Immediate physiological effects of listening to music before physical exercise in institutionalized older people with dementia

2021 ◽  
Vol 28 (3) ◽  
pp. 308-317
Author(s):  
Tamires Ferri Izzo ◽  
Maria Juana Beatriz Lima Candanedo ◽  
Aline Yumi Higuti ◽  
Lucas Magalhães Corrêa ◽  
Dayane Melo Campos ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Older People ◽  
Physiological Effects ◽  
Physiological Factors ◽  
Functional Changes ◽  
Positive Effects ◽  
The Third ◽  
Physical Exercises ◽  
People With Dementia ◽  
Institutionalized Older People

ABSTRACT The evolution of dementia is strongly related to cognitive, motor, and functional changes and to the presence of cardiovascular diseases. Disturbances vary according to phase of dementia and can limit instrumental and basic activities of daily living. The aim of this study was to analyze the immediate physiological effects of listening to music before physical exercise in institutionalized older people with moderate to advanced dementia. A randomized trial was conducted with 18 institutionalized older people with dementia (mean age was 79 years old, 52.6% were female), who were divided into a Training with Music Group (TWMG) and a Training without Music Group (TWtMG). The evaluation included heart rate (HR), blood pressure (BP) and HR variability (HRV). The assessment was conducted in a closed environment or in places with minimal visual and auditory stimulation. The TWMG was submitted to stimuli with music for 15 minutes and physical exercises for 30 minutes to improve/maintain their global mobility. The TWtMG performed the same physical exercises, however without music before physical exercise. The interventions lasted 12 weeks, and were performed individually once a week. In the TWMG, we observe a decrease in diastolic BP in the third session. In the sixth week, the HR increased after the session in both groups. TWMG improved HRV in the third session, with a difference between groups only after the session. After the sixth session, HRV values improved in both groups. In conclusion, listening to music before physical exercise is associated with positive effects in people with dementia, as it tends to maintain and improve physiological factors.

scholarly journals PHYSICAL EXERCISE AS STRATEGY FOR REDUCING BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS IN DEMENTIA (BPSD)

2021 ◽  
Author(s):  
Susana Rodrigues ◽  
Jamily Da Silva ◽  
Maria De Oliveira ◽  
Charleny De Santana ◽  
Kaliandra Carvalho ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Older People ◽  
Randomized Clinical Trials ◽  
Psychological Symptoms ◽  
Secondary Outcome ◽  
Control Group ◽  
Eligibility Criteria ◽  
Positive Effects ◽  
People With Dementia ◽  
Behavioral And Psychological Symptoms

Background: Older people with dementia may experience behavioral and psychological symptoms during the course of the illness. Non-pharmacological therapies are considered strategies to manage these symptoms. Objective: to investigate whether physical exercise reduces BPSD in older people with Mild Cognitive Impairment (MCI) and dementia. Methods: A systematic review was performed in the MEDLINE, SciELO, Web of Science, Scopus and SPORTDiscus databases from 2010 to 2020. Randomized clinical trials involving older people with MCI or dementia that evaluated BPSD as a primary or secondary outcome were included. The studies had an exercise-only group as an intervention compared to the control group. Results: Of the 175 publications identified, only 7 met the eligibility criteria; 4 studies showed positive effects in reducing BPSD, while the others did not differentiate the gains according to the type of protocol. Conclusion: Aerobic and muscle-strengthening exercises of moderate to vigorous intensity may have potential benefit in the management of BPSD, but studies vary in their conclusions. This review identified the need for further intervention studies to investigate the absolute effect of physical exercise and its impact on BPSD as a primary outcome, especially in the early stages of the disease.

Efficacy of physical exercise intervention on mobility and physical functioning in older people with dementia: A systematic review

2013 ◽  
Vol 48 (1) ◽  
pp. 85-93 ◽  
Author(s):  
Kaisu Pitkälä ◽  
Niina Savikko ◽  
Minna Poysti ◽  
Timo Strandberg ◽  
Marja-Liisa Laakkonen
Keyword(s):  
Systematic Review ◽  
Physical Exercise ◽  
Older People ◽  
Physical Functioning ◽  
Exercise Intervention ◽  
People With Dementia

scholarly journals Effects of Curcumin Supplementation on Inflammatory Markers, Muscle Damage, and Sports Performance during Acute Physical Exercise in Sedentary Individuals

