scholarly journals Evidence of the American Myxobolus dechtiari was introduced along with its host Lepomis gibbosus in Europe: Molecular and histological data

2021 ◽  
Vol 15 ◽  
pp. 51-57
Author(s):  
U. Goswami ◽  
K. Molnár ◽  
G. Cech ◽  
J.C. Eiras ◽  
P.K. Bandyopadhyay ◽  
...  
Keyword(s):  
Lepomis Gibbosus ◽  
Histological Data

Purification of Acetylcholinerase from Lepomis gibbosus Brain*

2011 ◽  
Vol 17 (1) ◽  
pp. 135-137
Author(s):  
Xia WANG ◽  
Mingjun LIU ◽  
Jun’e GAO ◽  
Dun LI
Keyword(s):  
Lepomis Gibbosus

EFFECTIVENESS OF PUNCTURE BIOPSIES OF THE PANCREAS UNDER ULTRASOUND GUIDANCE

2017 ◽  
Vol 63 (3) ◽  
pp. 475-478
Author(s):  
Alla Mikhetko ◽  
Dmitriy Zakharov ◽  
V. Perov ◽  
I. Belova
Keyword(s):  
Ultrasound Guidance ◽  
Morphological Investigation ◽  
Cytological Examination ◽  
Comparison Of Results ◽  
Histological Data ◽  
The Republic ◽  
Cytological Method ◽  
Cystic Pancreatic Lesions ◽  
Histological Form

The results of 205 puncture biopsies of solid and cystic pancreatic lesions performed in 202 patients at the Republican Oncological Dispensary of the Republic of Karelia for a 7-year period (2009-2015) are presented. Informative material for morphological investigation was obtained in 95.5% of cases. A comparison of results of cytological examination of the material from 56 patients with pancreatic lesions with histological data was carried out. The efficiency of the cytological method was 90.6%, sensitivity - 87.8%, specificity - 100%. To determine histological form of tumor in cytological examination of the material of the pancreas was successful in 82.1% of cases.

scholarly journals A Clinical and Histological Study about the Socket Preservation in a Patient under Oral Bisphosphonates Treatment: A Case Report

Biology ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 262
Author(s):  
Antonello Falco ◽  
Francesco Bataccia ◽  
Lorenzo Vittorini Orgeas ◽  
Federico Perfetti ◽  
Mariangela Basile ◽  
...  
Keyword(s):  
Case Report ◽  
Histological Study ◽  
Healing Process ◽  
Signs And Symptoms ◽  
Bisphosphonate Therapy ◽  
Graft Material ◽  
Oral Bisphosphonates ◽  
Socket Preservation ◽  
Oral Bisphosphonate ◽  
Histological Data

The aim of the present study is to assess the clinical and histological healing of a post-extractive alveolus following the procedure for socket preservation, in a patient receiving oral bisphosphonates for more than 6 years. After the extraction, enzymatically-deantigenated horse bone granules and an equine pericardium membrane were used to preserve the tooth socket. The patient was placed on a monthly follow-up in order to monitor the healing process. A 3 mm trephine bur was used to drill the bone for implant site preparation and to collect the bone sample. No signs and symptoms related to osteonecrosis of the jaws were reported. Histological data showed that, after 5 months, the mean percentages of trabecular bone, bone marrow and residual bone graft were respectively 45.74 ± 0.09%, 48.09 ± 0.08%, and 6.16 ± 0.01%. The residual graft material appeared to be osteointegrated and none of the particles appeared to be encapsulated. The present case report supports the guidelines that assume that patients undergoing oral bisphosphonate therapy can be eligible for surgical therapy. More clinical studies with larger sample sizes are needed to support this clinical evidence.

scholarly journals Urinary Cytokines Reflect Renal Inflammation in Acute Tubulointerstitial Nephritis: A Multiplex Bead-Based Assay Assessment

