Role of latency period in viral infection: A pest control model

2007 ◽  
Vol 210 (2) ◽  
pp. 619-646 ◽  
Author(s):  
S. Ghosh ◽  
S. Bhattacharyya ◽  
D.K. Bhattacharya
2013 ◽  
Vol 2013 ◽  
pp. 1-12
Author(s):  
Samit Bhattacharyya ◽  
Suma Ghosh

We study the role of predation dynamics in oscillation of pest population in insect ecology. A two-dimensional pest control model (under the use of insecticides) with time delay in predation is considered in this paper. By the Hopf bifurcation theory, we prove the existence of the stable oscillation of the system. We also consider the economic viability of the control process. First we improve the Pontryagin maximum principle (PMP) where the delay in the system is sufficiently small and control function is linear, and then we apply the improved version of PMP to perform the optimal analysis of the pest control model as a special case.


2007 ◽  
Vol 69 (8) ◽  
pp. 2649-2691 ◽  
Author(s):  
S. Ghosh ◽  
S. Bhattacharyya ◽  
D. K. Bhattacharya

Author(s):  
Rabih Halwani ◽  
Mehrnoosh Doroudchi ◽  
Mohamed El-Far ◽  
Andre Tanel ◽  
Yu Shi ◽  
...  

Author(s):  
Ayman A. Arafa ◽  
Soliman A.A. Hamdallah ◽  
Sanyi Tang ◽  
Yong Xu ◽  
Gamal M. Mahmoud

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1720
Author(s):  
Kuo-Chieh Liao ◽  
Mariano A. Garcia-Blanco

The importance of transcriptional regulation of host genes in innate immunity against viral infection has been widely recognized. More recently, post-transcriptional regulatory mechanisms have gained appreciation as an additional and important layer of regulation to fine-tune host immune responses. Here, we review the functional significance of alternative splicing in innate immune responses to viral infection. We describe how several central components of the Type I and III interferon pathways encode spliced isoforms to regulate IFN activation and function. Additionally, the functional roles of splicing factors and modulators in antiviral immunity are discussed. Lastly, we discuss how cell death pathways are regulated by alternative splicing as well as the potential role of this regulation on host immunity and viral infection. Altogether, these studies highlight the importance of RNA splicing in regulating host–virus interactions and suggest a role in downregulating antiviral innate immunity; this may be critical to prevent pathological inflammation.


2021 ◽  
Vol 42 (1) ◽  
pp. 77-85
Author(s):  
Meghana Muthuvattur Pallath ◽  
Ashok Kumar Ahirwar ◽  
Satyendra Chandra Tripathi ◽  
Priyanka Asia ◽  
Apurva Sakarde ◽  
...  

Abstract COVID-19 has resulted in an ongoing global pandemic, which spread largely among people who have had close contact with the infected person. The immunopathology of the SARS-CoV-2 virus includes the production of an excess amount of pro-inflammatory cytokines “a cytokine-storm”. The respiratory system (main), cardiovascular system and the gastrointestinal tract are the most affected body systems during viral infection. It has been found that most of the patients who require admission to hospital are elderly or have chronic underlying diseases. Higher cases of malnutrition and co-morbidities like diabetes mellitus and cardiovascular diseases are reported in elderly patients due to which, the immune system weakens and hence, the response to the virus is diminished in magnitude. A deficiency of micronutrients results in impaired immune responses leading to improper secretion of cytokines, alterations in secretory antibody response and antibody affinity which increases susceptibility to viral infection. The deficiency of various micronutrients in COVID-19 patient can be treated by appropriate nutritional supplements, prescribed after evaluating the patients’ nutritional status. Here we aim to highlight the role of a few particular nutrients namely Vitamin D, Vitamin C, Omega-3 fatty acids, Zinc and Magnesium along with the synergistic roles they play in enhancing immunity and thus, maintaining homeostasis.


2021 ◽  
Author(s):  
Mina Zare ◽  
Mika Sillanpää ◽  
Seeram Ramakrishna

The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) caused the pandemic COVID-19 disease since December 2019 highlights the importance of developing efficient antiviral strategies to prevent and treat viral infection. Virus...


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