Increased risk of depression in Bell's palsy: Two longitudinal follow-up studies using a national sample cohort

ObjectiveTo investigate the bidirectional association between migraine and rheumatoid arthritis (RA).DesignTwo longitudinal follow-up studies.SettingData collected from a national cohort between 2002 and 2013 by the Korean National Health Insurance Service-Health Screening Cohort.ParticipantsIn cohort 1, matching resulted in the inclusion of 31 589 migraine patients and 126 356 control I participants. In cohort 2, matching resulted in the inclusion of 9287 RA patients and 37 148 control II participants.Primary and secondary outcome measuresThe HRs for RA in patients with migraine (cohort 1) and migraine in patients with RA (cohort 2) were analysed using stratified Cox proportional hazard models after adjusting for autoimmune disease, Charlson Comorbidity Index scores without rheumatoid diseases, obesity (body mass index), smoking and history of alcohol intake. Subgroup analyses stratified by age, sex, income and region of residence were also performed.ResultsThe incidence of RA in the migraine group (2.0% (640/31 589)) was higher than that in the control I group (1.4% (1709/126 356), p<0.001). The adjusted HR for RA in the migraine without aura group was 1.48 (95% CIs=1.34 to 1.63, p<0.001).The incidence of migraine in the RA group (6.4% (590/9287)) was higher than that in the control II group (4.6% (1721/37 148), p<0.001). The adjusted HR for migraine without aura in the RA group was 1.35 (95% CI=1.23 to 1.49, p<0.001).ConclusionMigraine increases the risk of RA, and RA is also associated with an increased risk of migraine.

Download Full-text

Increased risk of peripheral arterial occlusive disease in patients with Bell's palsy using population data

PLoS ONE ◽

10.1371/journal.pone.0188982 ◽

2017 ◽

Vol 12 (12) ◽

pp. e0188982 ◽

Cited By ~ 1

Author(s):

Li-Syue Liou ◽

Chih-Ya Chang ◽

Hsuan-Ju Chen ◽

Chun-Hung Tseng ◽

Cheng-Yu Chen ◽

...

Keyword(s):

Peripheral Arterial Occlusive Disease ◽

Population Data ◽

Bell’S Palsy ◽

Arterial Occlusive Disease ◽

Occlusive Disease ◽

Bell's Palsy ◽

Increased Risk ◽

Peripheral Arterial

Download Full-text

Psoriasis is associated with an increased risk of osteoporosis: follow-up and nested case–control studies using a national sample cohort

Osteoporosis International ◽

10.1007/s00198-020-05724-2 ◽

2020 ◽

Author(s):

J.W. Lee ◽

C. Min ◽

C.H. Bang ◽

B.C. Kwon ◽

H.G. Choi

Keyword(s):

National Sample ◽

Case Control ◽

Case Control Studies ◽

Increased Risk ◽

Nested Case Control

Download Full-text

Bell paralizisi: Tanı, tedavi ve klinik takibi / Bell‘s palsy: diagnosis, treatment and clinical follow up

Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy ◽

10.5350/btdmjb201107203 ◽

2011 ◽

pp. 56-59

Author(s):

Cüneyt Kucur ◽

Arzu Baştürk ◽

Ali Okan Gürsel

Keyword(s):

Bell’S Palsy ◽

Bell's Palsy

Download Full-text

The Potential Role of Human Papillomavirus Infection in Bell's Palsy: A Hypothesis-Generating Study Based on a Nationwide Cohort

Frontiers in Medicine ◽

10.3389/fmed.2021.616873 ◽

2021 ◽

Vol 8 ◽

Author(s):

Kuan-Ying Li ◽

Mei-Chia Chou ◽

Renin Chang ◽

Hei-Tung Yip ◽

Yao-Min Hung ◽

...

Keyword(s):

