Muscle actions on crossed and non-crossed joints during upright standing and gait: a comprehensive description based on induced acceleration analysis

2021 ◽  
pp. 110874
Author(s):  
Thales R. Souza ◽  
Wouter Schallig ◽  
Kirsten Veerkamp ◽  
Fabrício A. Magalhães ◽  
Liria Okai-Nóbrega ◽  
...  
Keyword(s):  
Comprehensive Description ◽  
Upright Standing ◽  
Acceleration Analysis ◽  
Muscle Actions

Influence of increased nutrient supply on Microcystis aeruginosa at cellular and proteomic levels

2020 ◽  
Vol 85 ◽  
pp. 47-58
Author(s):  
Y Jiang ◽  
Y Liu
Keyword(s):  
Microcystis Aeruginosa ◽  
Regulatory Protein ◽  
Acid Synthesis ◽  
Nutrient Supply ◽  
Nitrogen Supply ◽  
Nitrogen And Phosphorus ◽  
Comprehensive Description ◽  
Amino Acid Synthesis ◽  
High Nutrient ◽  
Proteomic Responses

Various studies have observed that increased nutrient supply promotes the growth of bloom-forming cyanobacteria, but only a limited number of studies have investigated the influence of increased nutrient supply on bloom-forming cyanobacteria at the proteomic level. We investigated the cellular and proteomic responses of Microcystis aeruginosa to elevated nitrogen and phosphorus supply. Increased supply of both nutrients significantly promoted the growth of M. aeruginosa and the synthesis of chlorophyll a, protein, and microcystins. The release of microcystins and the synthesis of polysaccharides negatively correlated with the growth of M. aeruginosa under high nutrient levels. Overexpressed proteins related to photosynthesis, and amino acid synthesis, were responsible for the stimulatory effects of increased nutrient supply in M. aeruginosa. Increased nitrogen supply directly promoted cyanobacterial growth by inducing the overexpression of the cell division regulatory protein FtsZ. NtcA, that regulates gene transcription related to both nitrogen assimilation and microcystin synthesis, was overexpressed under the high nitrogen condition, which consequently induced overexpression of 2 microcystin synthetases (McyC and McyF) and promoted microcystin synthesis. Elevated nitrogen supply induced the overexpression of proteins involved in gas vesicle organization (GvpC and GvpW), which may increase the buoyancy of M. aeruginosa. Increased phosphorus level indirectly affected growth and the synthesis of cellular substances in M. aeruginosa through the mediation of differentially expressed proteins related to carbon and phosphorus metabolism. This study provides a comprehensive description of changes in the proteome of M. aeruginosa in response to an increased supply of 2 key nutrients.

Cognitive dominants of the conceptual sphere in the novel “of human bondage” by W. S. Maugham

2020 ◽  
Vol 6 (1) ◽  
pp. 48-61
Author(s):  
Olga B. Ponomareva ◽  
Valeriya I. Orlova
Keyword(s):  
Cognitive Linguistics ◽  
Meaning Of Life ◽  
The Novel ◽  
Thought Processes ◽  
New Paradigm ◽  
Comprehensive Description ◽  
Semantic Fields ◽  
Linguistic Representations ◽  
Basic Concepts ◽  
Linguistic Methods

