scholarly journals Cardiopulmonary fitness in children with congenital heart diseases versus healthy children: A multicenter cross-sectional study

2018 ◽  
Vol 10 (2) ◽  
pp. 257-258
Author(s):  
M. Rola ◽  
A. Gavotto ◽  
S. Guillaumont ◽  
M. Vincenti ◽  
C. Bredy ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Congenital Heart Diseases ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cardiopulmonary Fitness

scholarly journals Quality of life among children with congenital heart diseases: Comparative multi-center cross-sectional study

2013 ◽  
Vol 106 (8-9) ◽  
pp. 470
Author(s):  
P. Amedro ◽  
R. Dorka ◽  
S. Moniotte ◽  
S. Guillaumont ◽  
M.C. Picot ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Congenital Heart Diseases ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Cardiopulmonary fitness in children with congenital heart diseases versus healthy children

Heart ◽  
2017 ◽  
Vol 104 (12) ◽  
pp. 1026-1036 ◽  
Author(s):  
Pascal Amedro ◽  
Arthur Gavotto ◽  
Sophie Guillaumont ◽  
Helena Bertet ◽  
Marie Vincenti ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Female Gender ◽  
Cardiopulmonary Exercise Test ◽  
Congenital Heart Diseases ◽  
Healthy Children ◽  
Normal Children ◽  
Cross Sectional ◽  
Cardiopulmonary Fitness

ObjectiveWe aimed to compare the cardiopulmonary fitness of children with congenital heart diseases (CHD) with that of age-adjusted and gender-adjusted controls. We also intended to identify clinical characteristics associated with maximum oxygen uptake (VO2max) in this population.Methods and resultsWe included in a cross-sectional multicentre study a total of 798 children (496 CHD and 302 controls) who underwent a complete cardiopulmonary exercise test (CPET). The association of clinical characteristics with VO2max was studied using a multivariate analysis. Mean VO2max in the CHD group and control represented 93%±20% and 107%±17% of predicted values, respectively. VO2max was significantly lower in the CHD group, overall (37.8±0.3vs 42.6±0.4 mL/kg/min, P<0.0001) and for each group (P<0.05). The mean VO2max decline per year was significantly higher in CHD than in the controls overall (−0.84±0.10 vs −0.19±0.14 mL/kg/min/year, P<0.01), for boys (−0.72±0.14vs 0.11±0.19 mL/kg/min/year, P<0.01) and for girls (−1.00±0.13 vs −0.55±0.21 mL/kg/min/year, P=0.05). VO2max was associated with body mass index, ventilatory anaerobic threshold, female gender, restrictive ventilatory disorder, right ventricle systolic hypertension, tricuspid regurgitation, the number of cardiac catheter or surgery procedures, and the presence of a genetic anomaly.ConclusionsAlthough the magnitude of the difference was not large, VO2max among children with CHD was significantly lower than in normal children. We suggest performing CPET in routine follow-up of these patients.Trial registration numberClinicalTrials.gov NCT01202916; Post-results.

scholarly journals Quality of Life of Children with Congenital Heart Diseases: A Multicenter Controlled Cross-Sectional Study

2015 ◽  
Vol 36 (8) ◽  
pp. 1588-1601 ◽  
Author(s):  
P. Amedro ◽  
R. Dorka ◽  
S. Moniotte ◽  
S. Guillaumont ◽  
A. Fraisse ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Congenital Heart Diseases ◽  
Sectional Study ◽  
Cross Sectional

Thiamine levels in Indonesian children with congenital heart diseases undergoing surgery using cardiopulmonary bypass machine

2021 ◽  
pp. 021849232110241
Author(s):  
Eva M Marwali ◽  
Putri Caesa ◽  
Yoel Purnama ◽  
Muhammad Rayhan ◽  
Novik Budiwardhana ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
High Performance ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Congenital Heart Diseases ◽  
Chromatography Method ◽  
Cross Sectional ◽  
Before And After ◽  
Liquid Chromatography Method

