P3-538: EFFICACY OF REGULATED COGNITIVE TRAINING IN SUBJECTS WITH SUBJECTIVE MEMORY COMPLAINTS: A PROSPECTIVE LONGITUDINAL CONTROLLED STUDY

Subjective memory complaints (SMCs) may be important markers in the prediction of cognitive deterioration. The aim of this study was to find associations between individual lifestyle factors, which may contribute to cognitive impairment (CI) in people with SMCs and to conduct a literature review on the relationship between internet use and CI in subjects over 50 years old, as a related factor. This was a case-controlled study that included 497 subjects aged over 50 years with SMCs who were recruited from 19 community pharmacies. Three screening tests were used to detect possible CIs, and individuals with at least one test result compatible with a CI were referred to primary care for evaluation. Having self-referred SMC increased the odds of obtaining scores compatible with CI and this factor was significantly related to having feelings of depression (OR = 2.24, 95% CI [1.34, 3.90]), taking anxiolytics or antidepressants (OR = 1.93, 95% CI [1.23, 3.05]), and being female (OR = 1.83, 95% CI [1.15, 2.88]). Thirty percent of our sample obtained scores compatible with CI. Age over 70 years increased the odds of obtaining scores compatible with CI. A high-level education, reading, and daily internet use were factors associated with a reduced risk of positive scores compatible with CI (37–91%, 7–18%, and 67–86%, respectively), while one extra hour television per day increased the risk by 8–30%. Among others, modifiable lifestyle factors such as reading, and daily internet usage may slow down cognitive decline in patients over 50 with SMCs. Four longitudinal studies and one quasi-experimental study found internet use to be beneficial against CI in patients over 50 years of age.

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Efficacy of a computer-based cognitive training program in older people with subjective memory complaints: a randomized study

International Journal of Neuroscience ◽

10.1080/00207454.2017.1308930 ◽

2017 ◽

Vol 128 (1) ◽

pp. 1-9 ◽

Cited By ~ 6

Author(s):

Angela J. Pereira-Morales ◽

Andres F. Cruz-Salinas ◽

Jairo Aponte ◽

Francisco Pereira-Manrique

Keyword(s):

Older People ◽

Training Program ◽

Cognitive Training ◽

Randomized Study ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Memory Complaints ◽

Computer Based

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An ERP study on facial emotion processing in young people with subjective memory complaints

Scientific Reports ◽

10.1038/s41598-021-90861-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Vanesa Perez ◽

Ruth Garrido-Chaves ◽

Mario Perez-Alarcón ◽

Tiago O. Paiva ◽

Matias M. Pulopulos ◽

...

Keyword(s):

Young People ◽

Early Stage ◽

Emotion Processing ◽

Affective State ◽

Event Related Potential ◽

Facial Emotion ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Memory Complaints ◽

Facial Emotion Processing

AbstractSubjective memory complaints (SMCs) are commonly related to aging, but they are also presented by young adults. Their neurophysiological mechanisms are not thoroughly understood, although some aspects related to affective state have been mentioned. Here, we investigated whether facial emotion processing is different in young people with (n = 41) and without (n = 39) SMCs who were exposed to positive, negative, and neutral faces, by recording the event-related potential (ERP) activity. From the ERP activity, the N170 (an index of face processing) and the LPP (an index of motivated attention) components were extracted. Regarding the N170, results showed less amplitude for positive and neutral faces in the participants with SMCs than in those without SMCs. Moreover, women with SMCs displayed longer latencies for neutral faces than women without SMCs. No significant differences were found between the groups in the LPP component. Together, our findings suggest deficits in an early stage of facial emotion processing in young people with SMCs, and they emphasize the importance of further examining affective dimensions.

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Z-score neurofeedback, heart rate variability biofeedback, and brain coaching for older adults with memory concerns

Restorative Neurology and Neuroscience ◽

10.3233/rnn-201053 ◽

2020 ◽

pp. 1-29

Author(s):

Kyle D. Meeuwsen ◽

Kayleah M. Groeneveld ◽

Linda A. Walker ◽

Anna M. Mennenga ◽

Rachel K. Tittle ◽

...

Keyword(s):

Quality Of Life ◽

Boot Camp ◽

Relative Power ◽

Z Score ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Memory Complaints ◽

Anxiety Depression

Background: The three-month, multidomain Memory Boot Camp program incorporates z-score neurofeedback (NFB), heart rate variability (HRV) biofeedback, and one-on-one coaching to teach memory skills and encourage behavior change in diet, sleep, physical fitness, and stress reduction. Objective: This prospective trial evaluates the Memory Boot Camp program for adults ages 55 to 85 with symptoms of Mild Cognitive Impairment (MCI) and subjective memory complaints. Methods: Participants were evaluated via the Montreal Cognitive Assessment (MoCA), NeuroTrax Global Cognitive Index, measures of anxiety, depression, sleep, quality of life, quantitative electroencephalography (QEEG), and HRV parameters at four timepoints: baseline, pre-program, post-program, and follow-up. The trial included a three-month waiting period between baseline and pre-program, such that each participant acted as their own control, and follow-up took place six months after completion of the program. Results: Participants’ MoCA scores and self-reported measures of anxiety, depression, sleep quality, and quality of life improved after treatment, and these changes were maintained at follow-up. Physiological changes in HRV parameters after treatment were not significant, however, breathing rate and QEEG parameters were improved at post-program and maintained at follow-up. Finally, participants’ improvement in MoCA score over the treatment period was correlated with their improvement in two brain oscillation parameters targeted by the z-score NFB protocol: relative power of delta and relative power of theta. Conclusions: Trial results suggest that the Memory Boot Camp program is a promising treatment strategy for older adults with symptoms of MCI and subjective memory complaints.

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