This article presents a comprehensive analysis of the basic concepts that make up the conceptual sphere of the novel “Of Human Bondage” by W. S. Maugham. These concepts act as cognitive dominants of the linguistic consciousness of the protagonist’s linguistic personality in the work under study. The novelty of this research lies in the fact that it is performed within the framework of a new paradigm of linguistics — the cognitive linguistics, which involves the study of mental and linguistic representations of thought processes that occur during the perception of information. Moreover, the novel “Of Human Bondage” by W. S. Maugham has not attracted the attention of linguists-cognitologists previously, which adds to the novelty of this article. In addition, the present study provides a comprehensive description of the basic concepts making up the conceptual sphere of the novel. The linguistic methods of representing various concepts in the analyzed work are determined by the national, personal, cultural, and psychological aspects of Maugham’s thinking. The authors employ a communicative-cognitive methodological analysis proposed by N. S. Bolotnova involving the modeling of textual and intertextual semantic fields of artistic concepts and the analysis of the conceptual sphere of a literary text. The universal concepts RELIGION, LOVE, PASSION, THE MEANING OF LIFE, which constitute the conceptual sphere of the novel by W. S. Maugham “Of Human Bondage”, are analyzed. The main result of the study is that THE MEANING OF LIFE concept is universal, not individual, and it includes other universal concepts, such as RELIGION, LOVE, PASSION, THE MEANING OF LIFE, conceptual metaphors and metonyms, symbols, and other words-associates, which constitute the broad figurative and evaluative periphery of the conceptual sphere of the novel.

Centrality Measures

2018 ◽  
Author(s):  
Ginestra Bianconi
Keyword(s):  
State Of The Art ◽  
Centrality Measures ◽  
Eigenvector Centrality ◽  
Multilayer Networks ◽  
Comprehensive Description ◽  
Multilayer Network ◽  
Suitable Definition ◽  
Katz Centrality ◽  
Pagerank Centrality

Defining the centrality of nodes and layers in multilayer networks is of fundamental importance for a variety of applications from sociology to biology and finance. This chapter presents the state-of-the-art centrality measures able to characterize the centrality of nodes, the influences of layers or the centrality of replica nodes in multilayer and multiplex networks. These centrality measures include modifications of the eigenvector centrality, Katz centrality, PageRank centrality and Communicability to the multilayer network scenario. The chapter provides a comprehensive description of the research of the field and discusses the main advantages and limitations of the different definitions, allowing the readers that wish to apply these techniques to choose the most suitable definition for his or her case study.

A comprehensive description of functioning and disability in children with velopharyngeal insufficiency

2013 ◽  
Vol 46 (4) ◽  
pp. 388-400 ◽  
Author(s):  
Agnieszka Dzioba ◽  
Elizabeth Skarakis-Doyle ◽  
Philip C. Doyle ◽  
Wenonah Campbell ◽  
Allyson D. Dykstra
Keyword(s):  
Velopharyngeal Insufficiency ◽  
Comprehensive Description

scholarly journals Multifunctional Role of Astrocyte Elevated Gene-1 (AEG-1) in Cancer: Focus on Drug Resistance

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1792
Author(s):  
Debashri Manna ◽  
Devanand Sarkar
Keyword(s):  
Drug Resistance ◽  
Cancer Cells ◽  
Cancer Development ◽  
Epigenetic Alterations ◽  
Hallmarks Of Cancer ◽  
Comprehensive Description ◽  
Molecular Abnormalities ◽  
Selective Pressures ◽  
Resistance To Chemotherapy

Cancer development results from the acquisition of numerous genetic and epigenetic alterations in cancer cells themselves, as well as continuous changes in their microenvironment. The plasticity of cancer cells allows them to continuously adapt to selective pressures brought forth by exogenous environmental stresses, the internal milieu of the tumor and cancer treatment itself. Resistance to treatment, either inherent or acquired after the commencement of treatment, is a major obstacle an oncologist confronts in an endeavor to efficiently manage the disease. Resistance to chemotherapy, chemoresistance, is an important hallmark of aggressive cancers, and driver oncogene-induced signaling pathways and molecular abnormalities create the platform for chemoresistance. The oncogene Astrocyte elevated gene-1/Metadherin (AEG-1/MTDH) is overexpressed in a diverse array of cancers, and its overexpression promotes all the hallmarks of cancer, such as proliferation, invasion, metastasis, angiogenesis and chemoresistance. The present review provides a comprehensive description of the molecular mechanism by which AEG-1 promotes tumorigenesis, with a special emphasis on its ability to regulate chemoresistance.

