In this paper, the author studied the effects of different stress ratios(R) and stress concentration factors(Kt) on the fatigue properties of WSTi6211 titanium alloy.Through S-N curve, the author obtained the fatigue ultimate strength of the material under different conditions and analyzed characteristics of fatigue fractures, including the crack source sourse, the crack growth region and the final rupture region. The results show that when Kt=1, R=0.5, the fatigue ultimate strength σD is 626MPa; when Kt = 1, R=0.06, the fatigue ultimate strength σD is 527.5MPa; when Kt=3, R=0.06, the ultimate fatigue strength σD is 267MPa. Fatigue performance is very sensitive to R and Kt. The larger R is, the larger the fatigue ultimate strength is. The larger Kt is, the smaller the fatigue limit strength is. The fracture morphology shows typical fatigue fracture morphology. Most of the cracks originate on the surface of specimens and have typical fatigue bands. With the decrease of stress, the area of crack growth zone increases.