A survey of place-exchange reaction for the preparation of water-soluble gold nanoparticles

Citrate gold nanoparticles of 13.5 nm average diameters have been synthesized by Turkevich method and further functionalized by place exchange reaction using mercaptosuccinic acid (MSA), 1,4-benezenedimethanethiol (1,4BDMT) or mercaptoundecanoic acid (MUA) as the incoming ligands. In the first case, the functionalization of the gold clusters with MSA yielded solution of blue color and large aggregates on carbon grids. Moreover, after filtration and drying, any film formed by hydrogen bonding, could not be removed from the filter, being embedded into the filter texture. The second ligand used for the place exchange reaction, the 1,4BDMT, determined the change of the solution color from red to dark purple, and generation of a purple powder but no film formation. In the third case, the purification and drying of the MUA functionalized gold clusters yielded films of purple color with homogenous composition, robustness, soft topographies and remarkable optical properties which were dependent on their thicknesses. The Au-MUA NP films obtained are new, being generated by hydrogen bonding and having features which makes them very attractive for the fabrication of optoelectronic devices. The long alkyl chained thiol proved to be the adequate ligand for film synthesis.

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Molecularly Imprinted Sensor for Ascorbic Acid Based on Gold Nanoparticles and Multiwalled Carbon Nanotubes

Current Analytical Chemistry ◽

10.2174/1573411015666191029152332 ◽

2020 ◽

Vol 16 (7) ◽

pp. 905-913

Author(s):

Youyuan Peng ◽

Qingshan Miao

Keyword(s):

Carbon Nanotubes ◽

Gold Nanoparticles ◽

Ascorbic Acid ◽

Multiwalled Carbon Nanotubes ◽

Ph Value ◽

Biological Fluids ◽

Water Soluble ◽

Multiwalled Carbon ◽

Experimental Conditions ◽

Molecularly Imprinted

Background: L-Ascorbic acid (AA) is a kind of water soluble vitamin, which is mainly present in fruits, vegetables and biological fluids. As a low cost antioxidant and effective scavenger of free radicals, AA may help to prevent diseases such as cancer and Parkinson’s disease. Owing to its role in the biological metabolism, AA has also been utilized for the therapy of mental illness, common cold and for improving the immunity. Therefore, it is very necessary and urgent to develop a simple, rapid and selective strategy for the detection of AA in various samples. Methods: The molecularly imprinted poly(o-phenylenediamine) (PoPD) film was prepared for the analysis of L-ascorbic acid (AA) on gold nanoparticles (AuNPs) - multiwalled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE) by electropolymerization of o-phenylenediamine (oPD) and AA. Experimental parameters including pH value of running buffer and scan rates were optimized. Scanning electron microscope (SEM), fourier-transform infrared (FTIR) spectra, cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were utilized for the characterization of the imprinted polymer film. Results: Under the selected experimental conditions, the DPV peak currents of AA exhibit two distinct linear responses ranging from 0.01 to 2 μmol L-1 and 2 to 100 μmol L-1 towards the concentrations of AA, and the detection limit was 2 nmol L-1 (S/N=3). Conclusion: The proposed electrochemical sensor possesses excellent selectivity for AA, along with good reproducibility and stability. The results obtained from the analysis of AA in real samples demonstrated the applicability of the proposed sensor to practical analysis.

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Gold nanoparticles generated and stabilized by water soluble curcumin–polymer conjugate: Blood compatibility evaluation and targeted drug delivery onto cancer cells

Journal of Colloid and Interface Science ◽

10.1016/j.jcis.2011.11.024 ◽

2012 ◽

Vol 368 (1) ◽

pp. 144-151 ◽

Cited By ~ 112

Author(s):

S. Manju ◽

K. Sreenivasan

Keyword(s):

Drug Delivery ◽

Gold Nanoparticles ◽

Cancer Cells ◽

Targeted Drug Delivery ◽

Blood Compatibility ◽

Water Soluble ◽

Polymer Conjugate ◽

Targeted Drug

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Synthesis and Characterization of Water-Soluble Monolayer-Protected Gold Nanoparticles

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.415-417.617 ◽

2011 ◽

Vol 415-417 ◽

pp. 617-620 ◽

Cited By ~ 1

Author(s):

Yan Su ◽

Ying Yun Lin ◽

Yu Li Fu ◽

Fan Qian ◽

Xiu Pei Yang ◽

...

Keyword(s):

Electron Microscopy ◽

Transmission Electron Microscopy ◽

Particle Size ◽

Gold Nanoparticles ◽

Average Particle Size ◽

Water Soluble ◽

Synthesis And Characterization ◽

Average Particle ◽

Transmission Electron

Water-soluble gold nanoparticles (AuNPs) were prepared using 2-mercapto-4-methyl-5- thiazoleacetic acid (MMTA) as a stabilizing agent and sodium borohydride (NaBH4) as a reducing agent. The AuNPs product was analyzed by transmission electron microscopy (TEM), UV-vis absorption spectroscopy and Fourier transform infrared spectroscopy (FTIR). The TEM image shows that the particles were well-dispersed and their average particle size is about 5 nm. The UV-vis absorption and FTIR spectra confirm that the MMTA-AuNPs was stabilized by the carboxylate ions present on the surface of the AuNPs.

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Water-soluble low-molecular-weight cellulose chains radially oriented on gold nanoparticles

Cellulose ◽

10.1007/s10570-011-9535-x ◽

2011 ◽

Vol 18 (4) ◽

pp. 929-936 ◽

Cited By ~ 6

Author(s):

Yukiko Enomoto-Rogers ◽

Hiroshi Kamitakahara ◽

Arata Yoshinaga ◽

Toshiyuki Takano

Keyword(s):

Molecular Weight ◽

Gold Nanoparticles ◽

Water Soluble ◽

Low Molecular Weight

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Luminescent, water-soluble gold nanoparticles functionalised with 3MLCT emitting rhenium complexes

Chemical Communications ◽

10.1039/b905692k ◽

2009 ◽

pp. 4278 ◽

Cited By ~ 21

Author(s):

Andrew J. Hallett ◽

Paul Christian ◽

Jennifer E. Jones ◽

Simon J. A. Pope

Keyword(s):

Gold Nanoparticles ◽

Water Soluble ◽

Rhenium Complexes

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Differential reactivity of the inner and outer positions of Au25(SCH2CH2Ph)18 dimeric staples under place exchange conditions

Chemical Communications ◽

10.1039/c4cc09252j ◽

2015 ◽

Vol 51 (15) ◽

pp. 3204-3207 ◽

Cited By ~ 16

Author(s):

Paolo Pengo ◽

Cristian Bazzo ◽

Mariangela Boccalon ◽

Lucia Pasquato

Keyword(s):

Exchange Reaction ◽

Differential Reactivity ◽

Site Selectivity ◽

Place Exchange

The site selectivity of the place exchange reaction at the two inequivalent positions of the neutral Au25(SCH2CH2Ph)18 staples depends on the nature of the incoming thiol.

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