Human Papillomavirus ◽

Index Date ◽

Hpv Infection ◽

Bell’S Palsy ◽

Sensitivity Analyses ◽

Chronic Obstructive ◽

Bell's Palsy ◽

Increased Risk ◽

The Impact

Objective: Our purpose was to investigate whether people with a previous human papillomavirus (HPV) infection were associated with an increased risk of Bell's palsy (BP).Methods: By using Taiwan population-based data, patients aged > 18 years with HPV infection (n = 22,260) from 2000 to 2012 were enrolled and compared with control subjects who had never been diagnosed with an HPV infection at a 1:4 ratio matched by sex, age, index date, and co-morbidities (n = 89,040). The index date was the first date of HPV diagnosis. All the patients were tracked until the occurrence of BP. Cox proportional hazards regression was applied to estimate the hazard ratios (HRs) for the development of BP in both groups.Results: The HPV group had 1.25 [95% confidence interval (CI) = 1.03–1.51] times higher risk of BP compared with the non-HPV group after adjusting for sex, age, and co-morbidities. The association of HPV and BP was significant in the sensitivity analyses. In the subgroup analysis, the impact of HPV infection on the risk of BP was more pronounced in the elderly > 50 years [adjusted hazard ratio (aHR) =1.86; 95% CI = 1.37–2.52], hypertension (aHR = 1.65; 95% CI = 1.17–2.31), and chronic obstructive pulmonary disease (aHR = 2.14, 95% CI 1.333.43) subgroups.Conclusions: Patients with HPV infection have a higher risk of subsequent BP compared with non-HPV patients. More rigorous studies are needed to confirm if and how specific HPV genotypes are associated with BP and the possible role of vaccines in disease prevention.

Download Full-text

A retrospective study on management of bell\'s palsy in a tertiary care hospital

Panacea Journal of Medical Sciences ◽

10.18231/j.pjms.2021.038 ◽

2021 ◽

Vol 11 (2) ◽

pp. 173-176

Author(s):

P.K Purushothaman ◽

Dhanyan Harshidan ◽

Priyangha Elangovan

Keyword(s):

Clinical Symptoms ◽

Tertiary Care ◽

Bell’S Palsy ◽

Care Hospital ◽

Bell's Palsy ◽

College Hospital ◽

Medical College ◽

Therapeutic Measures

Bell's palsy is the most common facial nerve disorder. The clinical symptoms of Bell's palsy include facial muscle paralysis, difficulty in eating, drinking and talking. Bell's palsy management is still controversial. Many patients recover spontaneously; some require medicines like corticosteroids, antiviral drugs and other managements.To study the effectiveness of Bell's palsy management that has been followed in our institution.This analysis had carried out from June 2016 to June 2019at SRM Medical College Hospital and Research Institute, Chennai. Total of 30 patients with Bell's palsy who had admitted in the Department of Otorhinolaryngology had enrolled in this study. All the patients underwent thorough clinical examination and laboratory investigation, and the results were statistically analyzed and discussed.Out of 30 patients, 16(53%) patients were males, and 14(47%) patients were females. 53.3% of patients had onset of symptoms after 48 hours. There was a statistical significant improvement in House-Brackman scale on 6 months follow-up.The therapeutic measures for Bell's palsy if initiated within 72 hours of onset aids in bringing better outcome and improves the quality of life in patients.

Download Full-text

Long-term glycemic variability and risk of stroke in patients with diabetes: a meta-analysis

Diabetology & Metabolic Syndrome ◽

10.1186/s13098-021-00770-0 ◽

2022 ◽

Vol 14 (1) ◽

Author(s):

Xiaoli Ren ◽

Zhiyun Wang ◽

Congfang Guo

Keyword(s):

Standard Deviation ◽

Coefficient Of Variation ◽

Meta Analysis ◽

Glycemic Variability ◽

Diabetic Patients ◽

Increased Risk ◽

Follow Up Studies ◽

Patients With Diabetes

Abstract Objectives Long-term glycemic variability has been related to increased risk of vascular complication in patients with diabetes. However, the association between parameters of long-term glycemic variability and risk of stroke remains not fully determined. We performed a meta-analysis to systematically evaluate the above association. Methods Medline, Embase, and Web of Science databases were searched for longitudinal follow-up studies comparing the incidence of stroke in diabetic patients with higher or lower long-term glycemic variability. A random-effect model incorporating the potential heterogeneity among the included studies were used to pool the results. Results Seven follow-up studies with 725,784 diabetic patients were included, and 98% of them were with type 2 diabetes mellitus (T2DM). The mean follow-up duration was 7.7 years. Pooled results showed that compared to those with lowest category of glycemic variability, diabetic patients with the highest patients had significantly increased risk of stroke, as evidenced by glycemic variability analyzed by fasting plasma glucose coefficient of variation (FPG-CV: risk ratio [RR] = 1.24, 95% confidence interval [CI] 1.11 to 1.39, P < 0.001; I2 = 53%), standard deviation of FPG (FPG-SD: RR = 1.16, 95% CI 1.02 to 1.31, P = 0.02; I2 = 74%), HbA1c coefficient of variation (HbA1c-CV: RR = 1.88, 95% CI 1.61 to 2.19 P < 0.001; I2 = 0%), and standard deviation of HbA1c (HbA1c-SD: RR = 1.73, 95% CI 1.49 to 2.00, P < 0.001; I2 = 0%). Conclusions Long-term glycemic variability is associated with higher risk of stroke in T2DM patients.

Download Full-text