Fibroblast protective effect of Royal Jelly against deleterious lipid peroxidation by-products

2013 ◽  
Vol 69 (2) ◽  
pp. e64
Author(s):  
Frederic Bonte ◽  
Marcela Otranto ◽  
Aurore Danigo ◽  
Jean Christophe Archambault ◽  
Alexis Desmouliere
Keyword(s):  
Lipid Peroxidation ◽  
Protective Effect ◽  
Royal Jelly ◽  
By Products

scholarly journals The Effect of Tin Compounds on the Lipid Peroxidation Level of Russian Sturgeon Fresh and Cryopreserved Sperm

2020 ◽  
Vol 76 (2) ◽  
pp. 34-42
Author(s):  
Margarita Kolyada ◽  
Victoria Osipova ◽  
Nadezhda Berberova ◽  
Yuri Pimenov
Keyword(s):  
Lipid Peroxidation ◽  
Protective Effect ◽  
Thiobarbituric Acid ◽  
Organotin Compounds ◽  
Russian Sturgeon ◽  
Lower Sensitivity ◽  
Tin Compounds ◽  
Cell Productivity ◽  
Cryopreserved Sperm ◽  
By Products

The effect of organotin compounds (OTs) on the accumulation of the lipid peroxidation (LPO) carbonyl by-products, which react with thiobarbituric acid (TBARS) in fresh and cryopreserved sperm of Russian sturgeon, was studied. It was found that incubation (1 hour) of Russian sturgeon sperm with OTs (CH3SnCl3, (CH3)2SnCl2, (CH3)3SnCl, (n-C4H9)2SnCl2, (n-C4H9)3SnCl, (C6H5)2SnCl2, (C6H5)3SnCl) in concentration 0.1 mM led to the promotion of the accumulation of TBARS in native semen. Dimethyl- (DMT) and diphenyltin dichlorides (DPT) exhibited the greatest promoting activity, and the LPO level of both native and cryopreserved sperm of Russian sturgeon, including those in modified Stein's cryomedium, increased in the presence of these compounds. It was found that Russian sturgeon's cryopreserved sperm had lower sensitivity to the promotion of sperm LPO by DMT and DPT compared with the native sperm. The protective effect of Stein’s cryomedium decreased in the presence of the studied OTs. The results suggest that accumulation of OTs by gonad of fish is another stress factor affecting the cell productivity in the cryopreservation process.

The Protective Effect of Royal Jelly on Roundup-Induced Immunotoxicity in Albino Rats

2012 ◽  
Vol 20 (2) ◽  
pp. 35-48
Author(s):  
Arwa Abuelfadl ◽  
Ahmad El-Ebiary ◽  
Essam Hafez ◽  
Mahmoud Salama ◽  
Mohamed Hussein
Keyword(s):  
Protective Effect ◽  
Royal Jelly ◽  
Albino Rats

Protective role of Royal Jelly (honeybee) on genotoxicity and lipid peroxidation, induced by petroleum wastewater, inAllium cepaL. root tips

2009 ◽  
Vol 30 (11) ◽  
pp. 1205-1214 ◽  
Author(s):  
Zafer Türkmen ◽  
Kültiğin Çavuşoğlu ◽  
Kürşat Çavuşoğlu ◽  
Kürşad Yapar ◽  
Emine Yalçin
Keyword(s):  
Lipid Peroxidation ◽  
Royal Jelly ◽  
Protective Role ◽  
Root Tips

scholarly journals Protective effect of dehydroepiandrosterone against lipid peroxidation in a human liver cell line

1999 ◽  
pp. 35-39 ◽  
Author(s):  
M Gallo ◽  
M Aragno ◽  
V Gatto ◽  
E Tamagno ◽  
E Brignardello ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Protective Effect ◽  
Human Liver ◽  
Antioxidant Properties ◽  
Liver Cells ◽  
Threshold Concentration ◽  
Blue Staining ◽  
Lag Phase ◽  
Human Liver Cell ◽  
Chang Liver

OBJECTIVE: Dehydroepiandrosterone (DHEA) is a widely studied steroid hormone with multi-functional properties. Reports suggest that some of the many activities of DHEA are due to its protective effect against lipid peroxidation. Nevertheless, the antioxidant properties of DHEA are still the subject of debate. The aim was to evaluate whether its two opposed effects on lipid peroxidation reported in the literature may be dependent on schedule and doses used. METHODS: Chang liver cells, a line derived from normal human liver, were grown in media containing either no steroids (control) or DHEA at concentrations ranging from 0.1 micromol/l to 50 micromol/l. At specific times, cultures were halted and cells received a pro-oxidant stimulus (cumene (CuOOH) 0.5 mmol/l), at which time cell viability (by trypan blue staining and lactate dehydrogenase (LDH) release) and thiobarbituric acid reactive substances (TBARS) concentration (spectrophotometrical assay) were evaluated. RESULTS: At concentrations ranging from 0.1 micromol/l to 1 micromol/l, DHEA protects Chang liver cells against lipid peroxidation and/or death induced by cumene. This effect disappears if the concentration is increased to 10 micromol/l; at higher concentrations (50 micromol/l) a pro-oxidant/cytotoxic effect of DHEA appears. CONCLUSIONS: DHEA exhibits two opposed effects on lipid peroxidation; depending on its concentration it acts either to limit or to induce oxidative stress. The threshold concentration at which the pro-oxidant activity of DHEA prevails is not far in excess of that having an antioxidant effect. Either effect of DHEA on lipid peroxidation is only evident after a 'lag-phase'.

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