive effect on the bioaccessibility of artichoke (poly)phenols after gastrointestinal digestion. In the first 2 h of fermentation, native (poly)phenols were readily degraded by an important microbial catabolic activity.

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