Is Type 2 Diabetes Mellitus a Predictive Factor for Incontinence After Laparoscopic Radical Prostatectomy? A Matched Pair and Multivariate Analysis

2010 ◽  
Vol 183 (3) ◽  
pp. 1087-1091 ◽  
Author(s):  
Dogu Teber ◽  
Mustafa Sofikerim ◽  
Mutlu Ates ◽  
Ali Serdar Gözen ◽  
Oguz Güven ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Multivariate Analysis ◽  
Radical Prostatectomy ◽  
Predictive Factor ◽  
Laparoscopic Radical Prostatectomy ◽  
Matched Pair

scholarly journals Gut microbiota imbalances in Tunisian participants with type 1 and type 2 diabetes mellitus

2019 ◽  
Vol 39 (6) ◽  
Author(s):  
Meriem Fassatoui ◽  
Mireia Lopez-Siles ◽  
Diana A. Díaz-Rizzolo ◽  
Haifa Jmel ◽  
Chokri Naouali ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Multivariate Analysis ◽  
Gut Microbiota ◽  
Glycated Hemoglobin ◽  
Statistical Tests ◽  
Treatment Of Diabetes

Abstract Gut microbiota plays an important role in the regulation of the immune system and host’s metabolism. We aimed to characterize the gut microbiota of Tunisian participants with and without diabetes. We enrolled ten participants with type 1 diabetes mellitus (T1DM), ten patients with type 2 diabetes mellitus (T2DM), and 11 subjects without diabetes. Bacteria was quantified in fecal samples by quantitative PCR (qPCR). Statistical tests and multivariate analysis were performed using RStudio program. Results showed that the proportions of Firmicutes, Akkermansia muciniphila, and Faecalibacterium prausnitzii (P≤0.041), as well as, the ratio Firmicutes/Bacteroidetes decreased in participants with T1DM compared with those without diabetes (p = 0.036). Participants with T2DM presented a reduction in the amounts of A. muciniphila and F. prausnitzii compared with those without diabetes (P≤0.036). Furthermore, A muciniphila is negatively correlated with glucose level (P=0.022) and glycated hemoglobin (HbA1c) (P=0.035). Multivariate analysis revealed that participants with diabetes formed a cluster apart compared with those without diabetes. In conclusion the gut bacteria of Tunisian participants with diabetes was altered. The gut bacterial profile, especially the distribution of A muciniphila in participants with diabetes was affected by glycemic dysregulation. The investigation of the gut microbiota may help clinicians to improve diagnosis and treatment of diabetes and its complications.

scholarly journals Peran Riwayat Ayah Diabetes Melitus Tipe 2 pada Status Prediabetes Anak Kandung Penderita Diabetes Melitus Tipe 2

2020 ◽  
Vol 6 (4) ◽  
pp. 182
Author(s):  
Maulidia Ekaputri ◽  
Henrico Citrawijaya ◽  
Kevin Jonathan Adhimulia ◽  
Adrian Reynaldo Sudirman ◽  
Radityo Ali Murti ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Multivariate Analysis ◽  
Global Physical Activity Questionnaire ◽  
History Of ◽  
Activity Questionnaire ◽  
Diabetes Melitus

Pendahuluan. Pasien diabetes melitus tipe 2 (DMT2) pada umumnya memiliki satu atau lebih komplikasi kronik pada saat terdiagnosis. Deteksi dini dan pencegahan sangat penting untuk mengurangi angka mortalitas dan morbiditas terkait DMT2, terutama pada kelompok dengan risiko tinggi seperti anak penderita DMT2. Studi ini bertujuan untuk mencari faktor-faktor yang berkaitan dengan status prediabetes pada anak dari penderita diabetes melitus tipe 2.Metode. Studi ini merupakan studi potong lintang yang melibatkan 54 anak dari penderita DMT2. Subjek dikumpulkan secara konsekutif. Status prediabetes ditentukan melalui HbA1C berstandar national glycohemoglobin standardization program (NGSP). Aktivitas fisik ditentukan melalui kuisioner global physical activity questionnaire (GPAQ)-versi Bahasa Indonesia. Tekanan darah dan data antropometrik diukur secara langsung. Analisis bivariat dan multivariat dilakukan dengan IBM SPSS 23.Hasil. Dilakukan analisis terhadap 54 subjek. Mayoritas subjek adalah perempuan (79,6%) dan rerata umur adalah 38,8 tahun. Proporsi prediabetes mencapai 31,5%. Analisis multiavariat menunjukkan hubungan bermakna antara riwayat paternal DMT2 (adjusted OR 7,520; IK 95%=1,071-52,784), lingkar pinggang berisiko (adjusted OR 5,482; IK 95%=1,019-29,504) terhadap status prediabetes.Simpulan. Riwayat paternal DMT2 dan lingkar pinggang berkaitan dengan status prediabetes pada anak dari penderita DMT2.Kata Kunci: Anak penderita DM tipe 2, HbA1C, intoleransi glukosa, prediabetes The Role of Paternal History of Type 2 Diabetes Mellitus on Prediabetes Status among The Offspring of Type 2 Diabetes Mellitus Patients Introduction. Since patients with type 2 diabetes mellitus (T2DM) often present with one or more chronic complications, at the time of diagnosis, early detection and prevention is essential to reduce T2DM-associated mortality and morbidity, espescially among high risk population such as the offspring of T2DM. This study aimed to investigate several factors associated with prediabetes status among the offsprings of T2DM patients.Methods. A cross-sectional study was conducted involving 54 offsprings of T2DM patients. Subjects were recruited consecutively. We collected demographic data, anthropometric measurement, blood pressure, and HbA1c level. Physical activity were assessed by using Indonesian version of global physical activity questionnaire (GPAQ). Prediabetes status was investigated by standardized national glycohemoglobin standardization program (NGSP) HbA1c. Bivariate statistical and multivariate analysis was performed by using IBM SPSS 23.Results: The majority of subjects were female (79.6%) and the mean age was 38.8 years old. The proportion of prediabetes was 31.5%. Multivariate analysis showed significant association among paternal history of T2DM (adjusted OR 7.520; 95%CI=1.071-52.784), waist circumference at risk (adjusted OR 5.482; 95%CI=1.019-29.504), and prediabetes status.Conclusion: Paternal history of T2DM and waist circumference were associated with prediabetes status among the offspring of T2DM patients.