scholarly journals Information Quality Assessment for Data Fusion Systems

Data ◽  
2021 ◽  
Vol 6 (6) ◽  
pp. 60
Author(s):  
Miguel A. Becerra ◽  
Catalina Tobón ◽  
Andrés Eduardo Castro-Ospina ◽  
Diego H. Peluffo-Ordóñez
Keyword(s):  
Data Fusion ◽  
Information Quality ◽  
Engineering Process ◽  
Comprehensive Description ◽  
Research Issues ◽  
Fusion Systems ◽  
General Data ◽  
Fusion Engineering ◽  
And Performance ◽  
Key Aspects

This paper provides a comprehensive description of the current literature on data fusion, with an emphasis on Information Quality (IQ) and performance evaluation. This literature review highlights recent studies that reveal existing gaps, the need to find a synergy between data fusion and IQ, several research issues, and the challenges and pitfalls in this field. First, the main models, frameworks, architectures, algorithms, solutions, problems, and requirements are analyzed. Second, a general data fusion engineering process is presented to show how complex it is to design a framework for a specific application. Third, an IQ approach, as well as the different methodologies and frameworks used to assess IQ in information systems are addressed; in addition, data fusion systems are presented along with their related criteria. Furthermore, information on the context in data fusion systems and its IQ assessment are discussed. Subsequently, the issue of data fusion systems’ performance is reviewed. Finally, some key aspects and concluding remarks are outlined, and some future lines of work are gathered.

scholarly journals Coverage Layout Design Rules and Insertion Utilities for CMP-Related Processes

2020 ◽  
Vol 11 (1) ◽  
pp. 2
Author(s):  
Eitan N. Shauly ◽  
Sagee Rosenthal
Keyword(s):  
Integrated Circuit ◽  
Thermal Effects ◽  
Process Integration ◽  
Proximity Effects ◽  
Published Data ◽  
Metal Gate ◽  
Comprehensive Description ◽  
Advanced Technologies ◽  
High K ◽  
Rf Devices

The continuous scaling needed for higher density and better performance has introduced some new challenges to the planarity processes. This has resulted in new definitions of the layout coverage rules developed by the foundry and provided to the designers. In advanced technologies, the set of rules considers both the global and the local coverage of the front-end-of line (FEOL) dielectric layers, to the back-end-of-line (BEOL) Cu layers and Al layers, to support high-k/Metal Gate process integration. For advance technologies, a new set of rules for dummy feature insertion was developed by the integrated circuit (IC) manufacturers in order to fulfill coverage limits. New models and utilities for fill insertion were developed, taking into consideration the design coverage, thermal effects, sensitive signal line, critical analog and RF devices like inductors, and double patterning requirements, among others. To minimize proximity effects, cell insertion was also introduced. This review is based on published data from leading IC manufacturers with a careful integration of new experimental data accumulated by the authors. We aim to present a typical foundry perspective. The review provides a detailed description of the chemical mechanical polishing (CMP) process and the coverage dependency, followed by a comprehensive description of coverage rules needed for dielectric, poly, and Cu layers used in advanced technologies. Coverage rules verification data are then presented. RF-related aspects of some rules, like the size and the distance of dummy features from inductors, are discussed with additional design-for-manufacturing layout recommendations as developed by the industry.

scholarly journals Anisotropy in ω Centauri and 47 Tucanae

1988 ◽  
Vol 126 ◽  
pp. 663-664
Author(s):  
G. Meylan
Keyword(s):  
Globular Clusters ◽  
Velocity Dispersion ◽  
Dynamical Models ◽  
Comprehensive Description ◽  
Great Opportunity ◽  
The Galaxy

The southern sky gives us the great opportunity to observe two among the brightest and nearest globular clusters of the Galaxy: ω Cen and 47 Tuc. For these giant clusters, we present the comparison between observations and King-Michie multi-mass dynamical models with anisotropy in the velocity dispersion. A more comprehensive description of this work is to be published (Meylan 1986a,b).

Sign in / Sign up

Export Citation Format

Share Document