Prevalence and factors associated with depressive illness in patients with tuberculosis in Mulago hospital, Kampala- Uganda: A cross sectional study

Author(s):  
Racheal Alinaitwe ◽  
Caroline Birungi ◽  
Paul Bangirana ◽  
Noeline Nakasujja
BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e022338
Author(s):  
Ritah Bakesiima ◽  
Pauline Byakika-Kibwika ◽  
James K Tumwine ◽  
Joan N Kalyango ◽  
Gloria Nabaasa ◽  
...  

ObjectiveTo determine the prevalence and factors associated with dyslipidaemias in women using hormonal contraceptives.DesignCross-sectional studySettingMulago Hospital, Kampala, UgandaParticipantsThree hundred and eighty-four consenting women, aged 18–49 years, who had used hormonal contraceptives for at least 3 months prior to the study.Study outcomeDyslipidaemias (defined as derangements in lipid profile levels which included total cholesterol ≥200 mg/dL, high-density lipoprotein <40 mg/dL, triglyceride >150 mg/dL or low-density lipoprotein ≥160 mg/dL) for which the prevalence and associated factors were obtained.ResultsThe prevalence of dyslipidaemias was 63.3% (95% CI: 58.4 to 68.1). Body mass index (BMI) (PR=1.33, 95% CI: 1.15 to 1.54, p<0.001) and use of antiretroviral therapy (ART) (PR=1.21, 95% CI: 1.03 to 1.42, p=0.020) were the factors significantly associated with dyslipidaemias.ConclusionDyslipidaemias were present in more than half the participants, and this puts them at risk for cardiovascular diseases. The high-risk groups were women with a BMI greater than 25 Kg/m2and those who were on ART. Therefore, lipid profiles should be assessed in women using hormonal contraceptives in order to manage them better.


2020 ◽  
Author(s):  
Ivan Mubangizi ◽  
Etheldreda Nakimuli-Mpungu ◽  
Ismael Kawooya ◽  
Christine Sekaggya-wiltshire

Abstract BACKGROUND Depression among patients with sickle cell disease (SCD) is under diagnosed and undertreated due to the overlap of symptoms and signs of SCD and depression. The study sought to determine the prevalence and factors associated with depression among adults attending the SCD out-patient clinic in Mulago Hospital, Uganda. METHODS This was a cross sectional study in which 255 adults with SCD were enrolled. Participants were evaluated for depression using the Self Report Questionnaire (SRQ-20) and a score of 6 was considered diagnostic of depression. Demographic data was collected with a pre-tested study questionnaire. Perceived social support was measured using the 12-item multidimensional social support scale and, self-esteem was measured using the Rosenberg Self-Esteem Scale. Blood samples were taken to obtain a complete blood count. Modified poisson regression analyses were used to determine associations of depression. RESULTS The prevalence of depression was 68.2% (95% C.I; 62–74) with a median age of 21 years. The factors independently associated with depression were pain crisis in the last month (prevalence ratio (PR) = 1.07, 95% CI: 1.04–1.07, p = 0.001), history of a hospital admission in the past 6 months (PR = 1.04, 95% CI: 1.01–1.07, p = 0.012), formal education (PR = 0.79, 95% CI: 0.59–0.97, P = 0.008) and a low social support rating (PR = 0.67, 95% CI: 0.53–0.84, P = 0.0019) CONCLUSIONS The prevalence of depression in adults with SCD is high with up to two thirds of patients having some form of depression. The major risk factors were low level of education, low social support, pain crises in the past month and hospital admissions in the last 6 months.


2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Rebecca Nantanda ◽  
Marianne S Ostergaard ◽  
Grace Ndeezi ◽  
James K Tumwine

2019 ◽  
Author(s):  
alfred ogwal ◽  
felix oyania ◽  
emmanuel nkonge ◽  
timothy kabanda makumbi ◽  
fred moses galukande

Abstract Background: Cancellation of elective surgical procedures has been noted to waste resources and with potential to increase morbidity and mortality among patients. This study set out to determine the prevalence and factors associated with cancellation of elective surgical procedures at Mulago Hospital. Methods: A prospective cross-sectional study was conducted from 10 th January 2018 to 20 th February 2018. We recruited patients of all ages admitted on surgical wards and scheduled for elective surgery. Demographic data, diagnosis, specialty of surgery, proposed surgery, theatre and reasons for cancellation were extracted and analyzed using logistic regression. Results: There were 115 procedures canceled out of 400 cases, giving us a prevalence of cancellation of 28.8%. Neurosurgery had the highest cancellation rate at 46.8% (n=29), OR = 2.23, 95% CI (1.22, 4.06). UCI theatre was about two times more likely to have a procedure canceled (OR = 2.12, 95% CI, 0.91-4.96). Facility factors contributed 67.8% to overall cancellations. Commonest reason for case cancellations was theatre time run out. There was no procedure canceled due to lack of ICU bed. There was a significant association between specialty and surgical cancellation rate (p < 0.05). Conclusions: The prevalence of cancellation of elective surgical procedures in Mulago Hospital is 28.8% with Neurosurgery having the highest cancellation rate. Two thirds of the factors responsible for procedure cancellations were facility related with more than fifty percent of them being potentially preventable. Quality improvement strategies are necessary in those sub specialties susceptible to procedure cancellations due to facility factors. Keywords: cancellation; elective procedures; factors; prevalence


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