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Kelly Aparecida Dias ◽  
Aline Rosignoli da Conceição ◽  
Lívya Alves Oliveira ◽  
Stephanie Michelin Santana Pereira ◽  
Stefany da Silva Paes ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Muscle Damage ◽  
Inflammatory Markers ◽  
Acute Exercise ◽  
Biological Activities ◽  
Muscle Performance ◽  
Sports Performance ◽  
Positive Effects ◽  
Physical Exercises ◽  
Acute Physical Exercise

Exhaustive and acute unusual physical exercise leads to muscle damage. Curcumin has been widely studied due to the variety of its biological activities, attributed to its antioxidant and anti-inflammatory properties. Furthermore, it has shown positive effects on physical exercise practitioners. However, there is no literature consensus on the beneficial effects of curcumin in acute physical activities performed by sedentary individuals. Therefore, we systematically reviewed evidence from clinical trials on the main effects of curcumin supplementation on inflammatory markers, sports performance, and muscle damage during acute physical exercises in these individuals. We searched PubMed/MEDLINE, Scopus, Web of Science, and Embase databases, and only original studies were analyzed according to the PRISMA guidelines. The included studies were limited to supplementation of curcumin during acute exercise. A total of 5 studies were selected. Methodological quality assessments were examined using the SYRCLE’s risk-of-bias tool. Most studies have shown positive effects of curcumin supplementation in sedentary individuals undergoing acute physical exercise. Overall, participants supplemented with curcumin showed less muscle damage, reduced inflammation, and better muscle performance. The studies showed heterogeneous data and exhibited methodological limitations; therefore, further research is necessary to ensure curcumin supplementation benefits during acute and high-intensity physical exercises. Additionally, mechanistic and highly controlled studies are required to improve the quality of the evidence and to elucidate other possible mechanisms. This study is registered with Prospero number CRD42021262718.

scholarly journals Dementia and road traffic accidents among non-institutionalized older people in Denmark: A Danish register-based nested case-control study

2018 ◽  
Vol 47 (2) ◽  
pp. 221-228 ◽  
Author(s):  
Jindong Ding Petersen ◽  
Volkert Dirk Siersma ◽  
René Depont Christensen ◽  
Maria Munch Storsveen ◽  
Connie Thurøe Nielsen ◽  
...  
Keyword(s):  
Older People ◽  
Traffic Accidents ◽  
Road Traffic ◽  
Conditional Logistic Regression ◽  
Geographic Location ◽  
Source Population ◽  
Older Individuals ◽  
Road Traffic Accidents ◽  
People With Dementia ◽  
Institutionalized Older People

Aim: We used register-based data to estimate the effect of all-type dementia on road traffic accidents (RTAs) risk, combined with comorbidities or sedative medicines, among non-institutionalized older people in Denmark. Methods: The source population was all residents in Denmark aged 65 years and older, alive as of January 1, 2008 ( n = 853,228). Cases were those who had any type of RTA in 2009–2014. Each case was matched for age, sex and geographic location to 4–6 controls. All-type dementia was ascertained using the International Classification of Diseases version 10 (ICD-10) diagnosis supplemented with prescribed medicine records. Eight chronic diseases were selected to assess comorbidities. Four types of medicines were categorized as sedative medicines for analysis. Conditional logistic regression with adjustment for education and marital status as well as either the number of comorbidities or sedative medications use was performed using STATA software. Results: Older people with dementia had lower RTAs risk compared to their controls (odds ratio = 0.43, 95% confidence interval (0.32–0.60), p < 0.001). Significant interaction was observed between dementia and the number of comorbidities for RTAs estimation. Conclusions: The significantly lower RTAs risk for older individuals with dementia observed in our study may be due to people with dementia living at home having a lower frequency of outdoor activities; that is, less exposure to traffic. However, this, together with the interaction between dementia and comorbidities as well as sedative medications, should be investigated further.

scholarly journals Beneficial Effects of Physical Activity on Subjects with Neurodegenerative Disease

