scholarly journals Preferences for Route of Administration, Frequency and Location – A Time-Trade-Off Study in the United Kingdom General Population

2017 ◽  
Vol 20 (9) ◽  
pp. A637
Author(s):  
T Jørgensen ◽  
M Worbes-Cerezo ◽  
F Lelli ◽  
XY Lee ◽  
M Bøgelund ◽  
...  
Author(s):  
Di Long ◽  
Suzanne Polinder ◽  
Gouke J. Bonsel ◽  
Juanita A. Haagsma

Abstract Purpose To assess the test–retest reliability of the EQ-5D-5L and the reworded Quality of Life After Traumatic Brain Injury Overall Scale (QOLIBRI-OS) for the general population of Italy, the Netherlands, and the United Kingdom (UK). Methods The sample contains 1864 members of the general population (aged 18–75 years) of Italy, the Netherlands, and the UK who completed a web-based questionnaire at two consecutive time points. The survey included items on gender, age, level of education, occupational status, household annual income, chronic health status, and the EQ-5D-5L and reworded QOLIBRI-OS instrument. Test–retest reliability of the EQ-5D-5L dimensions, EQ-5D-5L summary index, EQ VAS, reworded QOLIBRI-OS dimensions and reworded QOLIBRI-OS level sum score was examined by Gwet’s Agreement Coefficient (Gwet’s AC) and Intraclass Correlation Coefficient (ICC). Results Gwet’s AC ranged from 0.64 to 0.97 for EQ-5D-5L dimensions. The ICC ranged from 0.73 to 0.84 for the EQ-5D-5L summary index and 0.61 to 0.68 for EQ VAS in the three countries. Gwet’s AC ranged from 0.35 to 0.55 for reworded QOLIBRI-OS dimensions in the three countries. The ICC ranged from 0.69 to 0.77 for reworded QOLIBRI-OS level sum score. Conclusion Test–retest reliability of the EQ-5D-5L administered via a web-based questionnaire was substantial to almost perfect for the EQ-5D-5L dimensions, good for EQ-5D-5L summary index, and moderate for the EQ VAS. However, test–retest reliability was less satisfactory for the reworded QOLIBRI-OS. This indicates that the web-based EQ-5D-5L is a reliable instrument for the general population, but further research of the reworded QOLIBRI-OS is required.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sarah Daimer ◽  
Lorenz Mihatsch ◽  
Lisa Ronan ◽  
Graham K. Murray ◽  
Franziska Knolle

Studies reported a strong impact on mental health during the first wave of the COVID-19 pandemic in March–June, 2020. In this study, we assessed the impact of the pandemic on mental health in general and on schizotypal traits in two independent general population samples of the United Kingdom (May sample N: 239, October sample N: 126; participation at both timepoints: 21) and in two independent general population samples of Germany (May sample N: 543, October sample N: 401; participation at both timepoints: 100) using online surveys. Whereas general psychological symptoms (global symptom index, GSI) and percentage of responders above clinical cut-off for further psychological investigation were higher in the May sample compared to the October sample, schizotypy scores (Schizotypal Personality Questionnaire) were higher in the October sample. We investigated potential associations, using general linear regression models (GLM). For schizotypy scores, we found that loneliness, use of drugs, and financial burden were more strongly corrected with schizotypy in the October compared to the May sample. We identified similar associations for GSI, as for schizotypy scores, in the May and October samples. We furthermore found that living in the United Kingdom was related to higher schizotypal scores or GSI. However, individual estimates of the GLM are highly comparable between the two countries. In conclusion, this study shows that while the general psychological impact is lower in the October than the May sample, potentially showing a normative response to an exceptional situation; schizotypy scores are higher at the second timepoint, which may be due to a stronger impact of estimates of loneliness, drug use, and financial burden. The ongoing, exceptional circumstances within this pandemic might increase the risk for developing psychosis in some individuals. The development of general psychological symptoms and schizotypy scores over time requires further attention and investigation.


