Real-time monitoring and automatic density control of large-scale microalgal cultures using near infrared (NIR) optical density sensors

2006 ◽  
Vol 122 (2) ◽  
pp. 209-215 ◽  
Author(s):  
J.M. Sandnes ◽  
T. Ringstad ◽  
D. Wenner ◽  
P.H. Heyerdahl ◽  
T. Källqvist ◽  
...  
2014 ◽  
Vol 189 ◽  
pp. 120-128 ◽  
Author(s):  
José Alves-Rausch ◽  
Roland Bienert ◽  
Christian Grimm ◽  
Dirk Bergmaier

2015 ◽  
Vol 51 (32) ◽  
pp. 6948-6951 ◽  
Author(s):  
Yanfeng Zhang ◽  
Qian Yin ◽  
Jonathan Yen ◽  
Joanne Li ◽  
Hanze Ying ◽  
...  

Anin vitroandin vivodrug-reporting system is developed for real-time monitoring of drug release via the analysis of the concurrently released near-infrared fluorescence dye.


2017 ◽  
Vol 985 ◽  
pp. 41-53 ◽  
Author(s):  
Rodrigo R. de Oliveira ◽  
Ricardo H.P. Pedroza ◽  
A.O. Sousa ◽  
Kássio M.G. Lima ◽  
Anna de Juan

2019 ◽  
Vol 162 ◽  
pp. 802-807 ◽  
Author(s):  
Qiang Li ◽  
Chenxu Yan ◽  
Jie Zhang ◽  
Zhiqian Guo ◽  
Wei-Hong Zhu

2021 ◽  
Author(s):  
Biswajit Roy ◽  
Rakesh Mengji ◽  
Samrat Roy ◽  
Bipul Pal ◽  
Avijit Jana ◽  
...  

In recent times, organelle-targeted drug delivery systems gained tremendous attention due to the site specific delivery of active drug molecules resulting in enhanced bioefficacy. In this context, the phototriggered drug delivery system (DDS) for releasing an active molecule is superior as it provides spatial and temporal control over the release. So far, near infrared (NIR) light responsive organelle targeted DDS has not yet been developed. Hence, we introduced a two-photon NIR-light responsive lysosome targeted ʽAIE + ESIPTʼ active single component DDS based on naphthalene chromophore. The Two-photon absorption cross-section of our DDS is 142 GM at 850 nm. The DDS was converted into pure organic nanoparticles for biological applications. Our nano-DDS is capable of selective targeting, AIE-luminogenic imaging, and drug release within the lysosome. In vitro studies using cancerous cell lines showed that our single component photoresponsive nanocarrier exhibited enhanced cytotoxicity and real-time monitoring ability of the drug release.


BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e038282
Author(s):  
Hafizah Jusril ◽  
Iwan Ariawan ◽  
Rita Damayanti ◽  
Lutfan Lazuardi ◽  
Miriam Musa ◽  
...  

ObjectiveTo assess the contribution of a digital health real-time monitoring platform towards the achievement of coverage targets during a national immunisation campaign in Indonesia.InterventionsA digital health platform was introduced to facilitate real-time reporting and data visualisation. Health workers submitted reports of children immunised each day by geolocation using mobile phones. Automated reports were generated for programme managers at all levels to enable early responses to coverage gaps.MethodsRisk profiles were generated for each district to assess precampaign immunisation programme performance. Digital health platform use and progress towards targets were monitored continuously throughout the campaign. Study outcomes were total coverage and time to achieve full (100%) coverage. Kaplan-Meier, Cox and linear regression analyses were used to estimate the associations and outcomes after adjusting for district risk profiles. A complementary qualitative assessment explored user experiences and acceptance through interviews with vaccinators and programme managers in provinces and districts selected through multistage random sampling.ResultsBetween August and December 2018, 6462 health facilities registered to use the digital health platform across 28 provinces and 395 districts. After adjusting for precampaign district risk profile and intracampaign delays due to vaccine hesitancy, districts with greater platform utilisation demonstrated higher coverage overall (R2=0.28, p<0.0001) and a shorter interval to achieving full coverage (>75% reporting compliance; Risk Ratio 15.4, 95% CI 5.8 to 40.6). Stronger effects were observed among districts experiencing implementation delays due to vaccine hesitancy. Results from 106 key informant interviews conducted in 6 provinces and 18 districts suggest high degrees of acceptability, ease of use and satisfaction.ConclusionA digital health platform introduced for real-time monitoring of a national immunisation campaign in Indonesia was feasible, well liked and associated with improved problem solving and programme performance, particularly among districts affected by vaccine hesitancy.Trial registration numberISRCTN10850448.


2016 ◽  
Vol 512 (1) ◽  
pp. 61-74 ◽  
Author(s):  
Andrés D. Román-Ospino ◽  
Ravendra Singh ◽  
Marianthi Ierapetritou ◽  
Rohit Ramachandran ◽  
Rafael Méndez ◽  
...  

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