Erectile Dysfunction is a Modifiable Risk Factor for Major Depressive Disorder: Analysis of a Federated Research Network

2021 ◽  
Vol 18 (12) ◽  
pp. 2005-2011
Author(s):  
Sirpi Nackeeran ◽  
Amoghavarsha Havanur ◽  
Jesse Ory ◽  
Stanley Althof ◽  
Ranjith Ramasamy



2009 ◽  
Vol 249 (2) ◽  
pp. 354
Author(s):  
Laurel A. Copeland ◽  
Valerie A. Lawrence ◽  
John E. Zeber


Cephalalgia ◽  
2015 ◽  
Vol 36 (5) ◽  
pp. 493-498 ◽  
Author(s):  
Jong-Geun Seo ◽  
Sung-Pa Park

Background Almost one-third of patients with migraine do not adequately respond to triptans. We examined factors contributing to frovatriptan response in patients with migraine. Methods We enrolled new patients with migraine who consecutively visited our headache clinic. Eligible patients were instructed to take 2.5 mg of frovatriptan as soon as possible after migraine attack. The responsiveness was determined by whether headache was relieved or absent within 4 hours after the intake of frovatriptan. We assessed frovatriptan to be efficacious when headache responded to its administration in at least one of two successive migraine attacks and inefficacious when headache was not relieved in either attack. We included demographic, clinical and psychiatric variables in the analysis of factors associated with frovatriptan response. Results Of 128 eligible patients, 28 (21.9%) experienced frovatriptan inefficacy. In 24 patients with current major depressive disorder, 12 (50.0%) had frovatriptan inefficacy. Only current major depressive disorder was identified as a risk factor for inefficacy (odds ratio = 5.500, 95% confidence interval 2.103–14.382, p = 0.001). Conclusions Depression may be a risk factor of frovatriptan inefficacy in patients with migraine, even though half of patients with major depressive disorder respond to frovatriptan.



2017 ◽  
Vol 43 (5) ◽  
pp. 1128-1137 ◽  
Author(s):  
Xiao Xiao ◽  
Fanfan Zheng ◽  
Hong Chang ◽  
Yina Ma ◽  
Yong-Gang Yao ◽  
...  


2013 ◽  
Vol 210 (2) ◽  
pp. 601-606 ◽  
Author(s):  
Shiau-Shian Huang ◽  
Ching-Heng Lin ◽  
Chin-Hong Chan ◽  
El-Wui Loh ◽  
Tsuo-Hung Lan


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