2020 ◽  
Vol 5 (4) ◽  
pp. 94
Author(s):  
Laura Vizzi ◽  
Elvira Padua ◽  
Agata Grazia D’Amico ◽  
Virginia Tancredi ◽  
Giovanna D’Arcangelo ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Exercise ◽  
Neurodegenerative Diseases ◽  
Cognitive Skills ◽  
The Elderly ◽  
Elderly Subjects ◽  
Positive Effects ◽  
People With Dementia ◽  
Motor Practice ◽  
Psychomotor Functions

Studies on the effectiveness of physical exercise to treat and/or prevent mental disorders are essential and particularly appropriate, given the rapid growth of the elderly population and the consequent increase in the prevalence of neurodegenerative diseases. The onset of neurodegenerative diseases is subtle, and progression is irreversible, as there is still no cure capable of stopping them permanently. Therefore, we should not underestimate these diseases and should immediately begin to combine the treatment with physical activity adapted to specific needs. Indeed, it is well known that physical activity has positive effects on mobility, autonomy, and functional capacity, improving not only cognitive functions, but also reducing the risk of developing dementia. Despite several studies in this field, to date there are no specific and effective protocols that promote physical exercise in people with dementia. Based on this evidence, the aim of the present work was to verify whether an adapted physical exercise regimen could promote the maintenance of psychomotor functions in elderly subjects and, therefore, delay the irreversible effects of combinations of dementia and other pathologies associated with aging. Our results clearly show that exercise is very effective in improving psychomotor functions and delaying the progress of neurodegenerative diseases in humans, since we observed that the subjects maintained their cognitive skills after 8 months of physical activity, moreover, two patients presented an amelioration. Based on the results obtained, we recommend that the motor practice, in any chosen form, be considered an integral part of prevention programs based on an active lifestyle in older people. Future studies will be necessary to establish how long lasting the benefits of a specific physical activity are and whether they are enough to delay cognitive decline.

scholarly journals Physical Exercises By Giving Glutathione for Changes of Leukocytes, Neutrophils, and Lymphocytes Amounts

2020 ◽  
Vol 9 (2) ◽  
pp. 137-141
Author(s):  
Tuty Yanuarti ◽  
Sugiharto Sugiharto
Keyword(s):  
Physical Exercise ◽  
The Body ◽  
Control Group ◽  
Profile Measurement ◽  
Control Group Design ◽  
Group Design ◽  
The Third ◽  
Physical Exercises ◽  
Randomized Control ◽  
Age Range

Physical exercise changes the antibody endurance of each person. This study aims to determine in depth changes in the number of leukocytes, neutrophils, and lymphocytes using physical exercise after being given glutathione. The method used experimentally using a posttest randomized control group design. The study was conducted in three groups where each group consisting of men and women who are in the age range of 20-30 years. Each group consisted of 10 people (n), K1 was given a placebo, K2 was given glutathione 54 mg / kg BW, K3 given 108 mg / kg BW. All treatments are given intraperitoneally twice a day until the third day. Maximum physical exercise is swimming. On the third day after 3 hours of treatment (placebo or glutathione), then participants take a leukocyte profile measurement. The findings show that the number of leukocytes: K2> K1; P = 0.005; K2 - K3; P = 0.168; - K3; P 0.105, neutrophils: Kl, K2 and K3 are not different, even though K2 is highest, lymphocyte: K2> K1; P = 0.003, K1 - K3 and K2 - K3 is not different even though K2 is highest. The conclusion of this study is the number of leukocytes and lymphocytes treated with glutathione 54 mg / kg BW (K2) is significantly higher than K1 after strenuous physical exercise. Thus, the content of glutathione must be balanced with the body’s needs so that the body is healthy and is able to do the heavy activities.

scholarly journals Effects of Synergistic Massage and Physical Exercise on the Expression of Angiogenic Markers in Rat Tendons

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Waldemar Andrzejewski ◽  
Krzysztof Kassolik ◽  
Piotr Dziegiel ◽  
Bartosz Pula ◽  
Katarzyna Ratajczak-Wielgomas ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Mrna Level ◽  
Molecular Techniques ◽  
Control Group ◽  
Key Factors ◽  
Entire Study ◽  
The Third ◽  
Physical Exercises ◽  
Varied Duration ◽  
The Impact

