The influence of lipid composition and surface charge on biodistribution of intact liposomes releasing from hydrogel-embedded vesicles

2014 ◽  
Vol 459 (1-2) ◽  
pp. 30-39 ◽  
Author(s):  
A. Alinaghi ◽  
M.R. Rouini ◽  
F. Johari Daha ◽  
H.R. Moghimi
Keyword(s):  
Surface Charge ◽  
Lipid Composition

scholarly journals Mycobacterium vaccae Adaptation to Disinfectants and Hand Sanitisers, and Evaluation of Cross-Tolerance with Antimicrobials

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 544
Author(s):  
Carla C. C. R. de Carvalho ◽  
Raquel Teixeira ◽  
Pedro Fernandes
Keyword(s):  
Autoimmune Diseases ◽  
Surface Charge ◽  
Membrane Permeability ◽  
Lipid Composition ◽  
Cross Tolerance ◽  
Mycobacterium Vaccae ◽  
Antituberculosis Therapy

Mycobacterium vaccae is being considered as an adjuvant to antituberculosis therapy, tested for the treatment of autoimmune diseases, and as an anti-depressive agent. This bacterium is ubiquitous in the environment and the widespread use of disinfectants and sanitisers may lead to its adaptation to these compounds. In the present study, M. vaccae cells adapted to these compounds mainly by making adjustments in their lipid composition and net surface charge. The modifications in the lipid composition led to changes in membrane permeability which resulted in increased tolerance towards levofloxacin, thioridazine, and omeprazole.

Liposome interaction with macrophages and foam cells for atherosclerosis treatment: effects of size, surface charge and lipid composition.

2021 ◽  
Author(s):  
Jinkai Tang ◽  
Moumita Rakshit ◽  
Huei Min Chua ◽  
Anastasia Darwitan ◽  
Luong T.H. Nguyen ◽  
...  
Keyword(s):  
Surface Charge ◽  
Lipid Composition ◽  
Treatment Effects ◽  
Foam Cells ◽  
Atherosclerosis Treatment

Imaging molecules adsorbed onto electrodes under potential control by scanning probe microscopy

1991 ◽  
Vol 49 ◽  
pp. 376-377 ◽  
Author(s):  
N.J. Tao ◽  
J.A. DeRose ◽  
P.I. Oden ◽  
S.M. Lindsay
Keyword(s):  
Surface Charge ◽  
Environmental Effects ◽  
Scanning Probe Microscopy ◽  
Statistical Significance ◽  
Electrochemical Methods ◽  
Surface Structures ◽  
Scanning Probe ◽  
Potential Control ◽  
Afm Imaging ◽  
Special Circumstances

Clemmer and Beebe have pointed out that surface structures on graphite substrates can be misinterpreted as biopolymer images in STM experiments. We have been using electrochemical methods to react DNA fragments onto gold electrodes for STM and AFM imaging. The adsorbates produced in this way are only homogeneous in special circumstances. Searching an inhomogeneous substrate for ‘desired’ images limits the value of the data. Here, we report on a reversible method for imaging adsorbates. The molecules can be lifted onto and off the substrate during imaging. This leaves no doubt about the validity or statistical significance of the images. Furthermore, environmental effects (such as changes in electrolyte or surface charge) can be investigated easily.

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