Changes in actin and E-cadherin expression induced by 5-aminolevulinic acid photodynamic therapy in normal and Ras-transfected human mammary cell lines

2012 ◽  
Vol 106 ◽  
pp. 47-52 ◽  
Author(s):  
G. Di Venosa ◽  
L. Rodriguez ◽  
L. Mamone ◽  
L. Gándara ◽  
M.V. Rossetti ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cell Lines ◽  
Aminolevulinic Acid ◽  
Mammary Cell ◽  
E Cadherin

scholarly journals Aminolevulinic Acid-Mediated Photodynamic Therapy of Human Meningioma: An in Vitro Study on Primary Cell Lines

2015 ◽  
Vol 16 (12) ◽  
pp. 9936-9948 ◽  
Author(s):  
Mustafa El-Khatib ◽  
Carolin Tepe ◽  
Brigitte Senger ◽  
Maxine Dibué-Adjei ◽  
Markus Riemenschneider ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cell Lines ◽  
Aminolevulinic Acid ◽  
In Vitro Study ◽  
Vitro Study ◽  
Primary Cell ◽  
Human Meningioma ◽  
Primary Cell Lines

scholarly journals Mechanism of Differential Susceptibility of Two (Canine Lung Adenocarcinoma) Cell Lines to 5-Aminolevulinic Acid-Mediated Photodynamic Therapy

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4174
Author(s):  
Tomohiro Osaki ◽  
Narumi Kunisue ◽  
Urara Ota ◽  
Hideo Imazato ◽  
Takuya Ishii ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Lung Adenocarcinoma ◽  
Cell Lines ◽  
Aminolevulinic Acid ◽  
Malignant Tumors ◽  
Protoporphyrin Ix ◽  
Invasive Treatment ◽  
No Donor ◽  
Adenocarcinoma Cell ◽  
Significant Difference

Photodynamic therapy (PDT) is a clinically approved, minimally invasive treatment for malignant tumors. Protoporphyrin IX (PpIX), derived from 5-aminolevulinic acid (5-ALA) as the prodrug, is one of the photosensitizers used in PDT. Recently, we reported a significant difference in response to 5-ALA-mediated PDT treatment in two canine primary lung adenocarcinoma cell lines (sensitive to PDT: HDC cells, resistant to PDT: LuBi cells). This study aimed to examine the difference in cytotoxicity of 5-ALA-mediated PDT in these cells. Although intracellular PpIX levels before irradiation were similar between HDC and LuBi cells, the percentage of ROS-positive cells and apoptotic cells in LuBi cells treated with 5-ALA-mediated PDT was significantly lower than that in HDC cells treated with 5-ALA-mediated PDT. A high dosage of the NO donor, DETA NONOate, significantly increased the cytotoxicity of 5-ALA-mediated PDT against LuBi cells. These results suggest that the sensitivity of 5-ALA-mediated PDT might be correlated with NO.

Selective inhibition of ferrochelatase by 5-aminolevulinic acid-based photodynamic therapy in human cell lines

1999 ◽  
Vol 11 (12) ◽  
pp. A75
Author(s):  
P. Hinnen ◽  
F. W.M. de Rooji ◽  
A. Edixhoven ◽  
E. M. Terlouw ◽  
J. H.P. Wilson ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cell Lines ◽  
Human Cell ◽  
Aminolevulinic Acid ◽  
Selective Inhibition ◽  
Human Cell Lines

5-aminolevulinic acid (ALA) mediated photodynamic therapy of bladder cancer cell lines

1999 ◽  
Author(s):  
Sonja Fickweiler ◽  
Rene C. Krieg ◽  
Herbert G. Stepp ◽  
Ferdinand Hofstaedter ◽  
Ruth Knuechel
Keyword(s):  
Bladder Cancer ◽  
Photodynamic Therapy ◽  
Cell Lines ◽  
Cancer Cell ◽  
Aminolevulinic Acid ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell

Delta-aminolevulinic acid-mediated photosensitization of prostate cell lines: Implication for photodynamic therapy of prostate cancer

The Prostate ◽  
1998 ◽  
Vol 36 (4) ◽  
pp. 211-218 ◽  
Author(s):  
Pradip Chakrabarti ◽  
Eduardo Orihuela ◽  
Norman Egger ◽  
Durwood E. Neal ◽  
Rama Gangula ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Photodynamic Therapy ◽  
Cell Lines ◽  
Aminolevulinic Acid ◽  
Prostate Cell ◽  
Prostate Cell Lines

Protoporphyrin IX Fluorescence Photobleaching and the Response of Rat Barrett's Esophagus Following 5-aminolevulinic Acid Photodynamic Therapy

2006 ◽  
Vol 82 (6) ◽  
pp. 1638 ◽  
Author(s):  
Ingrid A. Boere ◽  
Dominic J. Robinson ◽  
Henriette S. de Bruijn ◽  
Jolanda Kluin ◽  
Hugo W. Tilanus ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Aminolevulinic Acid ◽  
Protoporphyrin Ix
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