P1-228: N-Back Task in Patients with Dementia and Depression Compared to Patients with Only Depression: Cardiovascular Pathology Without and with Diabetes Mellitus

Diabetes mellitus represents a serious medico-social problem that is caused by its high prevalence, a tendency to body height of number ofpatients, a high invalidism and a mortality. The main reason for death ofpatients with a diabetes mellitus type 2 is the pathology of cardiovascular system bound to an atherosclerosis to which leads lack of adequate compensation of a disease. In this article various risk factors of cardiovascular pathology at patients with a diabetes mellitus are surveyed and modern opportunities in their correction are discussed.

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The Relationship between the Acute Confusing State and the Comorbidities of the Elderly Patient

Revista de Chimie ◽

10.37358/rc.19.7.7352 ◽

2019 ◽

Vol 70 (7) ◽

pp. 2415-2419 ◽

Cited By ~ 1

Author(s):

Valeria Carmen Albu ◽

Raluca Elena Sandu ◽

Andreea Lili Barbulescu ◽

Elena-Anca Tartea ◽

Emilia Burada ◽

...

Keyword(s):

Diabetes Mellitus ◽

Elderly Patient ◽

Elderly Patients ◽

Neurological Examination ◽

The Elderly ◽

Cardiovascular Pathology ◽

Wide Range ◽

Neurology Clinic ◽

The Relationship ◽

Hepatic Pathology

The aim of the study was to assess the correlations between the acute confusing syndrome and different comorbidities found in a group of 126 elderly patients with this diagnosis, who were admitted to the Neurology Clinic of the Neuropsychiatry Hospital of Craiova. The main syndromes highlighted at the neurological examination were confusing, pyramidal and vestibular syndromes. The acute confusing syndrome has a multifactorial etiology, due to the wide range of comorbidities encountered in elderly patients. In our study the most frequent comorbidities were cardiovascular pathology, diabetes mellitus, dyslipidemia, cerebrovascular renal, hepatic pathology.

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P4-150: Cognitive performance of demented, depressed patients with cardiovascular pathology with and without diabetes mellitus: A preliminary report of a cross-sectional study

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1540 ◽

2013 ◽

Vol 9 ◽

pp. P759-P759

Author(s):

Valentin Bragin ◽

Gary Shereshevsky ◽

Ilya Bragin ◽

Arina Gorskaya ◽

Ryan Meylikh ◽

...

Keyword(s):

Diabetes Mellitus ◽

Cognitive Performance ◽

Preliminary Report ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Cardiovascular Pathology ◽

Depressed Patients

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The importance of glycemic control in patients with early forms of carbohydrate metabolism disorders in order to prevent type 2 diabetes mellitus and cardiovascular pathology

Consilium Medicum ◽

10.26442/20751753.2020.12.200191 ◽

2020 ◽

Vol 22 (12) ◽

pp. 57-62

Author(s):

Irina I. Kochergina ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Glycemic Control ◽

Carbohydrate Metabolism ◽

Vascular Complications ◽

Cardiovascular Complications ◽

Cardiovascular Pathology

The article presents data on the prevalence of diabetes and prediabetes; the high compatibility of diabetes mellitus and cardiovascular pathology; high mortality among patients with diabetes mellitus and coronary heart disease, in the presence of both acute and chronic cardiovascular complications; on the important role of glucose- and lipotoxicity in the progression of carbohydrate metabolism from prediabetes to type 2 diabetes mellitus, the role of hyperglycemia in the deve-lopment of insulin resistance, atherosclerosis, hypertension, liver, kidney, endothelial dysfunction, the role of hyper- and hypoglycemia in the development of acute vascular complications – myocardial infarction, stroke, gangrene of the lower extremities; on the protective role of adiponectin – a predictor of type 2 diabetes mellitus, on the importance of glycemic control for the timely detection of early disorders of carbohydrate metabolism – impaired glucose tolerance and impaired fasting glucose; on the role of metformin in the prevention of progression of prediabetes to type 2 diabetes and cardiac pathology; on the gluco- and cardioprotective role of modern sugar-lowering drugs.