Author(s):  
Tom McKenzie ◽  
Alasdair C Rutherford

We study the relationship between career concerns and shared values empirically using employee–employer matched data for the United Kingdom and overtime hours as a proxy for hard work. In line with standard career-concerns theory, we find that employees work less overtime the longer they have been with their current employer. We also find that employees who agree strongly with the statement ‘I share many of the values of my organisation’ do roughly 20% more overtime than the rest. Our results suggest the existence of a trade-off between career concerns and shared values. We begin to consider some potential implications of this for employee recruitment as well as for the design of career paths across the private, public and voluntary sectors.


1977 ◽  
Vol 5 (6) ◽  
pp. 115-119
Author(s):  
J F Donald ◽  
M S Gatley ◽  
G Kagan ◽  
G B Leslie ◽  
R H G McKay ◽  
...  

In a multicentre evaluation in general practice involving 104 patients, Syndol, a formulation containing paracetamol, codeine phosphate, caffeine, and doxylamine succinate, was shown to be highly effective in treating the organic and psychogenic symptoms of Tension Headache in 81·7% of patients. The evaluation was performed in six widely differing practices in the United Kingdom. The result confirms the findings of other investigators in South Africa both in the efficacy of the drug and the incidence of Tension Headache in the general population. Drowsiness was the most common side-effect, indicating that the formulation provided sufficient calmative activity, especially in those patients where tension was a major component of their symptoms.


Author(s):  
Jan Busschbach ◽  
Tom Weijnen ◽  
Martin Nieuwenhuizen ◽  
Siem Oppe ◽  
Xavier Badia ◽  
...  

2001 ◽  
Vol 4 (2b) ◽  
pp. 647-657 ◽  
Author(s):  
J Landman ◽  
JK Cruickshank

AbstractObjectives:To identify lessons from and gaps in research on diet-disease links among former migrants in the United Kingdom (UK).Results:Migrant status and self-identified ethnicity do not match so these terms mask differences in social, nutritional and health status within and between population groups. Some former migrants differ in causes of death from the general population, e.g.: fewer coronary heart disease deaths among Caribbean-born; fewer cancer deaths among Caribbean, South Asian- and East African-born adults. Irish- and Scottish-born have higher mortality from all causes. Experience of risk factors differ also, e.g.: higher prevalences of hypertension and diabetes in Caribbean- and South Asian-born adults than representative samples of the general population; obesity and raised waist-hip circumference ratios in South Asian, African-Caribbean and some Irish-born adults. Former migrants experience long-term disadvantage, associated with more self-defined illness and lower reported physical activity. Nutrient intake data from the few, recent, small-scale studies must be interpreted with caution due to methodological diversity. However, second generation offspring of former migrants appear to adopt British dietary patterns, increasing fat and reducing vegetable, fruit and pulse consumption compared with first generation migrants.Conclusions:There is insufficient evidence on why some former migrants but not others experience lower specific mortality than the general population. Dietary intake variations provide important clues particularly when examined by age and migration status. Majority ethnic and younger migrant groups could raise and sustain high fruit and vegetable intakes but lower proportions of fat, by adopting many dietary practices from older migrants. Objective measures of physical activity and longitudinal studies of diets among different ethnic groups are needed to explain diversity in health outcomes and provide for evidence-based action.


2003 ◽  
Vol 36 (3) ◽  
pp. 579-599 ◽  
Author(s):  
C. J. Pattie ◽  
R. J. Johnston

Aggregate cross-national analyses of political participation have reported correlations between civic literacy, political knowledge and election turnout. Enhancing civic literacy among Canadian voters, in part by encouraging greater newspaper readership in the general population, has been put forward as a strategy for combating falling turnout in national general elections. The idea is evaluated comparatively at the level of individual voters, using data from the British Election Study. Newspaper readership is related to political knowledge, but increased newspaper reading does not translate into a greater propensity to vote.


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