scholarly journals PCV60 PREVALENCE, RISK FACTORS, AND MANAGEMENT OF UNCONTROLLED HYPERTENSION AMONG DIABETIC PATIENTS: A HOSPITAL-BASED CROSS-SECTIONAL STUDY

2020 ◽  
Vol 23 ◽  
pp. S101
Author(s):  
Z.S. Almalki
Author(s):  
SARASWATI PRADIPTA ◽  
HERI WIBOWO ◽  
DANTE SAKSONO HARBUWONO ◽  
EKOWATI RAHAJENG ◽  
RAHMA AYU LARASATI ◽  
...  

Objective: Type 2 diabetes mellitus (T2DM) patients tend to have abnormal lipid profiles, explaining the association between elevated cholesterol andtriglyceride levels in diabetic patients and coronary heart disease. This study aims to evaluate how the common risk factors for dyslipidemia affectthe lipid profile of diabetic patients and to determine which factors can be used as predictors for the occurrence of dyslipidemia in T2DM patients.Methods: A total of 238 diabetic patients (63 male and 175 female; age: 31–70 years) were enrolled in this cross-sectional study. All of them hadundergone regular examinations in cohort studies on risk factors for non-communicable diseases conducted by the Ministry of Health in Bogorbetween December 2017 and January 2018.Results: The result found that age differences did not affect lipid profile levels, and the females had higher mean values of body mass index (p<0.001),total cholesterol (TC) (p<0.05), and high-density lipoprotein (HDL) (p<0.001) than the males. The most common occurrences of dyslipidemia werehigh TC level (57.1%), followed by high low-density lipoprotein (LDL) level (47.1%), high triglyceride level (37.4%), and low HDL level (16.4%). Beingoverweight was found to be the best predictor of dyslipidemia.Conclusion: The results of this study suggest that in T2DM patients, sex affects TC and HDL levels, whereas age does not exert a significant effect onthe lipid profiles. In addition, poor glycemic control, hypertension, and obesity may serve as predictors of dyslipidemia in T2DM patients.


2020 ◽  
Vol 16 (4) ◽  
pp. 402-409 ◽  
Author(s):  
Nalini Mathala ◽  
Annapurna Akula ◽  
Sharat Hegde ◽  
Raghava Bitra ◽  
Virender Sachedev

Aim: The aim of this study is to examine the relationship between inflammatory markers, and diabetic retinopathy in type II diabetic patients. Methods: The study was a cross-sectional study included 150 type 2 diabetic patients who were divided into 3 groups. 50 in each group are divided as Diabetic patients without retinopathy (DM, n=50), nonproliferative diabetic retinopathy patients (NPDR, n=50), proliferative diabetic retinopathy patients (PDR, n=50). All the patients were subjected to complete clinical examination and laboratory investigations, such as fasting and postprandial blood glucose, serum creatinine, lipid profile tests, glycosylated haemoglobin (HbA1c), fasting insulin, serum inflammatory markers (TNF-alpha, C-reactive protein) and serum VEGF. Results: The study revealed from the multivariate analysis that age, duration and WHR (waist-hip ratio) are potent risk factors responsible for the risk of Diabetic retinopathy. Similarly, serum creatinine, CRP, TNF- alpha and VEGF are significantly higher in diabetic patients with retinopathy compared to diabetic patients without retinopathy. Conclusion: The study concluded that inflammation was associated with severe diabetic retinopathy in patients with well-controlled diabetes. A possible relationship was provided between the risk factors and biomarkers which are responsible for Diabetic retinopathy. Hence, modifying the risk factors risk and development of severe diabetic retinopathy can be reduced.


2019 ◽  
Vol 6 (10) ◽  
pp. 751-756
Author(s):  
Jayasree Chandrasekharan Nair Saradamma ◽  
Athira Thekke Kottarath ◽  
Ankitha Saleem ◽  
Asha Thulaseedharan Jaya ◽  
Aleesha Thaj

Author(s):  
Omyma Abbas Banaga Salih ◽  
Ehab Hamed

Background: Diabetic patients are at increased risk of glaucoma compared to the general population. Risk factors for glaucoma that is specific to diabetic patients include increased IOP, retinopathy and neovascular changes and years since diagnosis of diabetes. This cross-sectional study aims to report on the prevalence of glaucoma in diabetic patients in community diabetes centre in Sudan and examine associations with previously reported risk factors.Methods: A cross-sectional study was carried out in Omdurman specialised diabetic healthcare centre in Sudan. A total of 300 patients consented to participation. All patients filled in a survey for both demographics and diabetic disease history then had an assessment for glaucoma by an ophthalmologist. The assessment included examination of the anterior segment, optic nerve assessment and fundus examination using a stereoscopic slit lamp, intraocular pressure (IOP) measurement using tonometry, peripheral anterior chamber configuration and depth assessments using gonioscopy and central visual field assessment using perimetry.Results: Prevalence of open-angle glaucoma diagnosis was 2.8% among diabetic patients who were included in this study. Family history for glaucoma was significantly associated with increased risk of open-angle glaucoma (OR 5.67, 95% CI 1.74-18.45). Retinopathy was also associated with an increased risk of developing the condition (OR 3.1, 95% CI 1.11-8.51). Gender, years since diabetes diagnosis and medications did not have significant associations.Conclusions: Patients with diabetes are at increased risk of developing open-angle glaucoma, but the prevalence among the diabetic population attending community diabetes centre in Sudan remains low. Among different clinical determinants, diabetic retinopathy and genetic determinants may explain the increased risk in the diabetic population.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Jnadi M. Madkhali ◽  
Ammar A. Hakami ◽  
Ali H. Dallak ◽  
Ramzi M. Hakami ◽  
Abdullah A. Yatimi ◽  
...  

