Novel risk factors and management of brain sag after brain tumor surgery

Abstract Hypoalbuminemia is associatied with poor outcome in patients undergoing surgery intervention. The main aim for this study was to investigate the incidence and the risk factors of postoperative hypoalbuminemia and assessed the impact of postoperative hypoalbuminemia on complications in patients undergoing brain tumor surgery. This retrospective study included 372 consecutive patients who underwent brain tumors surgery from January 2017 to December 2019. The patients were divided into hypoalbuminemia (< 35 g/L) and non-hypoalbuminemia group (≥ 35 g/L) based on postoperative albumin levels. Logistic regression analyses were used to determine risk factors. Of the total 372 patients, 333 (89.5%) developed hypoalbuminemia after surgery. Hypoalbuminemia was associated with operation time (OR 1.011, P < 0.001), preoperative albumin (OR 0.864, P = 0.015) and peroperative globulin (OR 1.192, P = 0.004). Postoperative pneumonia had a higher incidence in patients with than without hypoalbuminemia (41.1% vs 23.1%, P = 0.029). The independent predictors of postoperative pneumonia were age (OR 1.053, P < 0.001), operation time (OR 1.003, P = 0.013) and lower postoperative albumin (OR 0.946, P = 0.018). Postoperative hypoalbuminemia has a higher incidence with the increase of operation time, and is associated with postoperative pneumonia in patients undergoing brain tumor surgery.

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Suicidal ideation in patients undergoing brain tumor surgery: prevalence and risk factors

Supportive Care in Cancer ◽

10.1007/s00520-016-3117-2 ◽

2016 ◽

Cited By ~ 4

Author(s):

Aiste Pranckeviciene ◽

Sarunas Tamasauskas ◽

Vytenis Pranas Deltuva ◽

Robertas Bunevicius ◽

Arimantas Tamasauskas ◽

...

Keyword(s):

Risk Factors ◽

Brain Tumor ◽

Suicidal Ideation ◽

Tumor Surgery ◽

Brain Tumor Surgery

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Risk factors affecting the length of intensive care unit stay after brain tumor surgery

The Indian Anaesthetists Forum ◽

10.4103/theiaforum.theiaforum_14_19 ◽

2019 ◽

Vol 20 (2) ◽

pp. 61

Author(s):

Selda Kayaaltı ◽

Omer Kayaaltı

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Brain Tumor ◽

Intensive Care Unit Stay ◽

Tumor Surgery ◽

Brain Tumor Surgery ◽

Factors Affecting

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Association between postoperative hypoalbuminemia and postoperative pulmonary imaging abnormalities patients undergoing craniotomy for brain tumors: a retrospective cohort study

Scientific Reports ◽

10.1038/s41598-021-00261-2 ◽

2022 ◽

Vol 12 (1) ◽

Author(s):

Da-wei Zhao ◽

Feng-chun Zhao ◽

Xu-yang Zhang ◽

Kai-yan Wei ◽

Yi-bin Jiang ◽

...

Keyword(s):

Risk Factors ◽

Brain Tumor ◽

Brain Tumors ◽

Operation Time ◽

Tumor Surgery ◽

Regression Analyses ◽

Brain Tumor Surgery ◽

Pulmonary Imaging ◽

The Impact ◽

Preoperative Albumin

AbstractHypoalbuminemia is associated with poor outcome in patients undergoing surgery intervention. The main aim for this study was to investigate the incidence and the risk factors of postoperative hypoalbuminemia and assessed the impact of postoperative hypoalbuminemia on complications in patients undergoing brain tumor surgery. This retrospective study included 372 consecutive patients who underwent brain tumors surgery from January 2017 to December 2019. The patients were divided into hypoalbuminemia (< 35 g/L) and non-hypoalbuminemia group (≥ 35 g/L) based on postoperative albumin levels. Logistic regression analyses were used to determine risk factors. Of the total 372 patients, 333 (89.5%) developed hypoalbuminemia after surgery. Hypoalbuminemia was associated with operation time (OR 1.011, P < 0.001), preoperative albumin (OR 0.864, P = 0.015) and peroperative globulin (OR 1.192, P = 0.004). Postoperative pulmonary imaging abnormalities had a higher incidence in patients with than without hypoalbuminemia (41.1% vs 23.1%, P = 0.029). The independent predictors of postoperative pulmonary imaging abnormalities were age (OR 1.053, P < 0.001), operation time (OR 1.003, P = 0.013) and lower postoperative albumin (OR 0.946, P = 0.018). Pulmonary imaging abnormalities [OR 19.862 (95% CI 2.546–154.936, P = 0.004)] was a novel independent predictors of postoperative pneumonia. Postoperative hypoalbuminemia has a higher incidence with the increase of operation time, and may be associated with postoperative complications in patients undergoing brain tumor surgery.

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Postoperative Hematoma Requiring Recraniotomy in 1149 Consecutive Patients With Intracranial Tumors

Operative Neurosurgery ◽

10.1093/ons/opw045 ◽

2017 ◽

Vol 13 (3) ◽

pp. 392-397 ◽

Cited By ~ 6

Author(s):

Teruyoshi Kageji ◽

Shinji Nagahiro ◽

Yoshifumi Mizobuchi ◽

Kohei Nakajima

Keyword(s):

Risk Factors ◽

Brain Tumor ◽

Mortality Rate ◽

Operative Time ◽

Tumor Surgery ◽

Intracranial Tumors ◽

Brain Tumor Surgery ◽

Postoperative Hematoma ◽

Secondary Bleeding ◽

Infratentorial Tumors

Abstract BACKGROUND: The reported 30-day mortality rate after brain tumor surgery is 2.2% to 2.9%, with a postoperative hematoma (POH) as the most frequent cause of death. OBJECTIVE: To investigate the risk factors for a POH requiring a recraniotomy after brain tumor surgery in a large, contemporary, single-institution consecutive series. METHODS: We included 1149 patients who underwent surgery for intracranial tumors at the Tokushima University Hospital from 1997 to 2014. The patient charts were retrospectively studied from our prospectively collected database. We analyzed the risk factors, type of hemorrhage, time to reoperation, and outcomes. RESULTS: The incidence of a POH requiring a recraniotomy was 2.09%. Among the patients with a POH requiring a recraniotomy, 12.5% died within 30 days of the first surgery. The incidence of a POH requiring a recraniotomy significantly correlated with the incidence of a hemangioblastoma, infratentorial tumors, and a prolonged operative time (>10 h), but not with the patient age or sex, surgical procedure (biopsy or craniotomy), surgical type (primary or secondary), bleeding volume, or intraoperative blood transfusion requirement. A recraniotomy for a POH was performed in 54% of the patients just after the first operation, and within 24 h for 79% of the patients. The clinical status at the time of discharge deteriorated in 52% of the patients. CONCLUSION: Hemangioblastomas, infratentorial tumors, and an operative time exceeding 10 h were significantly correlated with an increased risk of a POH; these factors were responsible for 12.5% of the 30-day surgical mortality rate.

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