2021 ◽  
Vol 10 (13) ◽  
pp. 2986
Author(s):  
Laura Martinez Valenzuela ◽  
Juliana Draibe ◽  
Oriol Bestard ◽  
Xavier Fulladosa ◽  
Francisco Gómez-Preciado ◽  
...  
Keyword(s):  
Tubulointerstitial Nephritis ◽  
Urinary Concentration ◽  
Blood Eosinophil ◽  
Acute Tubulointerstitial Nephritis ◽  
Luminex Assay ◽  
Non Invasive ◽  
Urinary Levels ◽  
Histological Data ◽  
The Individual ◽  
Multiplex Bead

Background: Acute tubulointerstitial nephritis (ATIN) diagnosis lays on histological assessment through a kidney biopsy, given the absence of accurate non-invasive biomarkers. The aim of this study was to evaluate the accuracy of different urinary inflammation-related cytokines for the diagnostic of ATIN and its distinction from acute tubular necrosis (ATN). Methods: We included 33 patients (ATIN (n = 21), ATN (n = 12)), and 6 healthy controls (HC). We determined the urinary levels of 10 inflammation-related cytokines using a multiplex bead-based Luminex assay at the time of biopsy and after therapy, and registered main clinical, analytical and histological data. Results: At the time of biopsy, urinary levels of I-TAC/CXCL11, CXCL10, IL-6, TNFα and MCP-1 were significantly higher in ATIN compared to HC. A positive correlation between the extent of the tubulointerstitial cellular infiltrates in kidney biopsies and the urinary concentration of I-TAC/CXCL11, MIG/CXCL9, CXCL10, IL17, IFNα, MCP1 and EGF was observed. Notably, I-TAC/CXCL11, IL-6 and MCP-1 were significantly higher in ATIN than in ATN, with I-TAC/CXCL11 as the best discriminative classifier AUC (0.77, 95% CI 0.57–0.95, p = 0.02). A combinatory model of these three urinary cytokines increased the accuracy in the distinction of ATIN/ATN compared to the individual biomarkers. The best model resulted when combining the three cytokines with blood eosinophil and urinary leukocyte counts (LR = 9.76). Follow-up samples from 11ATIN patients showed a significant decrease in I-TAC/CXCL11, MIG/CXCL9 and CXCL10 levels. Conclusions: Urinary I-TAC/CXCL11, CXCL10, IL6 and MCP-1 levels accurately distinguish patients developing ATIN from ATN and healthy individuals and may serve as novel non-invasive biomarkers in this disease.

scholarly journals COVID-19 and myocarditis: a systematic review and overview of current challenges

2021 ◽  
Author(s):  
Teresa Castiello ◽  
Georgios Georgiopoulos ◽  
Gherardo Finocchiaro ◽  
Monaco Claudia ◽  
Andrea Gianatti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systolic Function ◽  
Imaging Modality ◽  
Current Evidence ◽  
Cochrane Library ◽  
Myocardial Inflammation ◽  
Prognostic Impact ◽  
Direct Role ◽  
Potential Implication ◽  
Histological Data

AbstractMyocardial inflammation in COVID-19 has been documented. Its pathogenesis is not fully elucidated, but the two main theories foresee a direct role of ACE2 receptor and a hyperimmune response, which may also lead to isolated presentation of COVID-19-mediated myocarditis. The frequency and prognostic impact of COVID-19-mediated myocarditis is unknown. This review aims to summarise current evidence on this topic. We performed a systematic review of MEDLINE and Cochrane Library (1/12/19–30/09/20). We also searched clinicaltrials.gov for unpublished studies testing therapies with potential implication for COVID-19-mediated cardiovascular complication. Eligible studies had laboratory confirmed COVID-19 and a clinical and/or histological diagnosis of myocarditis by ESC or WHO/ISFC criteria. Reports of 38 cases were included (26 male patients, 24 aged < 50 years). The first histologically proven case was a virus-negative lymphocytic myocarditis; however, biopsy evidence of myocarditis secondary to SARS-CoV-2 cardiotropism has been recently demonstrated. Histological data was found in 12 cases (8 EMB and 4 autopsies) and CMR was the main imaging modality to confirm a diagnosis of myocarditis (25 patients). There was a substantial variability in biventricular systolic function during the acute episode and in therapeutic regimen used. Five patients died in hospital. Cause-effect relationship between SARS-CoV-2 infection and myocarditis is difficult to demonstrate. However, current evidence demonstrates myocardial inflammation with or without direct cardiomyocyte damage, suggesting different pathophysiology mechanisms responsible of COVID-mediated myocarditis. Established clinical approaches should be pursued until future evidence support different actions. Large multicentre registries are advisable to elucidate further.

