scholarly journals Short-term exposure to ambient ozone associated with cardiac arrhythmias in healthy adults

Author(s):  
Lingyan Liu ◽  
Yutong Zhu ◽  
Hongbing Xu ◽  
Yang Wang ◽  
Tong Wang ◽  
...  
Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2518
Author(s):  
Ariana Lammers ◽  
Anne H. Neerincx ◽  
Susanne J. H. Vijverberg ◽  
Cristina Longo ◽  
Nicole A. H. Janssen ◽  
...  

Environmental factors, such as air pollution, can affect the composition of exhaled breath, and should be well understood before biomarkers in exhaled breath can be used in clinical practice. Our objective was to investigate whether short-term exposures to air pollution can be detected in the exhaled breath profile of healthy adults. In this study, 20 healthy young adults were exposed 2–4 times to the ambient air near a major airport and two highways. Before and after each 5 h exposure, exhaled breath was analyzed using an electronic nose (eNose) consisting of seven different cross-reactive metal-oxide sensors. The discrimination between pre and post-exposure was investigated with multilevel partial least square discriminant analysis (PLSDA), followed by linear discriminant and receiver operating characteristic (ROC) analysis, for all data (71 visits), and for a training (51 visits) and validation set (20 visits). Using all eNose measurements and the training set, discrimination between pre and post-exposure resulted in an area under the ROC curve of 0.83 (95% CI = 0.76–0.89) and 0.84 (95% CI = 0.75–0.92), whereas it decreased to 0.66 (95% CI = 0.48–0.84) in the validation set. Short-term exposure to high levels of air pollution potentially influences the exhaled breath profiles of healthy adults, however, the effects may be minimal for regular daily exposures.


2015 ◽  
Vol 26 (2) ◽  
pp. 162-166 ◽  
Author(s):  
Jessica A Montresor-López ◽  
Jeff D Yanosky ◽  
Murray A Mittleman ◽  
Amir Sapkota ◽  
Xin He ◽  
...  

Author(s):  
Alan da Silveira da Silveira Fleck ◽  
Margaux L. Sadoine ◽  
Stéphane Buteau ◽  
Eva Suarthana ◽  
Maximilien Debia ◽  
...  

Background: No study has compared the respiratory effects of environmental and occupational particulate exposure in healthy adults. Methods: We estimated, by a systematic review and meta-analysis, the associations between short term exposures to fine particles (PM2.5 and PM4) and certain parameters of lung function (FEV1 and FVC) in healthy adults. Results: In total, 33 and 14 studies were included in the qualitative synthesis and meta-analyses, respectively. In environmental studies, a 10 µg/m3 increase in PM2.5 was associated with an FEV1 reduction of 7.63 mL (95% CI: −10.62 to −4.63 mL). In occupational studies, an increase of 10 µg/m3 in PM4 was associated with an FEV1 reduction of 0.87 mL (95% CI: −1.36 to −0.37 mL). Similar results were observed with FVC. Conclusions: Both occupational and environmental short-term exposures to fine particles are associated with reductions in FEV1 and FVC in healthy adults.


2014 ◽  
Vol 24 (9) ◽  
pp. 700
Author(s):  
Jessica Anne Montresor-Lopez ◽  
Jeff D. Yanosky ◽  
Murray Mittleman ◽  
Amir Sapkota ◽  
Xin He ◽  
...  

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
H. Shin ◽  
P. Gogna ◽  
A. Maquiling ◽  
L. Haque ◽  
B. Burr ◽  
...  

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