Risk of Death Associated With Use of PPIs in Three Cohorts of Institutionalized Older People in Finland

2012 ◽  
Vol 13 (5) ◽  
pp. 488.e9-488.e13 ◽  
Author(s):  
Mariko Teramura-Grönblad ◽  
J. Simon Bell ◽  
Minna M. Pöysti ◽  
Timo E. Strandberg ◽  
Jouko V. Laurila ◽  
...  
Keyword(s):  
Older People ◽  
Risk Of Death ◽  
Institutionalized Older People

scholarly journals Factors associated with inflamm-aging in institutionalized older people

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Leônidas de Oliveira Neto ◽  
Vagner Deuel de O. Tavares ◽  
Pedro Moraes Dutra Agrícola ◽  
Larissa Praça de Oliveira ◽  
Márcia Cristina Sales ◽  
...  
Keyword(s):  
Older People ◽  
Oldest Old ◽  
Bivariate Analysis ◽  
Older Individuals ◽  
Factors Associated ◽  
Risk Of Death ◽  
Health Related ◽  
Inflammatory State ◽  
Unit Of Measurement ◽  
Institutionalized Older People

AbstractThe increase in inflammatory cytokines associated with a reduction in the bioavailability of zinc has been used as a marker for inflammation. Despite the high inflammatory state found in institutionalized older individuals, few studies have proposed verifying the factors associated with this condition in this population. To verify the factors associated with inflamm-aging in institutionalized older people. A total of 178 older people (≥ 60 years old) living in nursing homes in Natal/RN were included in the study. Cluster analysis was used to identify three groups according to their inflammatory state. Analysis anthropometric, biochemical, sociodemographic, and health-related variables was carried out. In sequence, an ordinal logistic regression was performed for a confidence level of 95% in those variables with p < 0.20 in the bivariate analysis. IL-6, TNF-α, zinc, low-density lipids (LDL), high-density lipids (HDL), and triglycerides were associated with inflamm-aging. The increase of 1 unit of measurement of LDL, HDL, and triglycerides increased the chance of inflammation-aging by 1.5%, 4.1%, and 0.9%, respectively, while the oldest old (≥ 80 years old) had an 84.9% chance of presenting inflamm-aging in relation to non-long-lived older people (< 80 years). The association between biochemical markers and inflamm-aging demonstrates a relationship between endothelial injury and the inflammatory state. In addition, the presence of a greater amount of fat in the blood may present a higher relative risk of death.

scholarly journals Hip Fracture Causes Excess Mortality Due to Cardiovascular and Infectious Disease in Institutionalized Older People: A Prospective Five-Year Study

2009 ◽  
pp. 091019190442039-22 ◽  
Author(s):  
Ian D Cameron ◽  
Jian Sheng Chen ◽  
Lyn M March ◽  
Judy M Simpson ◽  
Robert G Cumming ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Hip Fracture ◽  
Older People ◽  
Excess Mortality ◽  
Institutionalized Older People

Influence of nutritional status on health-related quality of life of non-institutionalized older people

2013 ◽  
Vol 18 (4) ◽  
pp. 359-364 ◽  
Author(s):  
Susana Jiménez-Redondo ◽  
B. Beltran De Miguel ◽  
J. Gavidia Banegas ◽  
L. Guzman Mercedes ◽  
J. Gomez-Pavon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Older People ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Institutionalized Older People

Immediate physiological effects of listening to music before physical exercise in institutionalized older people with dementia

2021 ◽  
Vol 28 (3) ◽  
pp. 308-317
Author(s):  
Tamires Ferri Izzo ◽  
Maria Juana Beatriz Lima Candanedo ◽  
Aline Yumi Higuti ◽  
Lucas Magalhães Corrêa ◽  
Dayane Melo Campos ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Older People ◽  
Physiological Effects ◽  
Physiological Factors ◽  
Functional Changes ◽  
Positive Effects ◽  
The Third ◽  
Physical Exercises ◽  
People With Dementia ◽  
Institutionalized Older People

