Simultaneous separation of acid and basic bioactive peptides by electrodialysis with ultrafiltration membrane

2006 ◽  
Vol 123 (3) ◽  
pp. 314-328 ◽  
Author(s):  
Jean-François Poulin ◽  
Jean Amiot ◽  
Laurent Bazinet
Desalination ◽  
2006 ◽  
Vol 200 (1-3) ◽  
pp. 620 ◽  
Author(s):  
Jean-François Poulin ◽  
Monica Araya-Farias ◽  
Jean Amiot ◽  
Laurent Bazinet

Membranes ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 90 ◽  
Author(s):  
Rémi Przybylski ◽  
Laurent Bazinet ◽  
Loubna Firdaous ◽  
Mostafa Kouach ◽  
Jean-François Goossens ◽  
...  

The fractionation of bioactive peptides from hydrolysate is a main challenge to produce efficient alternative for synthetic additives. In this work, electrodialysis with ultrafiltration membrane (EDUF) was proposed to increase the purity of one antimicrobial peptide from slaughterhouse by-product hydrolysate. This targeted-peptide, α137–141 (653 Da, TSKYR), inhibits a large spectrum of microbial growths and delays meat rancidity; therefore, if concentrated, it could be used as food antimicrobial. In this context, three pH values were investigated during EDUF treatment to increase the α137–141 purity: 4.7, 6.5, and 9. pH 9 showed the highest purity increase—75-fold compared to the initial hydrolysate. Although the whole hydrolysate contains more than 100 peptides, only six peptides were recovered at a significant concentration. In this fraction, the α137–141 peptide represented more than 50% of the recovered total peptide concentration. The EDUF α137–141-enriched fraction obtained in this optimized condition would be a promising natural preservative to substitute synthetic additives used to protect food.


2019 ◽  
Vol 579 ◽  
pp. 190-198 ◽  
Author(s):  
Xiaofeng Fang ◽  
Jiansheng Li ◽  
Bangxing Ren ◽  
Ying Huang ◽  
Dapeng Wang ◽  
...  

2015 ◽  
Vol 30 (2) ◽  
pp. 171 ◽  
Author(s):  
CHEN Tao-Tao ◽  
LI Dan ◽  
JING Wen-Heng ◽  
FAN Yi-Qun ◽  
XING Wei-Hong

2018 ◽  
Vol 42 ◽  
pp. 256-265
Author(s):  
Konstantin V. Simonov ◽  
Stanislav P. Mitrakhovich

The article examines the possibility of transfer to bipartisan system in Russia. The authors assess the benefits of the two-party system that include first of all the ensuring of actual political competition and authority alternativeness with simultaneous separation of minute non-system forces that may contribute to the country destabilization. The authors analyze the accompanying risks and show that the concept of the two-party system as the catalyst of elite schism is mostly exaggerated. The authors pay separate attention to the experience of bipartisan system implementation in other countries, including the United States. They offer detailed analysis of the generated concept of the bipartisanship crisis and show that this point of view doesn’t quite agree with the current political practice. The authors also examine the foreign experience of the single-party system. They show that the success of the said system is mostly insubstantial, besides many of such systems have altered into more complex structures, while commentators very often use not the actual information but the established myths about this or that country. The authors also offer practical advice regarding the potential technologies of transition to the bipartisan system in Russia.


1996 ◽  
Vol 34 (9) ◽  
pp. 157-164 ◽  
Author(s):  
Kim C.-H. ◽  
M. Hosomi ◽  
A. Murakami ◽  
M. Okada

Effects of clay on fouling due to organic substances and clay were evaluated by model fouling materials and kaolin. Model fouling materials selected were protein, polysaccharide, fulvic acid, humic acid and algogenic matter (EOM:ectracellular organic matter, microbial decomposition products) and kaolin was selected as the clay material. Polysulfone membrane (MWCO(Molecular Weight Cut-Off) 10,000, 50,000 and 200,000) was used as an ultrafiltration membrane. In particular, the flux measurement of solutions containing algogenic matter used an ultrafiltration membrane of MWCO 50,000. The flux of protein and polysaccharide with coexistence of kaolin increased in the case of the ratio of MW/MWCO being greater than one, but did not increase in the case of the MW/MWCO ratio being below one. In contrast, the flux of fulvic acid and humic acid with coextence of kaolin decreased regardless of the ratio of MW/MWCO. The addition of dispersion agent and coagulant in the organic substances and kaolin mixture solution changed the size distribution of kaolin, and resulted in a change of the flux. EOM and microbial decomposition products decreased with the increase of the fraction of organic matter having molecular weight more than MWCO of membrane. The flux of the algogenic organic matter with coexistence of kaolin decreased with the increase of the amount of kaolin. It was suggested that the decline of the flux with coexistence of kaolin was due to the change of the resistance of the kaolin cake layer corresponding to the change in kaolin size distribution with charge.


1998 ◽  
Vol 38 (4-5) ◽  
pp. 513-520 ◽  
Author(s):  
O. Mizuno ◽  
H. Takagi ◽  
T. Noike

The biological sulfate removal in the acidogenic bioreactor with an ultrafiltration membrane system was investigated at 35°C. Sucrose was used as the sole organic substrate. The sulfate concentration in the substrate ranged from 0 to 600mgS·1−1. The chemostat reactor was operated to compare with the membrane bioreactor. The fouling phenomenon caused by FeS precipitate was observed at higher concentration of sulfate. However, it was possible to continuously operate the membrane bioreactor by cleaning the membrane. The efficiency of sulfate removal by sulfate reduction reached about 100% in the membrane bioreactor, and 55 to 87% of sulfide was removed from the permeate by the membrane filtration. The composition of the metabolite was remarkably changed by the change in sulfate concentration. When the sulfate concentration increased, acetate and 2-proponol significantly increased while n-butyrate and 3-pentanol decreased. The sulfate-reducing bacteria play the role as acetogenic bacteria consuming volatile fatty acids and alcohols as electron donors under sulfate-rich conditions. The results show that the acidogenesis and sulfate reduction simultaneously proceed in the membrane bioreactor.


2016 ◽  
Vol 23 (12) ◽  
pp. 1052-1060 ◽  
Author(s):  
Bert Gevaert ◽  
Lieselotte Veryser ◽  
Frederick Verbeke ◽  
Evelien Wynendaele ◽  
Bart Spiegeleer

2019 ◽  
Vol 26 (9) ◽  
pp. 664-675
Author(s):  
Sulochana Priya

Bioactive peptides are short chain of amino acids (usually 2-20) that are linked by amide bond in a specific sequence which have some biological effects in animals or humans. These can be of diverse origin like plant, animal, fish, microbe, marine organism or even synthetic. They are successfully used in the management of many diseases. In recent years increased attention has been raised for its effects and mechanism of action in various disease conditions like cancer, immunity, cardiovascular disease, hypertension, inflammation, diabetes, microbial infections etc. Bioactive peptides are more bioavailable and less allergenic when compared to total proteins. Food derived bioactive peptides have health benefits and its demand has increased tremendously over the past decade. This review gives a view on last two years research on potential bioactive peptides derived from food which have significant therapeutic effects.


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