Homogeneous synthesis of Ag nanoparticles-doped water-soluble cellulose acetate for versatile applications

Chitosan/cellulose acetate multimicrospheres (CCAM) were prepared by the method of W/O/W emulsion with no toxic reagents and had the size interval of 200--280µm. It was investigated as an ideal alternative to enhancement the adsorption of water-soluble dyes from wastewater. The correlation coefficients of adsorption isotherm showed that the Freundlich model was comparable to the Langmuir model. The 1/n was lower than 1.0, indicating that malachite green was favorably adsorbed by CCAM. Furthermore, the amount of malachite green absorbed steeply increased with increasing time and reached plateau values within 2 h and increased with increasing of initial concentration of malachite green from 5 to 25 mg/g.

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Improved Bioavailability of Poorly Water-Soluble Drug Curcumin in Cellulose Acetate Solid Dispersion

AAPS PharmSciTech ◽

10.1208/s12249-011-9732-9 ◽

2011 ◽

Vol 13 (1) ◽

pp. 159-166 ◽

Cited By ~ 75

Author(s):

Shuxin Wan ◽

Yingqian Sun ◽

Xiuxiang Qi ◽

Fengping Tan

Keyword(s):

Cellulose Acetate ◽

Solid Dispersion ◽

Water Soluble ◽

Water Soluble Drug ◽

Poorly Water Soluble ◽

Poorly Water Soluble Drug

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Carboxymethyl Cellulose Acetate Butyrate: A Review of the Preparations, Properties, and Applications

Journal of Drug Delivery ◽

10.1155/2014/575969 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 11

Author(s):

Mohamed El-Sakhawy ◽

Samir Kamel ◽

Ahmed Salama ◽

Hebat-Allah Sarhan

Keyword(s):

Cellulose Acetate ◽

Carboxymethyl Cellulose ◽

Solid Dispersions ◽

Pharmaceutical Research ◽

Amorphous Solid ◽

Water Soluble ◽

Cellulose Acetate Butyrate ◽

Wide Range ◽

Poorly Soluble ◽

Acetate Butyrate

Carboxymethyl cellulose acetate butyrate (CMCAB) has gained increasing importance in several fields, particularly in coating technologies and pharmaceutical research. CMCAB is synthesized by esterification of CMC sodium salt with acetic and butyric anhydrides. CMCAB mixed esters are relatively high molecular weight (MW) thermoplastic polymers with high glass transition temperatures (Tg). CMCAB ester is dispersible in water and soluble in a wide range of organic solvents, allowing varied opportunity to the solvent choice. It makes application of coatings more consistent and defect-free. Its ability to slow down the release rate of highly water-soluble compounds and to increase the dissolution of poorly soluble compounds makes CMCAB a unique and potentially valuable tool in pharmaceutical and amorphous solid dispersions (ASD) formulations.

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Determination of Sequence Distribution of Substituted and Unsubstituted Glucopyranose Units in Water-Soluble Cellulose Acetate Chain as Revealed by Enzymatic Degradation

Polymer Journal ◽

10.1295/polymj.24.1077 ◽

1992 ◽

Vol 24 (10) ◽

pp. 1077-1097 ◽

Cited By ~ 10

Author(s):

Hideki Iijima ◽

Keisuke Kowsaka ◽

Kenji Kamide

Keyword(s):

Cellulose Acetate ◽

Enzymatic Degradation ◽

Water Soluble ◽

Sequence Distribution

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Influence of nanofiber alignment on the release of a water-soluble drug from cellulose acetate nanofibers

Saudi Pharmaceutical Journal ◽

10.1016/j.jsps.2020.08.011 ◽

2020 ◽

Vol 28 (10) ◽

pp. 1210-1216 ◽

Cited By ~ 1

Author(s):

Prasopchai Patrojanasophon ◽

Siripran Tidjarat ◽

Praneet Opanasopit ◽

Tanasait Ngawhirunpat ◽

Theerasak Rojanarata

Keyword(s):

Cellulose Acetate ◽

Water Soluble ◽

Water Soluble Drug ◽

Nanofiber Alignment

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Partially Acetylated Cellulose Dissolved in Aqueous Solution: Physical Properties and Enzymatic Hydrolysis

Polymers ◽

10.3390/polym11111734 ◽

2019 ◽

Vol 11 (11) ◽

pp. 1734 ◽

Cited By ~ 1

Author(s):

Alfassi ◽

Rein ◽

Shpigelman ◽

Cohen

Keyword(s):

Aqueous Solution ◽

Surface Tension ◽

Enzymatic Hydrolysis ◽

Cellulose Acetate ◽

Persistence Length ◽

Water Soluble ◽

High Rate ◽

Cellulose Derivatives ◽

Molecular Aggregation ◽

Cellulose Dissolution

Cellulose acetate is one of the most important cellulose derivatives. The use of ionic liquids in cellulose processing was recently found to act both as a solvent and also as a reagent. A recent study showed that cellulose dissolution in the ionic liquid 1-ethyl-3-methylimidazoliumacetate (EMIMAc) mixed with dichloromethane (DCM) resulted in controlled homogenous cellulose acetylation; yielding water-soluble cellulose acetate (WSCA). This research investigated the properties of cellulose acetate prepared in this manner, in an aqueous solution. The results revealed that WSCA fully dissolves in water, with no significant sign of molecular aggregation. Its conformation in aqueous solution exhibited a very large persistence length, estimated as over 10 nm. The WSCA exhibited surface activity, significantly reducing the surface tension of water. Because of the molecular dissolution of WSCA in water, augmented by its amphiphilicity, aqueous solutions of WSCA exhibited an overwhelmingly high rate of enzymatic hydrolysis.

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