Real-world effectiveness of MLC901 in subjects after brain injuries in the eastern European population: A preliminary result of neuroaid safe treatment (nest) registry

2021 ◽  
Vol 429 ◽  
pp. 119652
Author(s):  
Anita Anisovska ◽  
Mariusz Janta ◽  
Anna Tomašová ◽  
Slavomír Guťan ◽  
Barbora Garajová ◽  
...  
2020 ◽  
Vol 10 (8) ◽  
pp. 499
Author(s):  
Ramesh Kumar ◽  
Azizi Abu Bakar ◽  
Jegan Thanabalan ◽  
Sanmugarajah Paramasvaran ◽  
Charng Jeng Toh ◽  
...  

Background: MLC601/MLC901 (NeuroAiD™) is a combination of natural products shown to be safe and to aid neurological recovery after brain injuries, especially ischemic stroke. Few studies have investigated NeuroAiD in primary intracerebral hemorrhage (ICH). The NeuroAiD Safe Treatment (NeST) Registry explores NeuroAiD use in the real-world setting. This cohort study aimed to assess its use and safety in ICH. Methods: The online NeST Registry of subjects with ICH given NeuroAiD prospectively collected clinical data at baseline and monthly visits (V) 1 to 3. Outcome measures included compliance, side effects, Glasgow Coma Scale (GCS), National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), and Short Orientation-Memory-Concentration Test (SOMCT). Results: Sixty-six subjects were included. NeuroAiD was well-tolerated with fair compliance over three months. Two non-serious side effects were reported. Mean scores significantly improved on all outcome scales. The proportion of subjects with favorable outcomes significantly improved from baseline to V3: NIHSS 0–4, from 12% to 59% (p < 0.0001); GCS 13–15, from 64% to 88% (p = 0.007); mRS 0–1, from 9% to 37% (p = 0.004); and SOMCT score 0–8, from 44% to 68% (p = 0.029). Conclusions: NeuroAiD in the real-world setting was safe and showed potential for a sustained positive effect on neurological recovery after ICH.


Author(s):  
Patricia Gómez-Costilla ◽  
Carmen García-Prieto ◽  
Noelia Somarriba-Arechavala

AbstractThe European population is aging and their declining capacity makes older Europeans more dependent on the availability of care. Male and female health needs at older ages are different, yet there are contradictory results on the study of gender inequalities in health among the older European population. The aim of this article is twofold: first, we study whether there is a general gender health gap at older ages across Europe. Secondly, we analyze the existence of an increasing or decreasing universal association between the gender health gap and age among the older European population or whether, by contrast, this depends on the type of welfare state. To achieve these goals, we use data from the Survey on Health, Ageing and Retirement in Europe (SHARE) for respondents aged 50 and over in 2015, and we carry out several multilevel random intercept logistic regressions for European countries. Our results show that when we split European countries into groups according to the type of welfare state, we only find a significant gender health gap in older people in Southern and Social Democratic countries. Some differences have been found in the links between the gender health gap and age among European countries. Old women report worse health than men at all ages in Southern countries while in Social Democratic states it is only true for women aged 80 and over. In Bismarckian states there are barely any gender differences, while the gender health gap has no clearly defined bias. Between the ages of 60 and 79, men from Eastern European countries report poorer health, while after 80 it is women who report poorer health. In general, we found the widest gender inequalities in health for the oldest population group, especially in Southern and Eastern European countries.


2021 ◽  
Vol 429 ◽  
pp. 119651
Author(s):  
Anita Anisovska ◽  
Mariusz Janta ◽  
Anna Tomašová ◽  
Slavomír Guťan ◽  
Barbora Garajová ◽  
...  

2018 ◽  
Vol 42 (2) ◽  
pp. 196-218 ◽  
Author(s):  
Simona A. Ispas ◽  
Dragos Iliescu

To date, there are no scales measuring work–home interaction which are adapted for the Eastern European population. Owing to the significantly different sociocultural contexts and geopolitical history between Western and Eastern populations, despite the massive contemporary East–West migration, a more culturally appropriate scale is needed to ensure valid and reliable measurement of the construct. This article presents the adaptation of the Survey Work–Home Interaction—NijmeGen (SWING) for the Romanian population. The results show that SWING can successfully measure work–home interaction for this population. Gender equivalence is also discussed.


2008 ◽  
Vol 23 (7) ◽  
pp. 2228-2234 ◽  
Author(s):  
A. Covic ◽  
A. Schiller ◽  
N.-G. Mardare ◽  
L. Petrica ◽  
M. Petrica ◽  
...  

2013 ◽  
Vol 69 (11) ◽  
pp. 1901-1907 ◽  
Author(s):  
Tudor Radu Pop ◽  
Ştefan Cristian Vesa ◽  
Adrian Pavel Trifa ◽  
Sorin Crişan ◽  
Anca Dana Buzoianu

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