Increased aortic blood pressure augmentation in patients with congenital heart defects — A cross-sectional study in 1125 patients and 322 controls

2015 ◽  
Vol 184 ◽  
pp. 225-229 ◽  
Author(s):  
Jan Müller ◽  
Peter Ewert ◽  
Alfred Hager
Keyword(s):  
Blood Pressure ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Aortic Blood ◽  
Aortic Blood Pressure

scholarly journals Awareness of prenatal genetic tests and attitude towards termination of pregnancy regarding fetal congenital heart defects among clinicians in China: a multi-center cross-sectional study

2020 ◽  
Author(s):  
jian wang ◽  
zhuoyan li ◽  
jianping yang ◽  
yanan lu ◽  
yurong wu ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Cross Sectional Study ◽  
Termination Of Pregnancy ◽  
Genetic Service ◽  
Genetic Tests ◽  
Cross Sectional ◽  
Group 2 ◽  
Group 1

Abstract Background: This study was aim to figure out the level of awareness about providing genetic tests and the attitude towards termination of pregnancy (TOP) regarding fetal congenital heart defects (CHD) among clinicians in China.Methods: A total of 501 clinicians were divided into 2 groups: clinicians whose working hospital were available of prenatal genetic service were assigned into group 1, whose working hospital were not available of prenatal genetic service were assigned to group 2. The level of awareness and the attitude were evaluated according to scores of a questionnaire. Results: Among the 501 total clinicians, only 27.94% received a high score and 53.09% received a medium score, indicating a low level of awareness about prenatal genetic tests among clinicians. 31.62% clinicians in group 1, but only 24.19% in group 2 showed good awareness of providing genetic tests (P=0.023). About 44.3% of clinicians in group 1, but only by 29.4% of those in group 2 held optimistic attitudes towards minor CHDs and were less favor of TOP in minor CHDs (P=0.023). Conclusion: Prenatal genetic tests and counseling in hospital are necessary and should be improved in the management of fetal CHD in China.

Congenital Heart Defects in Patients with Classic Bladder Exstrophy: A Hitherto Neglected Association?

2021 ◽  
Author(s):  
Martin Promm ◽  
Stephan Gerling ◽  
Carsten P. Schepp ◽  
Wolfgang H. Rösch
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Demographic Data ◽  
Bladder Exstrophy ◽  
Postoperative Outcome ◽  
Cross Sectional Study ◽  
Systematic Evaluation ◽  
Cross Sectional ◽  
Term Care

Abstract Introduction Classic bladder exstrophy (BE) is regarded as an isolated malformation without any further anomalies, but some studies have indicated a higher incidence of cardiac anomalies. This cross-sectional study is planned to evaluate the prevalence of congenital heart defects (CHDs) and the clinical relevance for patients with BE admitted for primary closure. Materials and Methods Patients were prospectively recruited between March 2012 and January 2019. Patients' profiles including demographic data, results of transthoracic echocardiography (TTE), as well as essential peri- and postoperative data were assessed. Results Thirty-nine (25 boys and 14 girls) patients with BE (median age 61 days) underwent delayed primary bladder closure. Thirty-seven (24 boys and 13 girls) patients had received TTE 1 day before surgery. CHD was detected in 7 (18.9%) out of the 39 patients, but no clinical differences between patients with and without CHD were observed peri- or postoperatively. Discussion and Conclusion This prospective systematic evaluation shows an even higher rate of CHD in patients with BE than assumed previously. Although peri- and postoperative outcome did not differ between patients with and without CHD, we consider TTE an important additional method for ensuring a safe peri- and postoperative courses and a short- and long-term care for patients with CHD.

Prevalence and Pattern of Congenital Anomalies in a Tertiary Hospital in Central Vietnam

2019 ◽  
Vol 66 (2) ◽  
pp. 187-193
Author(s):  
Hoang Thi Nam Giang ◽  
Susanne Bechtold-Dalla Pozza ◽  
Sarah Ulrich ◽  
Le Khac Linh ◽  
Hoang Thi Tran
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Anomalies ◽  
Congenital Heart ◽  
Heart Defects ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Common Type ◽  
Cross Sectional ◽  
Live Births ◽  
Central Vietnam

Abstract Background Burden and pattern of congenital anomalies are insufficiently reported in Vietnam. This study aims to determine the prevalence and pattern of congenital anomalies in neonates in a tertiary hospital in central Vietnam. Methods A prospective cross-sectional study recruited all newborns with congenital anomalies in Da Nang Hospital for Women and Children—where nearly 60% neonates in the city are delivered. Results Over a 1-year period, 551 out of 14 335 registered live births were found to have congenital anomalies, equivalent to an overall prevalence of 384.4 per 10 000 live births. Congenital heart defects were the most common type (52.3%) with the prevalence of 200.9 per 10 000 live births, followed by anomalies of musculoskeletal system, digestive system. Conclusions This study revealed a high prevalence of congenital anomalies with the most common type being congenital heart defects in central Vietnam compared to both higher income countries and resource-limited settings.

