243 EMPIRICAL ESTIMATE OF THE LEAD TIME DISTRIBUTION FOR PROSTATE CANCER BASED ON TWO INDEPENDENT REPRESENTATIVE COHORTS OF MEN NOT SUBJECT TO PSA-SCREENING

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Caroline Savage ◽  
Hans Lilja ◽  
David Ulmert ◽  
Anders Bjartell ◽  
Anders Dahlin ◽  
...  
2006 ◽  
Vol 175 (4S) ◽  
pp. 477-478 ◽  
Author(s):  
Kazuto Ito ◽  
Takumi Yamamoto ◽  
Hiroyuki Takechi ◽  
Kazuhiro Suzuki

2006 ◽  
Vol 175 (4S) ◽  
pp. 155-155
Author(s):  
Robert L. Grubb ◽  
David L. Levin ◽  
Paul F. Pinsky ◽  
Jerome Mabie ◽  
Thomas L. Riley ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 359
Author(s):  
Takahiro Kimura ◽  
Shun Sato ◽  
Hiroyuki Takahashi ◽  
Shin Egawa

The incidence of prostate cancer (PC) has been increasing in Asian countries, where it was previously low. Although the adoption of a Westernized lifestyle is a possible explanation, the incidence is statistically biased due to the increase in prostate-specific antigen (PSA) screening and the accuracy of national cancer registration systems. Studies on latent PC provide less biased information. This review included studies evaluating latent PC in several countries after excluding studies using random or single-section evaluations and those that did not mention section thickness. The findings showed that latent PC prevalence has been stable since 1950 in Western countries, but has increased over time in Asian countries. Latent PC in Asian men has increased in both prevalence and number of high-grade cases. Racial differences between Caucasian and Asian men may explain the tumor location of latent PC. In conclusion, the recent increase in latent PC in Asian men is consistent with an increase in clinical PC. Evidence suggests that this increase is caused not only by the increase in PSA screening, but also by the adoption of a more Westernized lifestyle. Autopsy findings suggest the need to reconsider the definition of clinically insignificant PC.


2001 ◽  
Vol 17 (3) ◽  
pp. 329-337 ◽  
Author(s):  
Matthias Perleth ◽  
Reinhard Busse ◽  
Bernhard Gibis ◽  
Angela Brand

Objective: In this article, three preventive strategies—mammography screening for breast cancer, PSA screening for prostate cancer, and routine ultrasound in normal pregnancy—are discussed in the context of German health care.Methods: Epidemiologic data and German studies evaluating different aspects of these preventive measures were identified and analyzed.Results: Only a few studies could be identified that investigate these preventive measures. Despite sufficient evidence, in part derived from a German study, there is not yet a mammography screening program. In contrast, ultrasound in pregnancy is offered routinely, although there are controversies regarding the benefit of this practice. PSA screening is not offered as part of the screening program for prostate cancer. However, PSA tests as well as mammographies are done in large numbers in German ambulatory care—a practice that could be considered wild or opportunistic screening.Conclusions: These case studies show that preventive programs and practices in Germany are not sufficiently based on sound evidence. The paucity of evaluation activities related to prevention in Germany is probably due to the low threshold to introduce new preventive programs into the German healthcare system in the past.


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