THE CHANGING FACE OF MILD COGNITIVE IMPAIRMENT (MCI) AND MILD DEMENTIA

2017 ◽  
Vol 13 (7) ◽  
pp. P544-P545
Author(s):  
Connor Richardson ◽  
Fiona Matthews ◽  
Louise Robinson ◽  
Blossom C.M. Stephan
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Mild Dementia

scholarly journals Relationship between Cognitive Performance and Measures of Neurodegeneration among Hispanic and White Non-Hispanic Individuals with Normal Cognition, Mild Cognitive Impairment, and Dementia

2017 ◽  
Vol 24 (2) ◽  
pp. 176-187 ◽  
Author(s):  
Shanna L. Burke ◽  
Miriam J. Rodriguez ◽  
Warren Barker ◽  
Maria T Greig-Custo ◽  
Monica Rosselli ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Performance ◽  
Entorhinal Cortex ◽  
Rating Scale ◽  
Structural Mri ◽  
Diagnostic Group ◽  
Disease Stage ◽  
Clinical Dementia Rating ◽  
Mild Dementia

AbstractObjectives:The aim of this study was to determine the presence and severity of potential cultural and language bias in widely used cognitive and other assessment instruments, using structural MRI measures of neurodegeneration as biomarkers of disease stage and severity.Methods:Hispanic (n=75) and White non-Hispanic (WNH) (n=90) subjects were classified as cognitively normal (CN), amnestic mild cognitive impairment (aMCI) and mild dementia. Performance on the culture-fair and educationally fair Fuld Object Memory Evaluation (FOME) and Clinical Dementia Rating Scale (CDR) between Hispanics and WNHs was equivalent, in each diagnostic group. Volumetric and visually rated measures of the hippocampus entorhinal cortex, and inferior lateral ventricles (ILV) were measured on structural MRI scans for all subjects. A series of analyses of covariance, controlling for age, depression, and education, were conducted to compare the level of neurodegeneration on these MRI measures between Hispanics and WNHs in each diagnostic group.Results:Among both Hispanics and WNH groups there was a progressive decrease in volume of the hippocampus and entorhinal cortex, and an increase in volume of the ILV (indicating increasing atrophy in the regions surrounding the ILV) from CN to aMCI to mild dementia. For equivalent levels of performance on the FOME and CDR, WNHs had greater levels of neurodegeneration than did Hispanic subjects.Conclusions:Atrophy in medial temporal regions was found to be greater among WNH than Hispanic diagnostic groups, despite the lack of statistical differences in cognitive performance between these two ethnic groups. Presumably, unmeasured factors result in better cognitive performance among WNH than Hispanics for a given level of neurodegeneration. (JINS, 2018,24, 176–187)

Development of a decision-making tool for reporting drivers with mild dementia and mild cognitive impairment to transportation administrators

2017 ◽  
Vol 29 (9) ◽  
pp. 1551-1563 ◽  
Author(s):  
Duncan H. Cameron ◽  
Carla Zucchero Sarracini ◽  
Linda Rozmovits ◽  
Gary Naglie ◽  
Nathan Herrmann ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Delphi Study ◽  
Qualitative Interviews ◽  
Decision Support Tool ◽  
Driving Safety ◽  
Decision Tool ◽  
Computerized Decision Support ◽  
Support Tool ◽  
Mild Dementia

ABSTRACTBackground:Driving in persons with dementia poses risks that must be counterbalanced with the importance of the care for autonomy and mobility. Physicians often find substantial challenges in the assessment and reporting of driving safety for persons with dementia. This paper describes a driving in dementia decision tool (DD-DT) developed to aid physicians in deciding when to report older drivers with either mild dementia or mild cognitive impairment to local transportation administrators.Methods:A multi-faceted, computerized decision support tool was developed, using a systematic literature and guideline review, expert opinion from an earlier Delphi study, as well as qualitative interviews and focus groups with physicians, caregivers of former drivers with dementia, and transportation administrators. The tool integrates inputs from the physician-user about the patient's clinical and driving history as well as cognitive findings, and it produces a recommendation for reporting to transportation administrators. This recommendation is translated into a customized reporting form for the transportation authority, if applicable, and additional resources are provided for the patient and caregiver.Conclusions:An innovative approach was needed to develop the DD-DT. The literature and guideline review confirmed the algorithm derived from the earlier Delphi study, and barriers identified in the qualitative research were incorporated into the design of the tool.

scholarly journals Cognitive Outcomes during COVID-19 confiNemeNt in Elderly and their Caregivers using Technologies for DEMentia (CONNECT DEM): study protocol (Preprint)

2020 ◽  
Author(s):  
Jessica Marian Goodman-Casanova ◽  
Elena Dura-Perez ◽  
Gloria Guerrero-Pertiñez ◽  
Pilar Barnestein-Fonseca ◽  
Jose Guzman-Parra ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Social Isolation ◽  
Community Dwelling ◽  
Mild Dementia ◽  
Care Services ◽  
Health And Social Care ◽  
The Impact ◽  
Community Dwelling Older Adults