Context. Patients with diabetes mellitus (DM) have a poorer quality of life when compared with patients without DM. In fact, one in every five diabetic patients suffers from comorbid depression, which can lead to poor management, poor compliance with treatment, and low quality of life. Therefore, we assessed the prevalence of depression and identified its associated factors among diabetic patients at Jazan Province, KSA. Methods and Materials. A cross-sectional study was conducted among 500 diabetic patients attending a diabetic center in addition to four primary healthcare centers. We used a simple Arabic translation of the Beck Depression Inventory (BDI II) tool to evaluate the depression level among the subjects. We also evaluated the frequencies of certain sociodemographic characteristics and clinical information. Moreover, we performed univariate and multivariate analyses to identify the potential risk factors using adjusted odds ratios (AORs). Results. The prevalence of depression among DM patients was 20.6%. The majority of patients showed no depression (N = 285, 59.4%), one-fifth had mild depression (N = 96, 20.0%), some (N = 55, 11.4%) had moderate depression, and some had severe depression (N = 44, 9.2%). Depression was significantly more prevalent among uneducated patients (N = 27, 31.8%) (X2 = 17.627, P = 0.001) and patients with low monthly income (< 2500 SR/month) (N = 33, 22.8%) (X2 = 9.920, P = 0.019). Hypertension (AOR = 2.531, 95% CI [1.454, 4.406]) and ischemic heart diseases (AOR = 3.892, 95% CI [1.995, 7.593]) were considered as risk factors for depression among diabetic patients. Conclusions. Almost one in every five patients with DM is affected by depression coexisting with cardiovascular diseases. Therefore, screening for psychological problems, proper treatment, and educating patients with diabetes about DM self-management should be routine components of DM care.


2008 ◽  
Vol 20 (9) ◽  
pp. 829-836 ◽  
Author(s):  
Jean-François Cadranel ◽  
Vincent Di Martino ◽  
Guy Lambrey ◽  
Catherine Mourlhon ◽  
Bernard Nalet ◽  
...  

2016 ◽  
Vol 23 (02) ◽  
pp. 138-146
Author(s):  
Shabnam Naveed ◽  
Syed Masroor Ahmed ◽  
Ayesha Nageen ◽  
Zeeshan Ali ◽  
Santosh Kumar ◽  
...  

Objectives: To determine the prevalence and the associated risk factors ofNAFLD in Type 2 diabetic patients. Study Design: Cross sectional study. Setting: Diabeticclinic of Medical Unit 3, JPMC. Methods: It is a cross sectional study. 262 patients wereenrolled between the ages of 18-70 years attending Diabetes Clinic of Medical Unit III, JPMC.Each consenting patient underwent a detailed medical history-taking, physical examination,laboratory assessment and abdominal ultrasonography (US). Fatty liver was diagnosed onabdominal US on the basis of two out of the three criteria: increased hepatic echogenicity,blurring of liver vasculature and deep attenuation of the ultrasonographic signal. In accordancewith the guidelines, subjects diagnosed with NAFLD had to fulfill the following criteria: nohistory of current or past alcohol consumption, other systemic illness known to cause fatty liverdisease; absence of history and clinical, biochemical and US findings consistent with cirrhosis.Body mass index (BMI) was calculated. Blood pressures of greater than 130/90 were takenas hypertensive. LFTs, FBS, HbA1c, Lipid profiles were taken. Results: Out of 262 diabeticpatients 107 (40.8%) of them were found to be having NFALD. Prevalence was found out to behigher in age group of 41-50 years, females, obese & in Pashtoon subjects.It was also moreprevalent in sedentary lifestyle patients and those on oral anti diabetics in contrast to insulintherapy. It was correlating well with US findings when the ALT cut-off value was taken as 30 IUfor males and 19 IU for females compared to standard values of ALT. There was associationwith hypertension, metabolic syndrome and dyslipidemia. Conclusion: Prevalence of NAFLDwas higher in our diabetic patients. Middle age, female gender and obesity were found to bestatistically strong risk factors in our study.


2021 ◽  
Author(s):  
Evariste Ntaganda ◽  
Regine Mugeni ◽  
Emmanuel Harerimana ◽  
Gedeon Ngoga ◽  
Symaque Dusabeyezu ◽  
...  

Abstract Background: Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factors is a crucial pillar for CVD prevention. Design and method: This cross-sectional study included 4284 subjects, mean age 46±16SD, 56.4% females and mean BMI 26.6±3.7 SD. Data were collected through a screening campaign in rural area of Kirehe District, Eastern of Rwanda, with the objective to characterize and examine the prevalence of elevated blood pressure (BP) and other CVD risk factors. An adapted tool from the World Health Organization STEPwise Approach was used for data collection. Elevated BP was defined as ≥140/90 mm/Hg and elevated blood glucose as blood glucose ≥100 mg/dl after a six-hours fast. Results: Of the sampled population, 21.2% (n=910) had an elevated BP at screening; BP was elevated among individuals not previously known to have HTN in 18.7% (n=752). Among individuals with a prior diagnosis of HTN, 62.2% (n=158 of 254) BP was uncontrolled. Age, weight, smoking, alcohol history and waist circumference were associated with BP in both univariate analyses and multivariate analysis. Conclusion: High rates of elevated BP identified through a health screening campaign in this Rwandan district were surprising given the rural characteristics of the district and relatively low population age. These data highlight the need to implement an adequate strategy for the prevention, diagnosis, and control of HTN that includes rural areas of Rwanda as part of a multicomponent strategy for CVD prevention.


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