The functional allometry of semicircular canals, fins, and body dimensions in the juvenile centrarchid fish, Lepomis gibbosus (L.)

Development ◽  
1973 ◽  
Vol 29 (3) ◽  
pp. 721-743
Author(s):  
Howard C. Howland ◽  
Joseph Masci
Keyword(s):  
Body Mass ◽  
Semicircular Canal ◽  
Semicircular Canals ◽  
Lepomis Gibbosus ◽  
Swimming Velocity ◽  
Body Dimensions ◽  
Moments Of Inertia ◽  
Significant Difference ◽  
Vertical Semicircular Canal ◽  
Vertical Semicircular Canals

1. The ontogenetic allometry of radii of curvature and the tube radii of the semicircular canals of approximately 85 juvenile (2–20 g) centrarchids of the species Lepomis gibbosus (L.) was investigated. The radii of curvature of the semicircular canals have different allometries; these arefor the anterior vertical, posterior vertical and horizontal canals respectively. The differences in growth exponents between the anterior and posterior vertical semicircular canals and between the anterior vertical and horizontal semicircular canals were statistically significant (P &lt; 0·02 and P &lt; 0·05 respectively). 2. Body mass and standard length were almost equally good predictors of the radii of curvature of the anterior vertical semicircular canals, but body mass was the better predictor of the radii of curvature of the posterior vertical and horizontal semicircular canals, as judged by the magnitude of the mean squares about the logarithmic regressions of radii on length and mass. 3. By measuring and estimating the area moments of the fins of the fish, the moments of inertia about various axes and the allometry of the characteristic swimming velocity of the fish, we attempted to account for the magnitude and direction of the differences in allometric growth exponents of the radii of curvature of the semicircular canals. Unexplained by our best estimate of growth exponents was the very high value observed for the posterior vertical semicircular canals. 4. No significant correlation could be found between the residuals of the major dimensions of the posterior vertical semicircular canals and those of body width or depth once the influence of body mass was removed. This finding suggests the rejection of the hypothesis that the allometry of this semicircular canal is simply correlated with overall body expansion in its plane. 5. The discrepancies between our predictions and observations of growth exponents could be explained by a gradual increase of the spring constant of the semicircular canals on the order ofthough they may also be due to other factors neglected in our model, e.g. the allometry of the added mass of the fish. 6. No evidence suggested that the shape of the semicircular canals was altered over the size range of the fish we studied. However, among the fins of the fish and the major body dimensions, only the width and the depth of the fish exhibited growth constants that did not differ significantly from each other. 7. We computed the effective toroidal radii of the non-toroidal-shaped vertical semicircular canals and found that the equivalent toroidal radius of the anterior vertical semicircular canal was consistently greater than that of the posterior vertical semicircular canal. This difference is explicable on the basis of the different moments of inertia of the animal about axes through the center of gravity and parallel to the axes of the semicircular canals. 8. We computed the allometry of the ratios R̄/r2 for all three semicircular canals and found in accordance with the prediction of Jones & Spells that they did not differ significantly from zero. 9. The allometry of the outer tube radii of the several semicircular canals was determined, and, while there was no significant difference in the growth exponents of the tube radii, it was noted that the tube radius of the horizontal semicircular canal was consistently and significantly smaller than that of the vertical semicircular canal. We suggested that this difference might be due to the broader range of frequencies that the fish experienced about its yaw axis. 10. Taken as a whole the data and calculations of this paper generally support the theory that the dimensions of the semicircular canals and the ontogenetic changes in them attune the semicircular canals to the angular frequency spectra that the fish experience about their axes.

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