scholarly journals The scrambling index set of primitive minimally strong digraphs

2016 ◽  
Vol 500 ◽  
pp. 1-14 ◽  
Author(s):  
Yanling Shao ◽  
Yubin Gao
Keyword(s):  
Index Set ◽  
Scrambling Index

Sensitivity Analysis and Selection of Check Index of Signal Intersection Simulation Model Based on VISSIM

2019 ◽  
Vol 2 (5) ◽  
Author(s):  
Mengda Zhang ◽  
Chenjing Zhou ◽  
Tian-tian Zhang ◽  
Yan Han
Keyword(s):  
Sensitivity Analysis ◽  
Simulation Model ◽  
Optimal Process ◽  
Parameter Calibration ◽  
Index Set ◽  
The Core ◽  
Core Module ◽  
Simulation Parameter ◽  
Simulation Parameters ◽  
Selection Of

Selecting check index quantitatively is the core of the calibration of micro traffic simulation parameters at signal intersection. Five indexes in the node (intersection) module of VISSIM were selected as the check index set. Twelve simulation parameters in the core module were selected as the simulation parameters set. Optimal process of parameter calibration was proposed and model of the intersection of Huangcun west street and Xinghua street in Beijing was built in VISSIM to verify it. The sensitivity analysis between each check index and simulation parameter in their own set was conducted respectively. Sensitive parameter sets of different check indices were obtained and compared. The results show that different indexes have different size of set, and average vehicle delay's is maximum, so it's necessary to select index quantitatively. The results can provide references for scientific selection of the check indexes and improve the study efficiency of parameter calibration.

3-VERTEX FULL BALANCE INDEX SET OF GRAPHS

2020 ◽  
Vol 9 (6) ◽  
pp. 3247-3264
Author(s):  
N. C. Devadas ◽  
H. J. Gowtham ◽  
S. D'Souza ◽  
P. G. Bhat
Keyword(s):  
Index Set ◽  
Balance Index

scholarly journals A “Target Class” Screen to Identify Activators of Two-Pore Domain Potassium (K2P) Channels

2020 ◽  
pp. 247255522097612
Author(s):  
David McCoull ◽  
Emma Ococks ◽  
Jonathan M. Large ◽  
David C. Tickle ◽  
Alistair Mathie ◽  
...  
Keyword(s):  
Mammalian Cells ◽  
Point Of View ◽  
Resting Membrane Potential ◽  
Small Molecule Activation ◽  
Target Class ◽  
Index Set ◽  
Diverse Range ◽  
K2p Channels ◽  
Additional Approach ◽  
Pore Domain

Two-pore domain potassium (K2P) channels carry background (or leak) potassium current and play a key role in regulating resting membrane potential and cellular excitability. Accumulating evidence points to a role for K2Ps in human pathophysiologies, most notably in pain and migraine, making them attractive targets for therapeutic intervention. However, there remains a lack of selective pharmacological tools. The aim of this work was to apply a “target class” approach to investigate the K2P superfamily and identify novel activators across all the described subclasses of K2P channels. Target class drug discovery allows for the leveraging of accumulated knowledge and maximizing synergies across a family of targets and serves as an additional approach to standard target-based screening. A common assay platform using baculovirus (BacMam) to transiently express K2P channels in mammalian cells and a thallium flux assay to determine channel activity was developed, allowing the simultaneous screening of multiple targets. Importantly, this system, by allowing precise titration of channel function, allows optimization to facilitate the identification of activators. A representative set of channels (THIK-1, TWIK-1, TREK-2, TASK-3, and TASK-2) were screened against a library of Food and Drug Administration (FDA)-approved compounds and the LifeArc Index Set. Activators were then analyzed in concentration–response format across all channels to assess selectivity. Using the target class approach to investigate the K2P channels has enabled us to determine which of the K2Ps are amenable to small-molecule activation, de-risk multiple channels from a technical point of view, and identify a diverse range of previously undescribed pharmacology.

scholarly journals The scrambling index of symmetric primitive matrices

2010 ◽  
Vol 433 (6) ◽  
pp. 1110-1126 ◽  
Author(s):  
Shexi Chen ◽  
Bolian Liu
Keyword(s):  
Scrambling Index

scholarly journals A discrete Stochastic Korovkin theorem

1991 ◽  
Vol 14 (4) ◽  
pp. 679-682
Author(s):  
George A. Anastassiou
Keyword(s):  
Stochastic Processes ◽  
State Space ◽  
Sufficient Condition ◽  
Korovkin Theorem ◽  
Index Set ◽  
Real State

In this article we give a sufficient condition for the pointwise−−in the first mean Korovkin property onB0(P), the space of stochastic processes with real state space and countable index setΓand bounded first moments.

The Establishment of Exergy Consumption Evaluation Index in Heated Oil Pipeline Transportation

2013 ◽  
Vol 401-403 ◽  
pp. 2143-2146 ◽  
Author(s):  
Qing Lin Cheng ◽  
Zhe Li ◽  
Shuai Shao ◽  
Wei Sun ◽  
Xu Xu Wang
Keyword(s):  
Energy Efficiency ◽  
Energy Consumption ◽  
Evaluation System ◽  
Index Set ◽  
Oil Pipeline ◽  
Heated Oil ◽  
Consumption Index ◽  
Exergy Consumption ◽  
Exergy Transfer ◽  
Set Up

The exergy consumption during the transportation of heated oil includes four items: valid and invalid pressure exergy consumption, valid and invalid heat exergy consumption. These four parts are taken as the same loss in traditional evaluation systems of pipeline energy consumption, which somewhat hinders the further energy-conservation study. So establishing a scientific exergy consumption evaluation system is an important basis work of energy efficiency management. Based on the index system of energy efficiency for pipeline proposed by predecessors, the meaning of energy quality for exergy and the categories of exergy flow, the energy consumption index set of exergy transfer is set up in this article. Moreover, by computing exergy consumption index of exergy transfer for an oil pipeline in Daqing Oilfield, a part of representative indexes are selected by analyzing the obtained data with correlation coefficient method. Finally, the exergy consumption evaluation system is constructed.

Research on Optimal Index Set Based on Consequence-Reverse-Diffusion Method of Yellow River Downstream Embankment

2014 ◽  
Vol 955-959 ◽  
pp. 3020-3025
Author(s):  
Feng Feng ◽  
Hong Tao Jia ◽  
Xiao Ming Rong
Keyword(s):  
Index System ◽  
Influence Factor ◽  
Yellow River ◽  
Influence Factors ◽  
Safety Evaluation ◽  
Diffusion Method ◽  
The Yellow River ◽  
Index Set ◽  
Main Factors ◽  
River Embankment

Constructing a scientific, reasonable, all-encompassing, and representative-strong index system is an important premise and guarantee for the good embankment-safety-evaluation of Yellow River. Therefore, the embankment safety-influencing-factor identification has been raised based on consequence-reverse-diffusion method, which can be used to seek the main factors leading to accidents by reverse-thinking and reverse-diffusion way. The main factors which lead to the embankment accident shall be found out according to the accident form, then spreading to the specific influence-factor. As a result, the author has made a classification and extraction for the identified safety-influence-factors, and constructed the optional index-set and index-system for the Yellow River embankment-safety-evaluation after analyzing the content of the safety-influence-factors, which has laid a solid foundation for further embankment safety assessment for the Yellow River embankment construction.

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