scholarly journals Influence of the Pain Duration on Pain Outcomes Following Palliative Radiotherapy for Painful Tumors: The Sooner the Irradiation, the Better?

2020 ◽  
Vol 108 (3) ◽  
pp. S34-S35
Author(s):  
T. Saito ◽  
K. Murotani ◽  
R. Toya ◽  
E. Tomitaka ◽  
T. Matsuyama ◽  
...  
Keyword(s):  
Palliative Radiotherapy ◽  
Pain Outcomes ◽  
Pain Duration

Outcomes After Percutaneous Surgery for Patients With Multiple Sclerosis-Related Trigeminal Neuralgia

Neurosurgery ◽  
2012 ◽  
Vol 71 (3) ◽  
pp. 581-586 ◽  
Author(s):  
Grant W. Mallory ◽  
John L. Atkinson ◽  
Kathy J. Stien ◽  
B. Mark Keegan ◽  
Bruce E. Pollock
Keyword(s):  
Multiple Sclerosis ◽  
Pain Relief ◽  
Trigeminal Neuralgia ◽  
Hazard Ratio ◽  
Percutaneous Surgery ◽  
Pain Location ◽  
Additional Surgery ◽  
Pain Outcomes ◽  
Pain Duration ◽  
Provide Pain Relief

Abstract BACKGROUND: Approximately 1% to 2% of patients with multiple sclerosis (MS) develop trigeminal neuralgia (TN). Percutaneous surgery is commonly performed in medically refractory cases. OBJECTIVE: To analyze the pain outcomes and complications of patients with MS-related trigeminal neuralgia (MS-TN) having percutaneous surgery. METHODS: Patients having balloon microcompression (BMC; n = 69) or glycerol rhizotomy (PRGR; n = 67) from 1997 to 2010 were reviewed retrospectively. Patients in the 2 groups were similar with regard to age, sex, pain location, and pain quality. Mean pain duration was longer in the PRGR group (54.6 vs 16 months; P < .001); more patients having BMC had prior surgery (87% vs 48%; P < .001). Outcomes were defined as excellent (no pain, no medications), good (no pain with medications), and poor. Median follow-up was 13 months (range, 0.25-132 months). RESULTS: Ninety-five patients initially had excellent (n = 45, 33%) or good (n = 50, 37%) outcomes. Pain relief was maintained in 58% of patients at 3 months and 28% at 2 years. There was no difference in excellent/good outcomes between the surgical groups (hazard ratio = 0.73; P = .14). No correlation was noted between pain relief and new or increased facial numbness (hazard ratio = 0.78; P = .19). Forty-four BMC patients (64%) had additional surgery compared with 36 PRGR patients (54%; P = .19). Complications were more frequent after BMC (17.4% vs 3.0%; P < .01). CONCLUSION: Percutaneous surgery for patients with MS-TN is less likely to provide pain relief than similar operations performed for patients with idiopathic TN. New trigeminal deficits did not correlate with better facial pain outcomes, supporting the concept that many patients with MS-TN have centrally mediated pain.

Predicting suicidal ideation in adolescents with chronic amplified pain: The roles of depression and pain duration.

2018 ◽  
Vol 15 (3) ◽  
pp. 309-315 ◽  
Author(s):  
Bernadette Lewcun ◽  
Traci M. Kennedy ◽  
Jenna Tress ◽  
Kimberly S. Miller ◽  
Jennifer Sherker ◽  
...  
Keyword(s):  
Suicidal Ideation ◽  
Pain Duration

Para-spermatic cord proximal-type epithelioid sarcoma

2021 ◽  
Vol 14 (1) ◽  
pp. e232385
Author(s):  
Jessica Farnan ◽  
Ellen Morrison ◽  
Derek Barrry Hennessey
Keyword(s):  
Spermatic Cord ◽  
Median Overall Survival ◽  
Palliative Chemotherapy ◽  
Epithelioid Sarcoma ◽  
Palliative Radiotherapy ◽  
Surgical Excision ◽  
Radical Excision ◽  
First Line ◽  
Left Groin ◽  
Painless Mass

Proximal-type epithelioid sarcoma is an ultra-rare, high-grade soft tissue malignancy usually presenting as a deep-seated painless mass in the proximal extremities. Most patients are diagnosed as young adults, between 20 and 40 years of age. Perineal and genital masses do occur but are extremely rare and represent a challenging tumour to diagnose and treat. Early radical excision is recommended due to its aggressive behaviour and poor prognosis. Median overall survival from initial diagnosis is 30 months. We present the case of a 22-year-old man with a left groin proximal-type epithelioid sarcoma who is sadly deceased 12 months after initial presentation despite early surgical excision, completion of both first-line and palliative chemotherapy, and palliative radiotherapy.

scholarly journals Prolonged SARS-CoV-2-RNA Detection from Nasopharyngeal Swabs in an Oncologic Patient: What Impact on Cancer Treatment?

2021 ◽  
Vol 28 (1) ◽  
pp. 847-852
Author(s):  
Anna Ferrari ◽  
Marco Trevenzoli ◽  
Lolita Sasset ◽  
Elisabetta Di Liso ◽  
Toni Tavian ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Treatment ◽  
Cancer Patients ◽  
Clinical Symptoms ◽  
Palliative Radiotherapy ◽  
Rt Pcr ◽  
Cancer Treatments ◽  
Global Challenge ◽  
Viral Culture ◽  
Pcr Assays

The pandemic of SARS-CoV-2 is a serious global challenge affecting millions of people worldwide. Cancer patients are at risk for infection exposure and serious complications. A prompt diagnosis of SARS-CoV-2 infection is crucial for the timely adoption of isolation measures and the appropriate management of cancer treatments. In lung cancer patients the symptoms of infection 19 may resemble those exhibited by the underlying oncologic condition, possibly leading to diagnostic overlap and delays. Moreover, cancer patients might display a prolonged positivity of nasopharyngeal RT-PCR assays for SARS-CoV-2, causing long interruptions or delay of cancer treatments. However, the association between the positivity of RT-PCR assays and the patient’s infectivity remains uncertain. We describe the case of a patient with non-small cell lung cancer, and a severe ab extrinseco compression of the trachea, whose palliative radiotherapy was delayed because of the prolonged positivity of nasopharyngeal swabs for SARS-CoV-2. The patient did not show clinical symptoms suggestive of active infection, but the persistent positivity of RT-PCR assays imposed the continuation of isolation measures and the delay of radiotherapy for over two months. Finally, the negative result of SARS-CoV-2 viral culture allowed us to verify the absence of viral activity and to rule out the infectivity of the patient, who could finally continue her cancer treatment.

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