Impactor designed to increase mass output rate of nanoparticles from a pneumatic nebulizer

2010 ◽  
Vol 41 (2) ◽  
pp. 170-179 ◽  
Author(s):  
Dane A. Boysen ◽  
Thomas M. Peters
2020 ◽  
Vol 1099 ◽  
pp. 16-25 ◽  
Author(s):  
Daniel Rosenkranz ◽  
Fabian L. Kriegel ◽  
Emmanouil Mavrakis ◽  
Spiros A. Pergantis ◽  
Philipp Reichardt ◽  
...  

2010 ◽  
Vol 450 ◽  
pp. 365-368
Author(s):  
James C. Chen ◽  
Chia Wen Chen ◽  
Kou Huang Chen ◽  
Chien Hsin Lin

Wafer fabrication is a capital intensive industry. A 12-inch wafer fabrication plant needs a typical investment of US$ 3 billion, and the equipment cost constitutes about two-thirds to three-quarters of the total production costs. Therefore, capacity planning is crucial to the investment and performance of wafer fabrication plants. Several formulae are presented to calculate the required number of machines with sequential, parallel, and batch processing characteristics, respectively. An AutoSched AP simulation model using data from real foundry fabrication plants is used in a case study to evaluate the performance of the proposed formulae. Simulation results indicate that the proposed formulae can quickly and accurately calculate the required number of cluster tools leading to the required monthly output rate.


2021 ◽  
Vol 25 (1) ◽  
pp. 124-149
Author(s):  
Alexandre Silva ◽  
José C. Sá ◽  
Gilberto Santos ◽  
Francisco J.G. Silva ◽  
Luís P. Ferreira ◽  
...  

Purpose: This study was carried out in a cork company and its purpose was to observe and analyze the practices and methods used during the tools/series change moments and to propose improvements and alternatives to these same procedures so that the time needed to carry out the setup is reduced by 15% in both lines. Methodology/Approach:The methodology included the following phases: 1st - historical data collection and setup video recording, 2nd - footage analysis and conduction of informal interviews with employees, 3rd - flow, Gantt, and spaghetti charts creation and making of an action plan based on the waste and improvement opportunities identified in video analysis, 4th - validation with the line workers of the new operating mode created with the Single Minute Exchange of Dies (SMED) tool and communication to the Maintenance department about their role in this project, 5th - making and placement of plasticized cards on the cutting lines to ensure that new operating mode is followed and carrying out the actions identified in the action plan. Findings: Throughout this project using observations, video recording and its subsequent analysis, as well as interviews to the workers operating in the line, it was found the existence of several actions carried out by them during the setups which did not add value to the product, lack of adequate tools for the work to be performed and lack of work tools in general Research Limitation/implication: The study was limited by the lines and products under study and by the duration of the curricular internship, which was about five months. Originality/Value of paper: The article demonstrates the added value in terms of product quality and production output rate that SMED methodology can bring to companies that adopt the lean philosophy and in particular this continuous improvement tool.


Metallurgist ◽  
1970 ◽  
Vol 14 (5) ◽  
pp. 295-297
Author(s):  
M. Ya. Medzhibozhskii ◽  
G. A. Rudakov ◽  
A. A. Lykin
Keyword(s):  

Pharmaceutics ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 192 ◽  
Author(s):  
Chang ◽  
Moon ◽  
Oh ◽  
Yoon ◽  
Gu ◽  
...  

Recent reports using a breathing simulator system have suggested that mesh nebulizers provide more effective medication delivery than jet nebulizers. In this study, the performances of jet and mesh nebulizers were evaluated by comparing their aerosol drug delivery efficiencies in mice. We compared four home nebulizers: two jet nebulizers (PARI BOY SX with red and blue nozzles), a static mesh nebulizer (NE-U22), and a vibrating mesh nebulizer (NE-SM1). After mice were exposed to salbutamol aerosol, the levels of salbutamol in serum and lung were estimated by ELISA. The residual volume of salbutamol was the largest at 34.6% in PARI BOY SX, while the values for NE-U22 and NE-SM1 mesh nebulizers were each less than 1%. The salbutamol delivery efficiencies of NE-U22 and NE-SM1 were higher than that of PARI BOY SX, as the total delivered amounts of lung and serum were 39.9% and 141.7% as compared to PARI BOY SX, respectively. The delivery efficiency of the mesh nebulizer was better than that of the jet nebulizer. Although the jet nebulizer can generate smaller aerosol particles than the mesh nebulizer used in this study, the output rate of the jet nebulizer is low, resulting in lower salbutamol delivery efficiency. Therefore, clinical validation of the drug delivery efficiency according to nebulizer type is necessary to avoid overdose and reduced drug wastage.


Diabetologia ◽  
1975 ◽  
Vol 11 (4) ◽  
pp. 291-299 ◽  
Author(s):  
U. Fischer ◽  
H. Hommel ◽  
H. D. Gottschling ◽  
P. Heinke ◽  
E. Jutzi

1993 ◽  
Author(s):  
Maria Simon ◽  
Paulo Villegas ◽  
Javier C. Caballero ◽  
Miguel Roser

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