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The role of mineral and bone metabolism disorders in the development and progression of cardiac and renal pathology in the patients presenting with long-lasting type 1 diabetes mellitus

Problems of Endocrinology ◽

10.14341/probl201359516-24 ◽

2013 ◽

Vol 59 (5) ◽

pp. 16-24

Author(s):

M S Biragova ◽

S A Gracheva ◽

A M Glazunova ◽

T I Dubrovskaia ◽

S A Martynov ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Renal Function ◽

Coronary Artery ◽

Coronary Artery Calcification ◽

Calcium Metabolism ◽

Agatston Score ◽

Cardiovascular Pathology ◽

Score Index

The present study included a total of 96 patients with long-lasting type 1 diabetes mellitus (DM1) and early (0-5) stages of chronic renal disease (CRD). Replacement renal therapy (RRT) consisted of programmed hemodialysis (PHD) and kidney transplantation (KT). Routine clinical examination was supplemented by the assessment of phosphorous and calcium metabolism indices, measurement of cardiac pathology markers, and studies of coronary artery calcification with the use of multispiral computed tomography (MSCT) of the heart with the calculation of the Agatston score index. It was shown that the impairment of the renal function was accompanied by a rise in the phosphorus, parathormone, and FGF-23 levels, increased vitamin D deficiency (with a slight deviation of its levels from the reference values in the patients at high risk of cardiovascular events treated with PHD). In the patients who had undergone KT and showed fairly good function of the renal transplant, the above parameters were similar to those of the patients with stage 0-4 CRD which suggested their normalization in case of adequate RRT during DM1. The progress of cardiovascular pathology with the deterioration of the renal function was manifested as an increase of NT-proBNP levels in parallel to the duration of CRD (r=0.304; p<0.05), decrease of the glomerular filtration rate (p=-0.540; p<0.05), and their significant correlation with the main characteristics of mineral homeostasis. The degree of coronary artery calcification was related to the patients' age, duration of DM1, and severity of arterial hypertension. The high Agatston score index and pronounced left ventricular hypertrophy in the patients following KT are supposed to reflect the irreversible character of certain cardiovascular lesions persisting despite optimal RRT and positive dynamics of phosphorus and calcium metabolism and NT-proBNP levels. It is concluded that the development and progression of renal dysfunction are associated with the disturbances of mineral and bone metabolism that promote further progress of cardiovascular pathology that is the main cause of mortality among this cohort of patients.

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An Easy Way to Detect Cardiovascular Risk

Revista de Chimie ◽

10.37358/rc.18.11.6741 ◽

2018 ◽

Vol 69 (11) ◽

pp. 3329-3332

Author(s):

Ionela Mihaela Vladu ◽

Lucretiu Radu ◽

Sigina Rodica Girgavu ◽

Vlad Baleanu ◽

Diana Clenciu ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Myocardial Infarction ◽

Cardiovascular Risk ◽

Metabolic Risk ◽

Chronic Ischemic Heart Disease ◽

Metabolic Factors ◽

Cardiovascular Pathology ◽

Clinical Consequences

Cardiovascular risk means the degree of risk for atherosclerotic cardiovascular pathology, predictable by quantifying the risk factors (RF) existing in each individual. Global cardio-metabolic risk is the overall risk of developing type 2 diabetes mellitus (T2DM) and/or CVD, including myocardial infarction (MI) and stroke, which is due to a bundle of risk factors. The cardio-metabolic risk is based on the concept of continuous risk. The importance of cardiovascular / cardio-metabolic risk is particular because controlling its components may affect atherogenesis and its clinical consequences: chronic ischemic heart disease, cerebrovascular disease and peripheral arteriopathy, but also diabetes mellitus (DM). Currently there is no method to use all the known risk cardio-metabolic factors to quantify cardiovascular risk or diabetes risk.

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