Effect of solvents on electrospun fibers and the biological application of different hydrophilic electrospun mats

2021 ◽  
pp. 103093
Author(s):  
Wen Shen ◽  
Fen Ao ◽  
Xuemei Ge ◽  
Yuanlan Ning ◽  
Lan Wang ◽  
...  
Keyword(s):  
Electrospun Fibers ◽  
Biological Application ◽  
Effect Of Solvents

Scanning Electron Microscopic Study of the Cell Surface

1969 ◽  
Vol 27 ◽  
pp. 36-37 ◽  
Author(s):  
Toichiro Kuwabara
Keyword(s):  
Tissue Fluid ◽  
Biological Application ◽  
Biological Structure ◽  
Electron Microscopic ◽  
Surface Appearance ◽  
Minute Amount ◽  
Scanning Electron Microscopic Study ◽  
Scanning Electron Microscopic ◽  
True Structure ◽  
Scanning Electron

Although scanning electron microscopy has a great potential in biological application, there are certain limitations in visualization of the biological structure. Satisfactory techniques to demonstrate natural surfaces of the tissue and the cell have been reported by several investigators. However, it is commonly found that the surface cell membrane is covered with a minute amount of mucin, secretory substance or tissue fluid as physiological, pathological or artefactual condition. These substances give a false surface appearance, especially when the tissue is fixed with strong fixatives. It seems important to remove these coating substances from the surface of the cell for demonstration of the true structure.

A Peptoid with Extended Shape in Water

2019 ◽  
Author(s):  
Jumpei Morimoto ◽  
Yasuhiro Fukuda ◽  
Takumu Watanabe ◽  
Daisuke Kuroda ◽  
Kouhei Tsumoto ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
Dimensional Space ◽  
Three Dimensional ◽  
Biomolecular Recognition ◽  
Biological Application ◽  
New Class ◽  
Proteolytic Resistance ◽  
Pharmacokinetic Properties ◽  
Optically Pure ◽  
Three Dimensional Space

<div> <div> <div> <p>“Peptoids” was proposed, over decades ago, as a term describing analogs of peptides that exhibit better physicochemical and pharmacokinetic properties than peptides. Oligo-(N-substituted glycines) (oligo-NSG) was previously proposed as a peptoid due to its high proteolytic resistance and membrane permeability. However, oligo-NSG is conformationally flexible and is difficult to achieve a defined shape in water. This conformational flexibility is severely limiting biological application of oligo-NSG. Here, we propose oligo-(N-substituted alanines) (oligo-NSA) as a new peptoid that forms a defined shape in water. A synthetic method established in this study enabled the first isolation and conformational study of optically pure oligo-NSA. Computational simulations, crystallographic studies and spectroscopic analysis demonstrated the well-defined extended shape of oligo-NSA realized by backbone steric effects. The new class of peptoid achieves the constrained conformation without any assistance of N-substituents and serves as an ideal scaffold for displaying functional groups in well-defined three-dimensional space, which leads to effective biomolecular recognition. </p> </div> </div> </div>

Non-biological application of DNA molecules

Biomics ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 344-377
Author(s):  
A.R. Sakhabutdinova ◽  
K.I. Mikhailenko ◽  
R.R. Garafutdinov ◽  
O.Yu. Kiryanova ◽  
M.A. Sagitova ◽  
...  
Keyword(s):  
Biological Application ◽  
Dna Molecules

Electrospun Fibers for Composites Applications

2014 ◽  
Author(s):  
Joshua A. Orlicki ◽  
Joshua Steele ◽  
Andre A. Williams ◽  
George R. Martin ◽  
Eugene Napadensky ◽  
...  
Keyword(s):  
Electrospun Fibers

Medicinal and Biological Significance of Phenoxazine Derivatives

2020 ◽  
Vol 20 ◽  
Author(s):  
Jaya Dwivedi ◽  
Neetu Yaduvanshi ◽  
Shruti Shukla ◽  
Sonika Jain
Keyword(s):  
Drug Resistance ◽  
Biological Significance ◽  
Biological Application ◽  
Pharmacological Activities ◽  
Resistance Reversal ◽  
Anti Inflammatory ◽  
Pharmacological Application

: Since 1887, phenoxazine derivatives have attracted attention of chemist due to its versatile utility, industrially and pharmacologically. Literature is found abundant with various pharmacological activities of phenoxazine derivatives like antitumor, anticancer, antifungal, antibacterial, anti-inflammatory, anti-diabetic, anti-viral, anti-malarial, antidepressant, analgesic and many other drug resistance reversal activities. This review covers detailed over-view on pharmacological application of phenoxazine nucleus, its chemistry and reactivity and also illustrating the incorporation of different group at different positions enhancing its biological application, besides some synthetic procedures.

Electrospun Fibers for Dental and Craniofacial Applications

2014 ◽  
Vol 9 (3) ◽  
pp. 187-195 ◽  
Author(s):  
Guo Li ◽  
Tong Zhang ◽  
Meng Li ◽  
Na Fu ◽  
Yao Fu ◽  
...  
Keyword(s):  
Electrospun Fibers

A Fluidic Motherboard for Multiplexed Simultaneous and Modular Detection in Microfluidic Systems for Biological Application

2010 ◽  
Vol 2 (4) ◽  
pp. 227-238 ◽  
Author(s):  
Gerardo Perozziello ◽  
Giuseppina Simone ◽  
Patrizio Candeloro ◽  
Francesco Gentile ◽  
Natalia Malara ◽  
...  
Keyword(s):  
Biological Application ◽  
Microfluidic Systems

scholarly journals Focused Patterning of Electrospun Nanofibers Using a Dielectric Guide Structure

Polymers ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1505
Author(s):  
Byeongjun Lee ◽  
Younghyeon Song ◽  
Chan Park ◽  
Jungmin Kim ◽  
Jeongbeom Kang ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Finite Elements ◽  
Electric Field ◽  
Electrospun Nanofibers ◽  
Electrospun Fibers ◽  
Continuous Line ◽  
Key Factors ◽  
Key Technology ◽  
Vertical Electric Field ◽  
Dielectric Guide

The patterning of electrospun fibers is a key technology applicable to various fields. This study reports a novel focused patterning method for electrospun nanofibers that uses a cylindrical dielectric guide. The finite elements method (FEM) was used to analyze the electric field focusing phenomenon and ground its explanation in established theory. The horizontal and vertical electric field strengths in the simulation are shown to be key factors in determining the spatial distribution of nanofibers. The experimental results demonstrate a relationship between the size of the cylindrical dielectric guide and that of the electrospun area accumulated in the collector. By concentrating the electric field, we were able to fabricate a pattern of less than 6 mm. The demonstration of continuous line and square patterning shows that the electrospun area can be well controlled. This novel patterning method can be used in a variety of applications, such as sensors, biomedical devices, batteries, and composites.

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