Toxic-metabolic encephalopathy in adults: Critical discussion and pragmatical diagnostic approach

2022 ◽  
Author(s):  
L. Le Guennec ◽  
C. Marois ◽  
S. Demeret ◽  
E.F.M. Wijdicks ◽  
N. Weiss
Keyword(s):  
Critical Discussion ◽  
Diagnostic Approach ◽  
Metabolic Encephalopathy

Fault Detection and Identification by Gas Path Analysis Approach in Heavy Duty Gas Turbine

2006 ◽  
Author(s):  
Stefania Della Gatta ◽  
Paolo Adami
Keyword(s):  
Path Analysis ◽  
Gas Turbine ◽  
Diagnostic System ◽  
Theoretical Background ◽  
Critical Discussion ◽  
Diagnostic Approach ◽  
Health State ◽  
Heavy Duty ◽  
Fault Detection And Identification ◽  
Heavy Duty Gas Turbine

The possibility to get information about gas turbine “health” state is largely based on availability and reliability of operational data and on-line acquisition systems. However, further instruments are needed in order to deduce useful information in maintenance scheduling from actually measured data. In Gas Path Analysis approaches, a model to simulate the engine behavior is required. Furthermore, in order to individuate, locate and evaluate faulty conditions, a diagnostic approach needs to be developed and introduced. This paper presents a critical discussion of the problem to highlight the main requirements of a diagnostic approach. Furthermore, some procedures to verify the ability of a diagnostic tool can be obtained directly from the theoretical background of GPA. To demonstrate how these procedures work, an application case has been examined. An engine model has been specifically developed for the monitored heavy-duty gas turbine. It allows to calculate thermodynamics data and to identify performance parameters through a mathematical modeling process. The suitability of this model to be introduced in a diagnostic system has been investigated. An exhaustive description of the procedures and discussion of results are reported.

Experiences With and Lessons Learned From Developing, Implementing, and Evaluating a Support Program for Older Hearing Aid Users and Their Communication Partners in the Hearing Aid Dispensing Setting

2020 ◽  
Vol 29 (3S) ◽  
pp. 638-647 ◽  
Author(s):  
Janine F. J. Meijerink ◽  
Marieke Pronk ◽  
Sophia E. Kramer
Keyword(s):  
Large Scale ◽  
Hearing Aid ◽  
Critical Discussion ◽  
Lessons Learned ◽  
Research Note ◽  
Support Program ◽  
Large Sample Size ◽  
Long Term Effects ◽  
Communication Program ◽  
Communication Partners

Purpose The SUpport PRogram (SUPR) study was carried out in the context of a private academic partnership and is the first study to evaluate the long-term effects of a communication program (SUPR) for older hearing aid users and their communication partners on a large scale in a hearing aid dispensing setting. The purpose of this research note is to reflect on the lessons that we learned during the different development, implementation, and evaluation phases of the SUPR project. Procedure This research note describes the procedures that were followed during the different phases of the SUPR project and provides a critical discussion to describe the strengths and weaknesses of the approach taken. Conclusion This research note might provide researchers and intervention developers with useful insights as to how aural rehabilitation interventions, such as the SUPR, can be developed by incorporating the needs of the different stakeholders, evaluated by using a robust research design (including a large sample size and a longer term follow-up assessment), and implemented widely by collaborating with a private partner (hearing aid dispensing practice chain).

Marx and the “law of value”: Critical appraisal on the occasion of his 200th birth anniversary

2018 ◽  
pp. 27-49 ◽  
Author(s):  
H. D. Kurz
Keyword(s):  
Karl Marx ◽  
Critical Appraisal ◽  
Critical Discussion ◽  
Use Value ◽  
Transformation Problem ◽  
The Common ◽  
The Law

The paper celebrates Karl Marx’ 200th birthday in terms of a critical discussion of the “law of value” and the idea that “abstract labour”, and not any use value, is the common third of any two commodities that exchange for one another in a given proportion. It is argued that this view is difficult to sustain. It is also the source of the wretched and unnecessary “transformation problem”. Ironically, as Piero Sraffa has shown, prices of production and the general rate of profits are fully determined in terms of the same set of data from which Marx started his analysis.

The Accuracy of ACR TI-RADS Classification of Neck Ultrasound as a First-Line Diagnostic Approach for Thyroid Neoplasms in Pediatric Patients: A Retrospective Study

2018 ◽  
Vol 5 (1) ◽  
pp. 13-23
Author(s):  
Nikolai S. Grachev ◽  
Elena V. Feoktistova ◽  
Igor N. Vorozhtsov ◽  
Natalia V. Babaskina ◽  
Ekaterina Yu. Iaremenko ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Predictive Value ◽  
Thyroid Nodules ◽  
Pediatric Patients ◽  
Thyroid Neoplasms ◽  
Diagnostic Methods ◽  
Diagnostic Approach ◽  
First Line ◽  
Neck Ultrasound

Background.Ultrasound (US)-guided fine-needle aspiration biopsy (FNAB) is the gold standard in diagnosing the pathological nature of undetermined thyroid nodules. However, in some instances limitations and shortcomings arise, making it insufficient for determining a specific diagnosis.Objective.Our aim was to evaluate the effectiveness of ACR TI-RADS classification of neck ultrasound as a first-line diagnostic approach for thyroid neoplasms in pediatric patients.Methods.A retrospective analysis was made of FNA and US protocols in 70 patients who underwent the examination and treatment at Dmitry Rogachev National Research Center between January 2012 and August 2017. In the retrospective series 70% (49/70) of patients undergone FNA and 43% (30/70) of them undergone repeated FNA. All US protocols were interpreted according to ACR TI-RADS system by the two independent experts. The clinical judgment was assessed using the concordance test and the reliability of preoperative diagnostic methods was analized.Results.According to histologic examination protocols, benign nodules reported greater multimorbidity 29% (20/70), compared with thyroid cancer 17% (12/70), complicating FNA procedure. A statistically significant predictor of thyroid cancer with a tumor size ACR TI-RADS showed a significant advantage of ACR TI-RADS due to higher sensitivity (97.6 vs 60%), specificity (78.6 vs 53.8%), positive predictive value (87.2 vs 71.4%), and negative predictive value (95.7 vs 41.2%). Concordance on the interpreted US protocols according to ACR TI-RADS classification between two experts was high, excluding accidental coincidence.Conclusion.The data support the feasibility of US corresponding to the ACR TI-RADS classification as a first-line diagnostic approach for thyroid neoplasm reducing the number of unnecessary biopsies for thyroid nodules.

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