scholarly journals Interstitial Brachytherapy for Early-Stage Tongue Cancer: Analysis of the Long-term Treatment Results for Survival and Complications

2015 ◽  
Vol 93 (3) ◽  
pp. E300
Author(s):  
Y. Takeuchi ◽  
Y. Murakami ◽  
K. Kubo ◽  
H. Sakaguchi ◽  
N. Imano ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Early Stage ◽  
Term Treatment ◽  
Interstitial Brachytherapy ◽  
Treatment Results ◽  
Long Term Treatment

Analysis of long-term treatment outcomes and toxicty of HL

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e19536-e19536
Author(s):  
J. Y. Ngeow ◽  
R. Quek ◽  
M. Tao ◽  
H. C. Tan ◽  
L. Lim ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Early Stage ◽  
Local Population ◽  
Developed Countries ◽  
Term Treatment ◽  
Bulky Disease ◽  
Nodular Sclerosis ◽  
Long Term Treatment ◽  
Treatment Data

e19536 Background: Prognosis of patients with Hodgkin lymphoma (HL) has substantially improved but therapy of HL can however contribute to delayed toxicity. Long term treatment outcomes of HL in our local population were evaluated. Methods: Clinical and treatment data was prospectively collected from all patients with a histological diagnosis of HL. Patients were all fully staged with CT scan and bone marrow biopsy. Results: On the basis of 217 patients seen at the National Cancer Centre Singapore between 1990–2008, we found that there was a peak in young adulthood with 103 patients who were diagnosed before the age of 30 (48%), median age of presentation 32 (range 17–84). Patients who were young (< 30 years) were more likely to present with nodular sclerosis HL (p=0.0001). Treatment outcomes were comparable to other published series, 85% of cases received ABVD based treatment. 5 year OS for early stage HL was 92% and 88% for advanced stage HL. Overall FFTF was 93% at 5 years. Of note, comparing patients with early stage (Stage I/ II) HL (n=114) who had ABVD 4 cycles followed by involved field radiotherapy (IFRT) with those who received 6–8 cycles of ABVD, there was no difference in OS, FFTF (p= 0.99, 0.48 respectively). Bulky early stage HL who received 6 cycles of ABVD and IFRT had better FFTF rates than those who had just 4 cycles of ABVD followed by IFRT (p=0.06). In contrast, patients patients with advanced HL (Stage III/ IV) (n=70) who completed 6–8 cycles of ABVD did not benefit from additional IFRT even in the presence of bulky disease (n=15). Acute toxicities included that of bleomycin induced pneumonitis (BIP) seen in 15% of cases. Neither the omission of bleomycin nor the presence BIP adversely affected treatment outcomes. Hematological malignancies were seen in 1% of survivors appearing after a median of 7.3 years. Hypothyroidism was noted in 3% of cases. Conclusions: 1) Epidemiology of HL in Singapore is increasingly similar to that of developed countries with a peak in young adults. 2)Young age was predictive of a nodular sclerosis subtype 3) Abbreviated chemotherapy using 4 cycles of ABVD followed by IFRT performed similarly to 6 cycles of ABVD in early stage HL, but in patients with bulky disease this may not be sufficient. 4) BIP occurred in 15% of cases. BIP and the omission of bleomycin did not adversely affect treatment outcomes. No significant financial relationships to disclose.

Long-term treatment results for nasopharyngeal carcinoma: The Sahlgrenska University Hospital experience

2007 ◽  
Vol 46 (6) ◽  
pp. 817-827 ◽  
Author(s):  
Zahra Taheri-Kadkhoda ◽  
Thomas Björk-Eriksson ◽  
Karl-Axel Johansson ◽  
Claes Mercke
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Term Treatment ◽  
University Hospital ◽  
Treatment Results ◽  
Hospital Experience ◽  
Long Term Treatment

scholarly journals Method for Quantitative Evaluation of Spiral Tibial Fractures

2014 ◽  
Vol 21 (3) ◽  
pp. 27-33
Author(s):  
F. A Matsukatov ◽  
I. I Martel’
Keyword(s):  
Quantitative Evaluation ◽  
Preventive Measures ◽  
Term Treatment ◽  
Tibial Fractures ◽  
X Rays ◽  
Treatment Results ◽  
Long Term Treatment ◽  
Secondary Displacement ◽  
Series Of Experiments

To elaborate a method of quantitative evaluation of instable spiral tibial bones fractures as the basis for differential approach to secondary displacement prevention, x-rays of 312 patients were analyzed and a series of experiments to study spiral fractures peculiarities was performed. The factors responsible for the instable pattern of spiral tibial fractures were detected. Quantitative index of the risk of secondary displacement was calculated and preventive measures were elaborated on their basis. Proposed recommendations on secondary displacement prevention were used as a basis for the treatment of 83 patients using Matsukidis - Shevtsov apparatus. Long-term treatment results were studied in 59 (71%) patients. Excellent and good results were achieved in 51 (86.5%) and 8 (13.5%) patients, respectively. Neither satisfactory nor poor results were observed.

scholarly journals Long-term treatment results of Hodgkin's disease at two Japanese hospitals.

1995 ◽  
Vol 21 (1) ◽  
pp. 125-131
Author(s):  
Naofumi HAYABUCHI ◽  
Yoshihiko ONIZUKA ◽  
Seiya JO ◽  
Emi TABUCHI ◽  
Jun-ichi OMAGARI
Keyword(s):  
Hodgkin's Disease ◽  
Hodgkin’S Disease ◽  
Term Treatment ◽  
Treatment Results ◽  
Long Term Treatment
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