scholarly journals Diagnostic significance of serum lncRNA HOTAIR and its predictive value for the development of chronic complications in patients with type 2 diabetes mellitus

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Huiyun Wang ◽  
Yu Xia ◽  
Yanxia Zhang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Multivariate Analysis ◽  
Fasting Blood Glucose ◽  
Pcr Analysis ◽  
Healthy Controls ◽  
Chronic Complications ◽  
Qrt Pcr

Abstract Background Type 2 diabetes mellitus (T2DM) affects the social economy and quality of life, and has become a major threat to human health. This observation aimed to study the possibility of serum HOTAIR as a diagnostic index in patients with T2DM and to explore the prognostic potential of HOTAIR in the development of T2DM. Methods The expression of HOTAIR in serum of 96 patients with T2DM and 82 healthy controls was detected by the qRT-PCR technique. The related biochemical indexes of all participants were determined, such as total cholesterol (TC) and fasting blood glucose (FBG). The value of serum HOTAIR in the diagnosis of T2DM in the two groups was analyzed by the ROC curve. Moreover, the prognostic value of HOTAIR on T2DM was examined by the K-M curve and COX multivariate analysis. Results The results of the qRT-PCR analysis showed that the serum level of HOTAIR in patients with T2DM was significantly higher than that in healthy controls. ROC analysis showed that HOTAIR in serum was a diagnostic factor of T2DM. Further multivariate analysis showed that HOTAIR could be an independent biomarker in the prediction of chronic complications for T2DM patients, such as diabetic retinopathy and diabetic nephropathy. Conclusions We found the augment of HOTAIR expression was a character of T2DM. The high expression of serum HOTAIR was a potential non-invasive diagnostic marker and independent prognostic factor in patients with T2DM.

scholarly journals Lack of Association of Coffee Consumption with the Prevalence of Self-Reported Type 2 Diabetes Mellitus in a Mexican Population: A Cross-Sectional Study

2018 ◽  
Vol 15 (10) ◽  
pp. 2100
Author(s):  
Ana Gil-Madrigal ◽  
Thelma González-Castro ◽  
Carlos Tovilla-Zárate ◽  
Daniela Aguilar-Velázquez ◽  
Tania Gómez-Peralta ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Multivariate Analysis ◽  
Coffee Consumption ◽  
Daily Consumption ◽  
Coffee Intake ◽  
Southeastern Part ◽  
Cross Sectional

It is estimated that almost 366 million people are currently suffering from diabetes mellitus worldwide. However, it has been suggested that coffee consumption has a protective effect against the development of type 2 diabetes mellitus. This association has been observed in many regions around the world. Today, there are no reports in Mexico regarding this association. Therefore, the aim of this study was to assess the association between coffee intake and self-reported type 2 diabetes mellitus in the southeastern part of Mexico. This study included 1277 residents of Comalcalco, a municipality of Tabasco State, Mexico. We calculated the prevalence for diabetes and performed multivariate analysis using multiple logistic regressions to evaluate the combined association with type 2 diabetes mellitus. The prevalence of the diabetes was 12.52% (95% CI: 10.67–14.38). The majority of people surveyed (77.29%; 95% CI: 74.95–79.60) indicated they were coffee drinkers. The results of multivariate analysis showed a non-significant relationship between the number of cups of coffee drank and type 2 diabetes mellitus. The adjusted odds ratio gave the following values: 1.20, (95% CI: 0.59–2.41) for non-daily consumption; 1.66 (0.82–3.34), for 1 cup of coffee peer day, and 1.49 (0.78–2.86) for 2–3 cups. Subsequently, an adjustment was made for age, gender, marital status, education, alcohol consumption, and cigarette smoking. In our population, we did not observe an association between coffee intake and its protective relationship with self-reported type 2 diabetes mellitus.

Does Type 2 Diabetes Mellitus Have an Impact on Postoperative Early, Mid-Term and Late-Term Urinary Continence After Robot-Assisted Radical Prostatectomy?

2019 ◽  
Vol 33 (3) ◽  
pp. 201-206
Author(s):  
Serdar Cakmak ◽  
Abdullah Erdem Canda ◽  
Kemal Ener ◽  
Ali Fuat Atmaca ◽  
Serkan Altinova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Radical Prostatectomy ◽  
Urinary Continence ◽  
Robot Assisted
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