Chemical compounds and synergistic antifungal properties of Thymus kotschanus essential oil plus ketoconazole against Candida spp

Essential oils obtained from many plants showed various kinds of insecticidal properties; some of them have been considered as alternative insecticides for pest control. The present study was aimed at determining the chemical composition of the essential oil from the roots of Bupleurum bicaule Helm, as well as evaluating the contact and repellent activities of the oil and four identified compounds against Lasioderma serricorne and Liposcelis bostrychophila adults. The essential oil was extracted by hydrodistillation, and its components were analyzed by gas chromatography-mass spectrometry (GC-MS). 26 components were determined and the main compounds included trans-2-isopropylbicyclo[4.3.0]non-3-en-8-one (25.9%), 4,5-dimethyl-1,2,3,6,7,8,8a,8b-octahydrobiphenylene (23.5%), and 1,4-dimethoxy-2-tert-butylbenzene (4.3%). It was found that the essential oil exhibited contact toxicity against L. serricorne (LD50 = 11.91 μg/adult), but the contact toxicity against L. bostrychophila could not be observed. The essential oil also showed strong repellent activity against L. serricorne with percent repellency of 100% at 78.63 nl/cm2. Four chemical compounds, 1,4-dimethoxy-2-tert-butylbenzene, bornyl acetate, (2E,4E)-2,4-nonadienal, and β-bisabolene, exhibited various levels of bioactivities. The experimental results indicated that the essential oil of B. bicaule and its individual compounds could be used in insecticidal and repellent strategies for stored product insects.

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Antimicrobial activity of the essential oil of Cymbopogon citratus (DC) Stapf. on Staphylococcus spp., Streptococcus mutans and Candida spp.

Revista Brasileira de Plantas Medicinais ◽

10.1590/s1516-05722013000400002 ◽

2013 ◽

Vol 15 (4) ◽

pp. 474-482 ◽

Cited By ~ 5

Author(s):

RBA Almeida ◽

G Akisue ◽

LML Cardoso ◽

JC Junqueira ◽

AO C Jorge

Keyword(s):

Antimicrobial Activity ◽

Essential Oil ◽

Streptococcus Mutans ◽

Control Group ◽

Minimal Bactericidal Concentration ◽

Cymbopogon Citratus ◽

Candida Spp ◽

Biofilm Growth ◽

Micro Organisms ◽

Staphylococcus Spp

Medicinal plants with fungicide action, antibacterial and anti-inflammatory effects are under investigation. The main purpose of this work was to evaluate the antimicrobial activity of the essential oil from Cymbopogon citratus (DC) Stapf. on strains of Staphylococcus spp., Streptococcus mutans and Candida spp. with planktonic and biofilm growth. To study the micro-organisms in planktonic cells, the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined by using 9 clinical strains for each species and 1 ATCC (American Type Culture Collection) from C. albicans, C. tropicalis, C. glabrata, S. aureus, S. epidermidis and S. mutans. In order to evaluate the effects of the essential oils on biofilms, strains of S. aureus (ATCC 6538), S. mutans (ATCC 35688) and C. albicans (ATCC 18804) were used. The biofilm was formed on acrylic resin discs with isolated micro-organisms or in associations. The number of colony-forming-units (CFU) obtained in each biofilm (CFU/ml) was submitted to Student's t statistical test. The results demonstrated that the essential oil of Cymbopogon citratus showed microbiostatic and microbicidal activity against all tested strains. The average CFU/ml for the biofilm of S. aureus, S. mutans and C. albicans, whether isolated or in association, was lower in the group treated with essential oil than in the control group.

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Composition, biological properties and therapeutic effects of lavender (Lavandula angustifolia L). A review

Herba Polonica ◽

10.2478/hepo-2014-0010 ◽

2014 ◽

Vol 60 (2) ◽

pp. 56-66 ◽

Cited By ~ 33

Author(s):

Renata Prusinowska ◽

Krzysztof B. Śmigielski

Keyword(s):

Essential Oil ◽

Chemical Compounds ◽

Antimicrobial Activities ◽

Biological Properties ◽

Climatic Conditions ◽

Quantitative Composition ◽

Therapeutic Effects ◽

Lavandula Angustifolia ◽

The Family ◽

Positive Effect

Abstract Lavender (Lavandula angustifolia) is a shrub of the family Lamiaceae, native to the Mediterranean region. The material used for herbal purposes includes lavender flowers (Lavandula flores) containing essential oil (3%), anthocyanins, phytosterols, sugars, minerals, and tannins. The qualitative and quantitative composition of the essential oil of lavender is variable and depends on genotype, growing location, climatic conditions, propagation, and morphological features. The essential oil contains over 300 chemical compounds. The dominant components are linalool, linalyl acetate, terpinen-4-ol, acetate lavandulol, oci-mene, and cineole. Lavender essential oil has good antioxidant and antimicrobial activities and a significant positive effect on the digestive and nervous systems. Lavender extract prevents dementia and may inhibit the growth of cancer cells, while lavender hydrolate is recommended for the treatment of skin problems and burns.

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Thymus mastichina: Composition and Biological Properties with a Focus on Antimicrobial Activity

Pharmaceuticals ◽

10.3390/ph13120479 ◽

2020 ◽

Vol 13 (12) ◽

pp. 479

Author(s):

Márcio Rodrigues ◽

Ana Clara Lopes ◽

Filipa Vaz ◽

Melanie Filipe ◽

Gilberto Alves ◽

...

Keyword(s):

Escherichia Coli ◽

Antimicrobial Activity ◽

Antioxidant Activity ◽

Essential Oil ◽

Biological Activities ◽

Scientific Information ◽

Biological Properties ◽

Fusarium Spp ◽

Candida Spp ◽

Pharmaceutical Industries

Thymus mastichina has the appearance of a semishrub and can be found in jungles and rocky lands of the Iberian Peninsula. This work aimed to review and gather available scientific information on the composition and biological properties of T. mastichina. The main constituents of T. mastichina essential oil are 1,8-cineole (or eucalyptol) and linalool, while the extracts are characterized by the presence of flavonoids, phenolic acids, and terpenes. The essential oil and extracts of T. mastichina have demonstrated a wide diversity of biological activities. They showed antibacterial activity against several bacteria such as Escherichia coli, Proteus mirabilis, Salmonella subsp., methicillin-resistant and methicillin-sensitive Staphylococcus aureus, Listeria monocytogenes EGD, Bacillus cereus, and Pseudomonas, among others, and antifungal activity against Candida spp. and Fusarium spp. Additionally, it has antioxidant activity, which has been evaluated through different methods. Furthermore, other activities have also been studied, such as anticancer, antiviral, insecticidal, repellent, anti-Alzheimer, and anti-inflammatory activity. In conclusion, considering the biological activities reported for the essential oil and extracts of T. mastichina, its potential as a preservative agent could be explored to be used in the food, cosmetic, or pharmaceutical industries.

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