ABSTRACT The evolution of dementia is strongly related to cognitive, motor, and functional changes and to the presence of cardiovascular diseases. Disturbances vary according to phase of dementia and can limit instrumental and basic activities of daily living. The aim of this study was to analyze the immediate physiological effects of listening to music before physical exercise in institutionalized older people with moderate to advanced dementia. A randomized trial was conducted with 18 institutionalized older people with dementia (mean age was 79 years old, 52.6% were female), who were divided into a Training with Music Group (TWMG) and a Training without Music Group (TWtMG). The evaluation included heart rate (HR), blood pressure (BP) and HR variability (HRV). The assessment was conducted in a closed environment or in places with minimal visual and auditory stimulation. The TWMG was submitted to stimuli with music for 15 minutes and physical exercises for 30 minutes to improve/maintain their global mobility. The TWtMG performed the same physical exercises, however without music before physical exercise. The interventions lasted 12 weeks, and were performed individually once a week. In the TWMG, we observe a decrease in diastolic BP in the third session. In the sixth week, the HR increased after the session in both groups. TWMG improved HRV in the third session, with a difference between groups only after the session. After the sixth session, HRV values improved in both groups. In conclusion, listening to music before physical exercise is associated with positive effects in people with dementia, as it tends to maintain and improve physiological factors.

83 A Deficit Accumulation Frailty Index Predicts Mortality in Older South Africans: Findings from the HAALSI Study

2020 ◽  
Vol 49 (Supplement_1) ◽  
pp. i27-i27
Author(s):  
F J Barker ◽  
J I Davies ◽  
F X Gomez-Olive ◽  
K Kahn ◽  
F E Matthews ◽  
...  
Keyword(s):  
South Africa ◽  
Older People ◽  
Frailty Index ◽  
Cox Proportional Hazards ◽  
Sub Saharan Africa ◽  
Deficit Accumulation ◽  
South Africans ◽  
Risk Of Death ◽  
The Mean ◽  
Cumulative Deficit

Abstract Introduction Few studies have investigated frailty in older people in sub-Saharan Africa, yet such information is vital to prepare responses to rapid population ageing. We aimed to derive and test a cumulative deficit frailty index in a population of older people from rural South Africa. Methods We analysed data from the Health and Ageing in Africa: Longitudinal Studies of an INDEPTH Community (HAALSI) study, which enrolled participants aged 40 years and older nested within the Agincourt Health and Demographic Survey Site, South Africa. We created a 32-variable cumulative deficit frailty index using questionnaire (illnesses, symptoms and activities of daily living), physical performance and physiological indices, and blood test results. Each variable was dichotomised to 1 (deficit) or 0 (no deficit). The frailty index for each individual was calculated as the mean of all frailty variables. Frailty categories were defined using cut-offs from the UK electronic frailty index: 0-0.12 (non-frail), &gt;0.12-0.24 (mild frailty), &gt;0.24-0.36 (moderate frailty) and &gt;0.36 (severe frailty). Cox proportional hazards models, both unadjusted and adjusted for age and sex, were fitted to test the association between frailty status and all-cause mortality. Results We analysed data from 3989 participants, mean age 61 years (SD 13); 2175 (54.5%) were female. The mean follow-up period was 17 months; 1464 (36.7%) were non-frail, 2059 (51.6%) had mild frailty, 402 (10.1%) had moderate frailty and 64 (1.6%) had severe frailty. A total of 135 (3.4%) died. Adjusted Cox models showed worse frailty category was associated with higher risk of death compared with non-frail individuals: hazard ratios 1.94 (95% CI 1.23, 3.07) for mild frailty, 3.25 (95% CI 1.86, 5.68) for moderate frailty, and 5.50 (95% CI 2.44, 12.40) for severe frailty. Conclusions Frailty measured by a cumulative deficits index is common and predicts mortality in a rural population of older South Africans.

Burden of Potentially Harmful Medications and the Association With Quality of Life and Mortality Among Institutionalized Older People

2016 ◽  
Vol 17 (3) ◽  
pp. 276.e9-276.e14 ◽  
Author(s):  
Anna-Liisa Juola ◽  
Sarita Pylkkanen ◽  
Hannu Kautiainen ◽  
J. Simon Bell ◽  
Mikko P. Bjorkman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older People ◽  
Institutionalized Older People
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