The prevalence of congenital heart defects in infants with cholestatic disorders of infancy: a single-centre study

2016 ◽  
Vol 101 (9) ◽  
pp. 803-807 ◽  
Author(s):  
Aya M Fattouh ◽  
Engy A Mogahed ◽  
Nehal Abdel Hamid ◽  
Rodina Sobhy ◽  
Noha Saber ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Pulmonary Stenosis ◽  
Alagille Syndrome ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Echocardiographic Examination ◽  
Single Centre Study ◽  
Combined Lesions

BackgroundThere is deficiency of data about congenital heart defects (CHDs) in cholestatic disorders of infancy other than Alagille syndrome (AGS). We aimed to define the prevalence and types of CHDs in infants with various causes of cholestatic disorders of infancy.MethodsThis cross-sectional study was conducted on 139 infants presenting with cholestasis whether surgical or non-surgical. The study was carried out at the Pediatric Hepatology Unit, Cairo University Children's Hospital, Egypt. Full examination and investigations were done in an attempt to reach an aetiologic diagnosis for cholestasis, in addition to a comprehensive echocardiographic study.ResultsThe age at the onset of cholestasis ranged from 1 day to 7 months. Males constituted 61.2%. Biliary atresia (BA) was diagnosed in 39 patients (28%), AGS in 16 patients (11.5%), 27 patients had miscellaneous diagnoses and 57 cases had indeterminate aetiology. CHDs were detected in 55 patients (39.5%). Shunt lesions were detected in 24 patients (43.6%), pulmonary stenosis in 18 patients (32.7%) and combined lesions in 9 patients (16.4%). Three patients (5.5%) had abnormal cardiac situs. Only seven patients had clinical presentation suggestive of CHD. CHDs were detected in 14 patients with BA (35.9%), 15 patients with AGS (93.7%) and 26 patients in the remaining group (30.9%).ConclusionCHDs are not uncommon among cholestatic infants and are mostly asymptomatic. Echocardiographic examination of cholestatic infants is recommended particularly for patients with BA before undergoing hepatic portoenterostomy as presence of CHD may impact the anaesthetic planning and affect the outcome of hepatobiliary surgery.

scholarly journals Blood Pressure and Tooth Loss: A Large Cross-Sectional Study with Age Mediation Analysis

2021 ◽  
Vol 18 (1) ◽  
pp. 285
Author(s):  
José João Mendes ◽  
João Viana ◽  
Filipe Cruz ◽  
Dinis Pereira ◽  
Sílvia Ferreira ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Tooth Loss ◽  
Cross Sectional Study ◽  
Mediation Effect ◽  
Sectional Study ◽  
Cross Sectional ◽  
Undiagnosed Hypertension ◽  
Dental Hospital ◽  
Continuous Measures ◽  
Effect Of Age

We aimed to investigate the association between blood pressure (BP) and tooth loss and the mediation effect of age. A cross-sectional study from a reference dental hospital was conducted from September 2017 to July 2020. Single measures of BP were taken via an automated sphygmomanometer device. Tooth loss was assessed through oral examination and confirmed radiographically. Severe tooth loss was defined as 10 or more teeth lost. Additional study covariates were collected via sociodemographic and medical questionnaires. A total of 10,576 patients were included. Hypertension was more prevalent in severe tooth loss patients than nonsevere tooth lost (56.1% vs. 39.3%, p < 0.001). The frequency of likely undiagnosed hypertension was 43.4%. The adjusted logistic model for sex, smoking habits and body mass index confirmed the association between continuous measures of high BP and continuous measures of tooth loss (odds ratio (OR) = 1.05, 95% CI: 1.03–1.06, p < 0.001). Age mediated 80.0% and 87.5% of the association between periodontitis with both systolic BP (p < 0.001) and diastolic BP (p < 0.001), respectively. Therefore, hypertension and tooth loss are associated, with a consistent mediation effect of age. Frequency of undiagnosed hypertension was elevated. Age, gender, active smoking, and BMI were independently associated with raised BP.

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