BACKGROUND Coronavirus disease 2019 has forced worldwide the implementation of unprecedented restrictions to control its rapid spread and mitigate its impact. The Spanish government has enforced social distancing, quarantine and home confinement. This restriction of daily life activities and separation from loved ones may lead to social isolation and loneliness with health-related consequences in community-dwelling older adults with mild cognitive impairment or mild dementia and their caregivers. Additionally, an inadequate access to healthcare and social support services may aggravate chronic conditions. Technology home-based interventions emerge for combating social isolation and loneliness preventing the risk of viral exposure. OBJECTIVE The aim of this cohort study is to explore, analyze and determine the impact of social isolation on: 1) cognition, quality of life, mood, technophilia and perceived stress of community-dwelling older adults with mild cognitive impairment or mild dementia, and on caregiver burden; 2) health and social care services access and utilization, and 3) cognitive, social and entertainment use of ICTs. METHODS This study will be conducted in the Spanish region of Andalucía (Málaga). In total 200 dyads, consisting of a person with mild cognitive impairment or mild dementia (PMCI/MD) and their informal caregiver will be contacted by telephone. Potential respondents will be participants of the SMART 4 MD (N=100) and TV-AssistDem (N=100) clinical trials. RESULTS The change in means in the variables will be analyzed comparing baseline results in the previous studies with those during and after confinement using the ANOVA test of repeated measures or the non-parametric Friedman test if appropriate. The performance of a multivariate analysis of variance (ANCOVA) to introduce possible covariates will also be contemplated. A 95% confidence level will be used. CONCLUSIONS If the hypothesis is proven, these findings will demonstrate the negative impact of social isolation due to the COVID-19 confinement on cognition, quality of life, mood, and perceived stress of community-dwelling older adults with mild cognitive impairment and mild dementia, the impact on technophilia, caregiver burden, and health and social care services access and utilization; and the cognitive, social and entertainment use of ICTs during the COVID-19 confinement and afterwards. CLINICALTRIAL NCT: 04385797

scholarly journals Association of Lower Spiritual Well-Being, Social Support, Self-Esteem, Subjective Well-Being, Optimism and Hope Scores With Mild Cognitive Impairment and Mild Dementia

2018 ◽  
Vol 9 ◽  
Author(s):  
Sabrina B. dos Santos ◽  
Gabrielli P. Rocha ◽  
Liana L. Fernandez ◽  
Analuiza C. de Padua ◽  
Caroline T. Reppold
Keyword(s):  
Social Support ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Well Being ◽  
Self Esteem ◽  
Subjective Well Being ◽  
Mild Dementia ◽  
Spiritual Well Being

Technology use to improve everyday occupations in older persons with mild dementia or mild cognitive impairment: A scoping review

2018 ◽  
Vol 81 (10) ◽  
pp. 555-565 ◽  
Author(s):  
Ann-Helen Patomella ◽  
Meryl Lovarini ◽  
Eva Lindqvist ◽  
Anders Kottorp ◽  
Louise Nygård
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Scoping Review ◽  
Technology Use ◽  
Older Persons ◽  
Mild Dementia

scholarly journals P4-640: DISEASE PROGRESSION AND COSTS AT 1-YEAR FOLLOW-UP OF GERAS-US: A 3-YEAR STUDY OF MILD COGNITIVE IMPAIRMENT AND MILD DEMENTIA DUE TO ALZHEIMER'S DISEASE IN THE UNITED STATES

2019 ◽  
Vol 15 ◽  
pp. P1574-P1574
Author(s):  
Julie Chandler ◽  
Anthony Zagar ◽  
Yongin Kim ◽  
Brandy R. Matthews ◽  
Rebecca L. Robinson ◽  
...  
Keyword(s):  
United States ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Disease Progression ◽  
The United States ◽  
Mild Dementia

[P3-291]: CHOLINESTERASE INHIBITOR USE AND COGNITIVE DECLINE IN MILD COGNITIVE IMPAIRMENT AND MILD DEMENTIA DUE TO ALZHEIMER DISEASE

2017 ◽  
Vol 13 (7S_Part_22) ◽  
pp. P1054-P1054 ◽  
Author(s):  
Jee-young Han ◽  
Lilah M. Besser ◽  
Chengjie Xiong ◽  
Walter A. Kukull ◽  
John C. Morris
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Cognitive Decline ◽  
Cholinesterase Inhibitor ◽  
Mild Dementia

P2-149: The Mini-Mental State Examination gradient in community healthy elderly subjects, mild cognitive impairment and mild dementia

2010 ◽  
Vol 6 ◽  
pp. S357-S357
Author(s):  
Lívia G. Rodrigues ◽  
Ana Luiza Camozzato ◽  
Renata Kochhann ◽  
Claudia Godinho ◽  
Maria Otilia Cerveira ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Elderly Subjects ◽  
Mild Dementia ◽  
Healthy Elderly ◽  
State Examination ◽  
Healthy Elderly Subjects

P2-254: An educational memory course for patients suffering from mild cognitive impairment or mild dementia

2008 ◽  
Vol 4 ◽  
pp. T446-T446
Author(s):  
Jytte Dock ◽  
Birgitte Bo Andersen ◽  
Gunhild Waldemar
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Mild Dementia
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