Physical exercise and massage are regarded as key factors in regulating tendon structure. However, information on the mechanism through which massage influences the structure and biology of a tendon is scarce. In this study, we attempted to define the impact of these two activities on rat tendons by using morphological and molecular techniques, determining the expression of VEGF-A, FGF-2, and CD34 in the tendons of rats subjected to 10 weeks of physical exercise (running) with massage of varied duration. The group of rats that was trained and massaged during the entire study was characterized by the highest expression of these markers, compared to the rats subjected to massage before training and to the control group subjected to physical exercises only. The greatest significant differences, compared to the control, were noted in the expression of all the studied markers at mRNA level, and in the case of VEGF-A, at protein level, in the third and fifth weeks of the experiment. The results of this study could point to the synergistic impact of simultaneous massage and physical exercise on the expression of angiogenesis markers in rat tendons.

scholarly journals Physical Exercise During Pregnancy – How Active Are Pregnant Women in Germany and How Well Informed?

2017 ◽  
Vol 77 (05) ◽  
pp. 508-515 ◽  
Author(s):  
Thorsten Schmidt ◽  
Thorsten Heilmann ◽  
Luisa Savelsberg ◽  
Nicolai Maass ◽  
Burkhard Weisser ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Pregnant Women ◽  
First Trimester ◽  
University Hospital ◽  
Sufficient Evidence ◽  
Activity Levels ◽  
Positive Effects ◽  
The Third ◽  
Study Participants ◽  
Exercise During Pregnancy

Abstract Introduction There is sufficient evidence showing the positive effects of physical exercise on various aspects of pregnancy. This study evaluates knowledge and status of physical exercise among pregnant women. Methods The standardised paper-pencil questionnaire “Pregnancy Physical Activity Questionnaire” (PPAQ) as well as general demographic questions were used to assess the exercise behaviour of study participants. 83 questionnaires completed by women presenting to the Kiel University Hospital for antenatal assessment were included in the analysis. Results At the time of questionnaire completion 10 women were in the first trimester of pregnancy, 64 in the second, and 9 in the third. Just less than 90% of participants felt they had been informed “sufficiently” on the topic physical exercise during pregnancy, over 50% felt they were “well” or “very well” informed. Just less than half of participants received their information from a doctor (either their gynaecologist or general practitioner) and none of these felt “insufficiently” informed. Almost 80% of participants reported still doing no sport or less exercise than before falling pregnant. The maximum proportional energy expenditure for recreational activity – just under 20% – was in the third trimester. Women who felt they had been well counselled tended to have higher activity levels. Conclusion Study participants demonstrated a clear decline in physical exercise during pregnancy despite clear evidence of the benefits of regular exercise for pregnant women, and despite participants feeling they were well informed. Detailed information on the recommendations for physical exertion in pregnancy should form an integral part of antenatal counselling.

The effects of Cyclosporin-A (CYA) on the Ultrastructure of Gingival Mast Cells (GMC) in Behcet's disease (BD)

1990 ◽  
Vol 48 (3) ◽  
pp. 358-359
Author(s):  
Oktay Arda ◽  
Ulkü Noyan ◽  
Selgçk Yilmaz ◽  
Mustafa Taşyürekli ◽  
İsmail Seçkin ◽  
...  
Keyword(s):  
Unknown Etiology ◽  
Control Group ◽  
Target Cells ◽  
Gingival Hyperplasia ◽  
Cellular Activity ◽  
Direct Relation ◽  
Immune Disease ◽  
Genital Ulceration ◽  
Functional Changes ◽  
The Third

Turkish dermatologist, H. Beheet described the disease as recurrent triad of iritis, oral aphthous lesions and genital ulceration. Auto immune disease is the recent focus on the unknown etiology which is still being discussed. Among the other immunosupressive drugs, CyA included in it's treatment newly. One of the important side effects of this drug is gingival hyperplasia which has a direct relation with the presence of teeth and periodontal tissue. We are interested in the ultrastructure of immunocompetent target cells that were affected by CyA in BD.Three groups arranged in each having 5 patients with BD. Control group was the first and didn’t have CyA treatment. Patients who had CyA, but didn’t show gingival hyperplasia assembled the second group. The ones displaying gingival hyperplasia following CyA therapy formed the third group. GMC of control group and their granules are shown in FIG. 1,2,3. GMC of the second group presented initiation of supplementary cellular activity and possible maturing functional changes with the signs of increased number of mitochondria and accumulation of numerous dense cored granules next to few normal ones, FIG. 4,5,6.

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