A rapid, solvent-free microwave-assisted method has been developed for the synthesis of novel furo quinolines. The title compounds were achieved by the reaction between corresponding 2-hydroxy-3-formyl-quinolines (1a–1c) with chloroacetamide, ethylchloroacetate, and phenacylbromide in specially designed microwave (MW) oven for organic synthesis in unsealed borosil vessel in presence of potassium carbonate. In this method, isolation is accomplished by just treating the reaction mixture with water, and products were obtained in high yield. Hence, this method was found to be very effective and ecofriendly. The structure of the newly synthesized compounds has been evaluated on the basis of analytical, IR, 1H NMR, and mass spectral data.Key words: furoquinoline, microwave irradiation, potassium carbonate, solvent-free conditions.
Cinnamomum camphora fruit peel as a source of essential oil extracted using the solvent-free microwave-assisted method compared with conventional hydrodistillation
