scholarly journals The 1-min sit-to-stand test in cystic fibrosis — Insights into cardiorespiratory responses

2017 ◽  
Vol 16 (6) ◽  
pp. 744-751 ◽  
Author(s):  
Thomas Radtke ◽  
Helge Hebestreit ◽  
Milo A. Puhan ◽  
Susi Kriemler
PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246781
Author(s):  
Yann Combret ◽  
Fairuz Boujibar ◽  
Charlotte Gennari ◽  
Clément Medrinal ◽  
Sophie Sicinski ◽  
...  

Background Functional exercise capacity assessment is recommended in children with cystic fibrosis (CF). The six-minute walk test (6MWT) is a valid evaluation of exercise capacity but can be technically complex. Inversely, the sit-to-stand test (STST) is a simple method to evaluate exercise capacity, and is validated in healthy children and adults with CF. This study aimed to evaluate STST measurement properties in children and adolescents with CF. Methods In this multicenter study, children with CF (6 to 18 years) performed two iterations of both the STST and the 6MWT in a randomized order. Criterion validity was determined by assessing correlations between STST repetitions and 6MWT distance (6MWD). Intra-rater reliability, test-retest repeatability, mean bias and limits of agreement were also assessed. Relationships with other outcomes (i.e. respiratory and quadriceps muscle strength) and cardio-respiratory responses were analysed for both tests. Results Thirty-six children with CF were included (mean age 12.0 ±3.5 years and FEV1 95.8 ±25.0%). On average, 39.6 ±10.5 repetitions were performed during the STST and mean 6MWD was 596.0 ±102.6 meters. STST number of repetitions was significantly correlated with 6MWD (r = 0.48; p<0.01). Both tests had very good intra-rater reliability (ICCSTST = 0.91 (95%CI 0.76–0.96) and ICC6MWT = 0.94 (95%CI 0.85–0.97)), and a significant test-retest learning effect. The number of STST repetitions was not correlated with quadriceps or respiratory muscle strength test, and the STST induced fewer cardio-respiratory responses than the 6MWT. Conclusions The STST is an easy-to-use functional test with moderate criterion validity when compared to the 6MWT in children with CF, probably because both tests measure different components of functional exercise capacity. The STST is useful when the 6MWT is unfeasible, however further investigations are required to explore the clinical implications of STST results in children with CF. Clinical trial registration NCT03069625.


Pulmonology ◽  
2021 ◽  
Author(s):  
Yann Combret ◽  
Guillaume Prieur ◽  
Fairuz Boujibar ◽  
Francis-Edouard Gravier ◽  
Pauline Smondack ◽  
...  

2021 ◽  
Author(s):  
Sophie Hardy ◽  
Silvia Berardis ◽  
Anne-Sophie Aubriot ◽  
Gregory Reychler ◽  
Sophie Gohy

Abstract Background: Quadriceps muscle weakness and reduced exercise tolerance are prevalent in patients with cystic fibrosis (CF) and associated with a worse prognosis. The one-minute sit-to-stand test (1STST) has been proposed to evaluate exercise capacity and assess quadriceps strength. The aim of the study was to correlate the 1STST and the maximal isometric voluntary contraction of the quadriceps (MVCQ) evaluated by the dynamometer in stable patients with CF and to evaluate the impact of intravenous (IV) antibiotherapy.Methods: MVCQ and exercise capacity (dynamometer and 1STST) were measured in stable patients with CF at a routine visit, at the admission and the discharge of an IV antibiotherapy. Patients wore an activity monitor during 72h during IV treatment. Results: 51 stable patients with CF at a routine visit and 30 treated with IV antibiotherapy were recruited. In stable patients, the number of repetitions was reduced to 2101nxkg±657 (mean±SD), representing 79% of the predicted values (%PV) (7;142) (median (min;max)) as well as the MVCQ to 78.64N-m (23.21;170.34), representing 57%PV±26. The 1STST was correlated to MVCQ (r=0.536;p<0.0001) and lung function (r=0.508;p=0.0001). Over the IV antibiotherapy course, the 1STST improves significantly like lung function and body mass index while a positive trend for MVCQ was observed. The gain of 1STST was correlated to the change in MVCQ (r=0.441;p=0.015) and was significantly higher in hospitalized patients versus home therapy.Conclusions: The 1STST is a good alternative to the dynamometer to evaluate and assess muscular weakness for the routine visit and IV antibiotherapy.


2016 ◽  
Vol 15 (2) ◽  
pp. 223-226 ◽  
Author(s):  
Thomas Radtke ◽  
Milo A. Puhan ◽  
Helge Hebestreit ◽  
Susi Kriemler

Author(s):  
Giulia Foccardi ◽  
Marco Vecchiato ◽  
Daniel Neunhaeuserer ◽  
Michele Mezzaro ◽  
Giulia Quinto ◽  
...  

Although the efficacy of cardiac rehabilitation (CR) is proven, the need to improve patients’ adherence has emerged. There are only a few studies that have investigated the effect of sending text messages after a CR period to stimulate subjects’ ongoing engagement in regular physical activity (PA). A randomized controlled pilot trial was conducted after CR, sending a daily PA text message reminder to an intervention group (IG), which was compared with a usual care control group (CG) during three months of follow-up. Thirty-two subjects were assessed pre- and post-study intervention with GPAQ, submaximal iso-watt exercise testing, a 30 s sit-to-stand test, a bilateral arm curl test, and a final survey on a seven-point Likert scale. A statistically significant difference in the increase of moderate PA time (Δ 244.7 (95% CI 189.1, 300.4) minutes, p < 0.001) and in the reduction of sedentary behavior time (Δ −77.5 (95% CI 104.9, −50.1) minutes, p = 0.004) was shown when the IG was compared with the CG. This was associated with an improvement in heart rate, blood pressure, and patients’ Borg rating on the category ratio scale 10 (CR10) in iso-watt exercise testing (all p < 0.05). Furthermore, only the IG did not show a worsening of the strength parameters in the follow-up leading to a change of the 30 s sit-to-stand test with a difference of +2.2 (95% CI 1.23, 3.17) repetitions compared to CG (p = 0.03). The telemedical intervention has been appreciated by the IG, whose willingness to continue with regular PA emerged to be superior compared to the CG. Text messages are an effective and inexpensive adjuvant after phase 2 CR that improves adherence to regular PA. Further studies are needed to confirm these results in a larger patient population and in the long term.


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