Familial hypercholesterolemia related admission for acute coronary syndrome in the United States: Incidence, predictors, and outcomes

2021 ◽  
Author(s):  
Babikir Kheiri ◽  
Timothy F Simpson ◽  
Mohammed Osman ◽  
Sudarshan Balla ◽  
Hind Rahmouni ◽  
...  
Keyword(s):  
United States ◽  
Acute Coronary Syndrome ◽  
Familial Hypercholesterolemia ◽  
The United States ◽  
Coronary Syndrome

scholarly journals Changes in mortality on weekend versus weekday admissions for Acute Coronary Syndrome in the United States over the past decade

2016 ◽  
Vol 210 ◽  
pp. 164-172 ◽  
Author(s):  
Mahdi Khoshchehreh ◽  
Elliott M. Groves ◽  
David Tehrani ◽  
Alpesh Amin ◽  
Pranav M. Patel ◽  
...  
Keyword(s):  
United States ◽  
Acute Coronary Syndrome ◽  
The United States ◽  
Coronary Syndrome ◽  
The Past

Photonic Crystal Sensors for the Rapid Detection of Myocardial Ischemia

2007 ◽  
Author(s):  
Justin T. Baca ◽  
David N. Finegold ◽  
Sanford A. Asher
Keyword(s):  
United States ◽  
Coronary Heart Disease ◽  
Acute Coronary Syndrome ◽  
Myocardial Ischemia ◽  
Rapid Detection ◽  
Biochemical Markers ◽  
Hospital Admissions ◽  
Rapid Test ◽  
The United States ◽  
Coronary Syndrome

Coronary Heart Disease is the leading cause of death in the United States and was responsible for approximately one of every five deaths in 2003 [1]. Unnecessary admissions to US Hospitals of patients with suspected Acute Coronary Syndrome (ACS) is estimated to cost about 12 billion dollars a year [2]. The earliest biochemical markers currently assayed do not appear in the blood for hours after the onset of chest pain; a rapid test for myocardial ischemia would help to expedite treatment and avoid unnecessary hospital admissions [3].

P3611The effect of concomitant AF on in-hospital clinical outcomes of NSTE-ACS related hospitalizations in the United States: an analysis of rates, trends and predictors from 2004 to 2014

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M O Mohamed ◽  
P Kirchhof ◽  
M Vidovich ◽  
M Savage ◽  
M Rashid ◽  
...  
Keyword(s):  
United States ◽  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Sinus Rhythm ◽  
Clinical Outcomes ◽  
The United States ◽  
Cardiac Complications ◽  
Adjusted Relative Risk ◽  
Coronary Syndrome ◽  
To Receive

Abstract Background Atrial fibrillation (AF) is the most common arrhythmia in patients presenting with acute coronary syndrome (ACS). Purpose We sought to examine the rates, trends, and clinical outcomes of non-ST Elevation acute coronary syndrome (NSTE-ACS) related hospitalisations in the United States in patients with AF compared to those with sinus rhythm (SR). Methods We analysed the Nationwide Inpatient Sample (NIS) database from 2004 to 2014 for patients with a primary discharge diagnosis of NSTEMI or UA, and further stratified the cohort on the basis of diagnoses into SR and AF groups. Multivariate analysis was performed to identify the association between AF and MACCE (composite of mortality, stroke and cardiac complications), mortality, stroke, and bleeding. Results A total of 4,668,737 NSTE-ACS admissions were included in our analysis. The proportions of SR and AF groups were 82.4% (3,848,202) and 17.6% (820,535), respectively. The incidence of AF increased significantly over time from 16.5% in 2004 to 19.3% in 2014 (p<0.001). The AF group was at a greater risk of adverse outcomes with higher overall rates and adjusted relative risk of MACCE (12.9% vs. 5.3%; RR: 1.74 [1.72, 1.75]), mortality (6.5% vs. 3.3%. RR: 1.12 [1.11, 1.13]), stroke (2.7% vs. 1.5%; RR: 1.32 [1.30, 1.34]) and bleeding (14.7% vs. 8.8%; RR: 1.42 [1.41, 1.43]). The AF group was less likely to receive coronary angiography (47.1% vs. 58%) and PCI (18.7% vs. 32.6%) and more likely to undergo CABG (13.9% vs. 7.6%) in comparison to SR. Figure 1. Crude rates of adverse events Conclusion The prevalence of concomitant Atrial Fibrillation amongst patients presenting with NSTE-ACS has increased over a decade. However, this high-risk group remains less likely to receive invasive coronary management for NSTE-ACS than patients with sinus rhythm, independent of their comorbidities, and are associated with worse clinical outcomes.

Sign in / Sign up

Export Citation Format

Share Document