scholarly journals L1 cell adhesion molecule promotes resistance to alcohol-induced silencing of growth cone responses to guidance cues

Neuroscience ◽  
2011 ◽  
Vol 180 ◽  
pp. 30-40 ◽  
Author(s):  
B. Sepulveda ◽  
I. Carcea ◽  
B. Zhao ◽  
S.R.J. Salton ◽  
D.L. Benson
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Growth Cone ◽  
Cell Adhesion Molecule ◽  
Guidance Cues ◽  
L1 Cell Adhesion Molecule

scholarly journals Semaphorin3D Regulates Axon Axon Interactions by Modulating Levels of L1 Cell Adhesion Molecule

2007 ◽  
Vol 27 (36) ◽  
pp. 9653-9663 ◽  
Author(s):  
M. A. Wolman ◽  
A. M. Regnery ◽  
T. Becker ◽  
C. G. Becker ◽  
M. C. Halloran
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
L1 Cell Adhesion Molecule

scholarly journals Oriented, Multimeric Biointerfaces of the L1 Cell Adhesion Molecule: An Approach to Enhance Neuronal and Neural Stem Cell Functions on 2-D and 3-D Polymer Substrates

2012 ◽  
Vol 7 (1) ◽  
pp. 22 ◽  
Author(s):  
Jocie F. Cherry ◽  
Aaron L. Carlson ◽  
Farah L. Benarba ◽  
Sven D. Sommerfeld ◽  
Devendra Verma ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Adhesion ◽  
Neural Stem Cell ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Polymer Substrates ◽  
Cell Functions ◽  
L1 Cell Adhesion Molecule

scholarly journals PD2-2-3: Prognostic significance of L1 cell adhesion molecule (CAM) expression in pulmonary neuroendocrine tumors

2007 ◽  
Vol 2 (8) ◽  
pp. S440
Author(s):  
Hyo Song Kim ◽  
Keunchil Park ◽  
Hyun Jung Jun ◽  
Seong Yoon Yi ◽  
Joungho Han ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Neuroendocrine Tumors ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Prognostic Significance ◽  
L1 Cell Adhesion Molecule

Inhibition of cell proliferation, adhesion, and invasion with an anti-L1-cell adhesion molecule monoclonal antibody in an in vitro endometriosis model

2010 ◽  
Vol 94 (3) ◽  
pp. 1102-1104 ◽  
Author(s):  
Admir Agic ◽  
Ursula von Wussow ◽  
Anna Starzinski-Powitz ◽  
Klaus Diedrich ◽  
Peter Altevogt ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Cell Proliferation ◽  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
L1 Cell Adhesion Molecule ◽  
Adhesion And Invasion

scholarly journals The Diagnostic Value of Serum L1CAM in Patients With Colorectal Cancer

2020 ◽  
Vol 19 ◽  
pp. 153303382092097
Author(s):  
Ling-Yu Chu ◽  
Dong-Ming Guo ◽  
Jun-Tian Chen ◽  
Wang-Kai Fang ◽  
Jian-Jun Xie ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Adhesion ◽  
Confidence Interval ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Operating Characteristic ◽  
Early Stage ◽  
Diagnostic Value ◽  
L1 Cell Adhesion Molecule ◽  
Normal Controls

Objective: Colorectal cancer is one of the most important malignant cancer in the world with high incidence and mortality. Some studies have found that the expression of low serum L1 cell adhesion molecule is associated with poor prognosis in some malignancies. It is suggested that L1 cell adhesion molecule is a candidate serum marker for certain tumors. However, the relationship between serum L1 cell adhesion molecule and colorectal cancer, especially about the diagnostic value, is rarely reported. Therefore, this study aimed to evaluate the diagnostic potential of serum L1 cell adhesion molecule in patients with colorectal cancer. Methods: Enzyme-linked immunosorbent assay was carried out to detect L1 cell adhesion molecule level in sera of 229 patients with colorectal cancer and 145 normal controls. Receiver operating characteristic curves were employed to calculate the accuracy of diagnosis. Results: The levels of serum L1 cell adhesion molecule in the colorectal cancer group were significantly lower than that in normal controls ( P < .05). In the normal group, the area under the receiver operating characteristic curve (area under the curve) of all colorectal cancer was 0.781 (95% confidence interval: 0.734-0.828) and early-stage colorectal cancer was 0.764 (95% confidence interval: 0.705-0.823). With optimized cutoff of 17.760 ng/mL, L1 cell adhesion molecule showed certain diagnostic value with specificity of 90.3% and sensitivities of 43.2% and 36.2% in colorectal cancer and early-stage colorectal cancer, respectively. Clinical data analysis showed that the levels of L1 cell adhesion molecule were significantly correlated with gender ( P < .05) and early and late stages ( P < .05). Furthermore, when compared with carcinoembryonic antigen, serum L1 cell adhesion molecule had significantly improved diagnostic accuracy for both colorectal cancer and early-stage colorectal cancer. Conclusions: Our study demonstrated that serum L1 cell adhesion molecule might be served as a potential biomarker for the diagnosis of colorectal cancer.

Regulation of the L1 Cell Adhesion Molecule by Thyroid Hormone in the Developing Brain

2000 ◽  
Vol 16 (4) ◽  
pp. 499-514 ◽  
Author(s):  
Manuel Alvarez-Dolado ◽  
Ana Cuadrado ◽  
Cristina Navarro-Yubero ◽  
Peter Sonderegger ◽  
Andrew J. Furley ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Thyroid Hormone ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Developing Brain ◽  
L1 Cell Adhesion Molecule
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