Recent advances and new insights into muscular lymphangiogenesis in health and disease

Life Sciences ◽  
2018 ◽  
Vol 211 ◽  
pp. 261-269 ◽  
Author(s):  
Rui-Cheng Ji
Keyword(s):  
Recent Advances ◽  
Health And Disease

scholarly journals Platelets in Healthy and Disease States: From Biomarkers Discovery to Drug Targets Identification by Proteomics

2020 ◽  
Vol 21 (12) ◽  
pp. 4541 ◽  
Author(s):  
Erica Gianazza ◽  
Maura Brioschi ◽  
Roberta Baetta ◽  
Alice Mallia ◽  
Cristina Banfi ◽  
...  
Keyword(s):  
Drug Targets ◽  
Disease Diagnosis ◽  
Post Translational Modifications ◽  
Disease States ◽  
Recent Advances ◽  
Health And Disease ◽  
Proteome Changes ◽  
Platelet Proteomics ◽  
The Impact ◽  
Platelet Functions

Platelets are a heterogeneous small anucleate blood cell population with a central role both in physiological haemostasis and in pathological states, spanning from thrombosis to inflammation, and cancer. Recent advances in proteomic studies provided additional important information concerning the platelet biology and the response of platelets to several pathophysiological pathways. Platelets circulate systemically and can be easily isolated from human samples, making proteomic application very interesting for characterizing the complexity of platelet functions in health and disease as well as for identifying and quantifying potential platelet proteins as biomarkers and novel antiplatelet therapeutic targets. To date, the highly dynamic protein content of platelets has been studied in resting and activated platelets, and several subproteomes have been characterized including platelet-derived microparticles, platelet granules, platelet releasates, platelet membrane proteins, and specific platelet post-translational modifications. In this review, a critical overview is provided on principal platelet proteomic studies focused on platelet biology from signaling to granules content, platelet proteome changes in several diseases, and the impact of drugs on platelet functions. Moreover, recent advances in quantitative platelet proteomics are discussed, emphasizing the importance of targeted quantification methods for more precise, robust and accurate quantification of selected proteins, which might be used as biomarkers for disease diagnosis, prognosis and therapy, and their strong clinical impact in the near future.

scholarly journals Has knowledge of the vaginal microbiome altered approaches to health and disease?

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 460 ◽  
Author(s):  
Gregor Reid
Keyword(s):  
Molecular Characterization ◽  
Vaginal Microbiota ◽  
Vaginal Microbiome ◽  
Recent Advances ◽  
Microbiome Research ◽  
Health And Disease ◽  
Vaginal Health

Sixteen years ago, when we published the first molecular characterization of the vaginal microbiota, little did we know the vast numbers of species that would be detected in this niche. As exciting as these discoveries have been, what have they and more recent advances contributed to how vaginal health and disease are managed? This review provides a brief discussion of the potential, but so far limited, applications that have arisen from microbiome research. Calls for innovation have been made before but to little avail.

scholarly journals Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function

2021 ◽  
Vol 11 (5) ◽  
pp. 438
Author(s):  
William J. Duddy ◽  
Stephanie Duguez
Keyword(s):  
Neuromuscular Disease ◽  
Molecular Function ◽  
Recent Advances ◽  
Muscle Biology ◽  
Health And Disease

The field of neuromuscular research has seen considerable recent advances in the molecular and cellular understanding of muscle biology, and the treatment of neuromuscular disease [...]

The 2012 AANS Presidential Address

2012 ◽  
Vol 117 (6) ◽  
pp. 983-996 ◽  
Author(s):  
Paul C. McCormick
Keyword(s):  
Nervous System ◽  
Annual Meeting ◽  
American Association ◽  
Presidential Address ◽  
Science Practice ◽  
Recent Advances ◽  
Health And Disease ◽  
Human Nervous System

The theme of the 80th Annual Meeting of the American Association of Neurological Surgeons and the title of this presidential address, “We are neurosurgery,” is a simple 3-word affirmation of who neurosurgeons are, what they have achieved, and how much there is yet to accomplish. Recent advances in neurobiology and the clinical neurosciences have brought an unprecedented understanding of the human nervous system in both health and disease. As a specialty, neurosurgery has translated knowledge, expanded techniques, and incorporated technology to exponentially expand the science and scope of neurosurgical practice. However, the rapidly advancing, divergently evolving growth of neurosurgery has had profound effects on all aspects of neurosurgery. In this address, the author examines the contemporary meaning of the annual meeting's theme as it relates to the science, practice, specialty, and profession of neurosurgery, as well as the neurosurgeon. In doing so, the author reveals his interpretation of “We are neurosurgery,” which he hopes will have an effect on others.

Recent advances in the role of interleukin-6 in health and disease

2020 ◽  
Vol 52 ◽  
pp. 47-51 ◽  
Author(s):  
Willem T Peppler ◽  
Logan K Townsend ◽  
David C Wright
Keyword(s):  
Interleukin 6 ◽  
Recent Advances ◽  
Health And Disease

scholarly journals Special Issue: MicroRNA Regulation in Health and Disease

Genes ◽  
2019 ◽  
Vol 10 (6) ◽  
pp. 457 ◽  
Author(s):  
Subbaya Subramanian ◽  
Clifford J. Steer
Keyword(s):  
Molecular Biology ◽  
Special Issue ◽  
Microrna Regulation ◽  
Recent Advances ◽  
Non Coding Rna ◽  
Health And Disease

Our understanding of non-coding RNA has significantly changed based on recent advances in genomics and molecular biology, and their role is recognized to include far more than a link between the sequence of DNA and synthesized proteins [...]

Recent Advances in the Structural Study of Functional Chondroitin Sulfate and Dermatan Sulfate in Health and Disease

2008 ◽  
Vol 49 (3-4) ◽  
pp. 133-139 ◽  
Author(s):  
Christina Malavaki ◽  
Shuji Mizumoto ◽  
Nikos Karamanos ◽  
Kazuyuki Sugahara
Keyword(s):  
Chondroitin Sulfate ◽  
Structural Study ◽  
Dermatan Sulfate ◽  
Recent Advances ◽  
Health And Disease

scholarly journals Recent Advances in Applied Microbiology: Editorial

2020 ◽  
Vol 8 (9) ◽  
pp. 1364
Author(s):  
Letícia M. Estevinho ◽  
Patrícia Combarros-Fuertes ◽  
Vanessa Branco Paula
Keyword(s):  
Economic Value ◽  
Alcoholic Beverages ◽  
Original Research ◽  
Research Papers ◽  
Recent Advances ◽  
Wide Range ◽  
Applied Microbiology ◽  
Health Promoting ◽  
Health And Disease ◽  
By Products

The importance of microbiology has grown exponentially since the development of genomics, transcriptomics, and proteomics, making it possible to clarify microbial biogeochemical processes and their interactions with macroorganisms in both health and disease. Particular attention is being payed to applied microbiology, a discipline that deals with the application of microorganisms to specific endeavors, whose economic value is expected to exceed USD 675.2 billion by 2024. In the Special Issue “Recent Advances in Applied Microbiology”, twenty-four papers were published (four reviews and twenty original research papers), covering a wide range of subjects within applied microbiology, including: microbial pathogenesis, the health-promoting properties of microorganisms and their by-products, food conservation, the production of alcoholic beverages, bioremediation and the application of microbiology to several industrial processes.

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