Background This study evaluated thiamine levels in Indonesian children with congenital heart diseases before and after cardiopulmonary bypass and their relationship with clinical and surgical outcomes. Method A prospective, single center cross-sectional study was conducted to evaluate thiamine levels in 25 children undergoing congenital heart diseases surgery with cardiopulmonary bypass procedure. Thiamine levels were quantified using a high-performance liquid chromatography method. Result Preoperative thiamine deficiency was observed in one subject. Thiamine levels did not differ statistically between nutritional status and clinical outcomes categories. There were no significant changes in thiamine levels before and after cardiopulmonary bypass (median pre versus post (P25–75): 50 ng/mL (59.00–116.00) and 83.00 ng/mL (70.00–101.00), p = 0.84), although a significant reduction in thiamine levels were observed with longer cardiopulmonary bypass duration ( p = 0.017, R = −0.472). Conclusion Thiamine levels were not significantly impacted by cardiac surgery except in patients undergoing extremely long cardiopulmonary bypass duration. However, clinical outcome was not affected by thiamine levels.

scholarly journals Association of congenital heart diseases with extracardiac anomalies

2017 ◽  
Vol 4 (5) ◽  
pp. 1807 ◽  
Author(s):  
Mithlesh Dewangan
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Prospective Observational Study ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Congenital Heart Diseases ◽  
Cross Sectional ◽  
Medical College ◽  
Jawaharlal Nehru

Background: Congenital heart diseases are one of the main causes of death among the congenital malformations. An extracardiac malformation further increases the risk of morbidity and mortality to these patients, in addition to risks of surgical correction. So here comes the importance of extracardiac malformation.Methods:This prospective observational study was conducted at Neonatology Section, Department of Pediatrics, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh. The study was conducted over a period of 2 years (from January 2015 to December 2016). Newborns with congenital heart disease were examined for extracardiac defects.Results: This hospital based cross-sectional study found that there were 121 cases of congenital heart diseases among 11030 live births making an incidence of 1.09% Out of these 73.5% were acyanotic heart diseases and 26.5% were cyanotic heart disease. Extracardiac anomalies were found in 38 (31.5%) cases.Conclusions:Association of Congenital heart disease with extracardiac anomalies is well known. Syndromes are most commonly associated. 

scholarly journals Mandibular range of motion in children with juvenile idiopathic arthritis with and without clinically established temporomandibular joint involvement and in healthy children; a cross-sectional study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Willemijn F. C. de Sonnaville ◽  
Caroline M. Speksnijder ◽  
Nicolaas P. A. Zuithoff ◽  
Daan R. C. Verkouteren ◽  
Nico W. Wulffraat ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Range Of Motion ◽  
Temporomandibular Joint ◽  
Cross Sectional Study ◽  
Joint Involvement ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Explanatory Factors ◽  
Left And Right

Abstract Background Recognition of temporomandibular joint (TMJ) involvement in children with juvenile idiopathic arthritis (JIA) has gained increasing attention in the past decade. The clinical assessment of mandibular range of motion characteristics is part of the recommended variables to detect TMJ involvement in children with JIA. The aim of this study was to explore explanatory variables for mandibular range of motion outcomes in children with JIA, with and without clinically established TMJ involvement, and in healthy children. Methods This cross-sectional study included children with JIA and healthy children of age 6–18 years. Mandibular range of motion variables included active and passive maximum interincisal opening (AMIO and PMIO), protrusion, laterotrusion, dental midline shift in AMIO and in protrusion. Additionally, the TMJ screening protocol and palpation pain were assessed. Adjusted linear regression analyses of AMIO, PMIO, protrusion, and laterotrusion were performed to evaluate the explanatory factors. Two adjusted models were constructed: model 1 to compare children with JIA and healthy children, and model 2 to compare children with JIA with and without TMJ involvement. Results A total of 298 children with JIA and 169 healthy children were included. Length was an explanatory variable for the mandibular range of motion excursions. Each centimeter increase in length increased AMIO (0.14 mm), PMIO (0.14 mm), and protrusion (0.02 mm). Male gender increased AMIO by 1.35 mm. Having JIA negatively influenced AMIO (3.57 mm), PMIO (3.71 mm), and protrusion (1.03 mm) compared with healthy children, while the discrepancy between left and right laterotrusion raised 0.68 mm. Children with JIA and TMJ involvement had a 8.27 mm lower AMIO, 7.68 mm lower PMIO and 0.96 mm higher discrepancy in left and right laterotrusion compared to healthy children. Conclusion All mandibular range of motion items were restricted in children with JIA compared with healthy children. In children with JIA and TMJ involvement, AMIO, PMIO and the discrepancy between left and right laterotrusion were impaired more severely. The limitation in protrusion and laterotrusion was hardly clinically relevant. Overall, AMIO is the mandibular range of motion variable with the highest restriction (in millimeters) in children with JIA and clinically established TMJ involvement compared to healthy children.

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