Impact of body mass index and waist circumference on the cardiovascular risk and all-cause death in a general population: Data from the PAMELA study

CONTEXT AND OBJECTIVE: Studies have demonstrated that metabolic complications from child obesity, although silent, increase the risk of development of cardiovascular diseases in adulthood. The present paper sought to describe the prevalence of overweight/obesity and analyze the possible relationship between obesity and other cardiovascular risk factors among children and adolescents. DESIGN AND SETTING: Cross-sectional study, conducted in a university. METHODS: The study included 564 children and adolescents, aged 8 to 17 years. Body mass index and waist circumference were used to evaluate obesity. Other cardiovascular risk factors were evaluated, like systolic and diastolic blood pressure, glycemia, triglycerides and total cholesterol. Descriptive analysis was used for sample characterization, the chi-square test for categorical variables and Pearson's linear correlation for evaluating the relationship between obesity indicators and other cardiovascular risk factors. RESULTS: High prevalence of overweight/obesity was found among the schoolchildren (25.3% among the boys and 25.6% among the girls), along with abdominal obesity (19.0%). The overweight/obese schoolchildren presented higher percentages for the pressure and biochemical indicators, compared with underweight and normal-weight schoolchildren. Body mass index and waist circumference showed a weak correlation with the variables of age and systolic and diastolic blood pressure (P < 0.001), but there was no correlation between these obesity indices and biochemical variables. CONCLUSION: The high prevalence of overweight/obesity and its relationship with other cardiovascular risk factors demonstrate that it is necessary to develop intervention and prevention strategies from childhood onwards, in order to avoid development of chronic-degenerative diseases in adulthood.

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P6232Exploring the bottom of J-shaped curve association between serum uric acid and cardiovascular risks: description using a large Japanese general population

European Heart Journal ◽

10.1093/eurheartj/ehz746.0834 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

S Kawasoe ◽

T Kubozono ◽

S Ojima ◽

H Miyahara ◽

S Maenohara ◽

...

Keyword(s):

Risk Factors ◽

Body Mass Index ◽

Uric Acid ◽

Cardiovascular Risk ◽

General Population ◽

Cardiovascular Risk Factors ◽

Serum Uric Acid ◽

Body Mass ◽

Cardiovascular Risks ◽

Japanese General Population

Abstract Background The J-shaped association between serum uric acid (SUA) and cardiovascular risks is known. However, the bottom of the J-shaped curve has not been elucidated because of the lack of epidemiological knowledge about hypouricemia. Purpose To explore the SUA levels related to the most preferable cardiovascular risks using data from a Japanese general population. Methods Data from 246,923 individuals (111,117 men and 135,806 women) who underwent routine health checkups between January 2001 and December 2015 were analyzed. The participants were divided into quartiles according to their SUA levels, and patients with hypouricemia (SUA level <2.0 mg/dL) were subdivided into two groups according to their distributions. We compared their characteristics, including their cardiovascular risks. Results The prevalence of hypouricemia was 0.46% overall, 0.21% for men, and 0.66% for women (P<0.001). The subjects with hypouricemia were divided into two groups according to SUA level: a lower hypouricemia group (0.4–1.1 mg/dL, which included a peak at 0.7–0.8 mg/dL) and a higher hypouricemia group (1.4–2.0 mg/dL). The two groups exhibited significanly different characteristics in several variables: body mass index and triglyceride in men, and age, body mass index, triglyceride, low-density lipoprotein cholesterol, and renal function in women. Furthermore, several cardiovascular risk factors showed the most preferable values in subjects with SUA 1.4–2.0 mg/dL (Figure). Conclusions There were two independent distributions in subjects with SUA ≤2.0 mg/dL. The individuals with SUA 1.4–2.0 mg/dL exhibited the most preferable values for several cardiovascular risk factors, suggesting an association with the bottom of the J-shaped curve between SUA and cardiovascular risks.

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Urinary triclosan concentrations are inversely associated with body mass index and waist circumference in the US general population: Experience in NHANES 2003–2010

International Journal of Hygiene and Environmental Health ◽

10.1016/j.ijheh.2015.03.004 ◽

2015 ◽

Vol 218 (4) ◽

pp. 401-406 ◽

Cited By ~ 36

Author(s):

Shengxu Li ◽

Jinying Zhao ◽

Guangdi Wang ◽

Yun Zhu ◽

Felicia Rabito ◽

...

Keyword(s):

Body Mass Index ◽

Waist Circumference ◽

General Population ◽

Body Mass ◽

The Us

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The Impacts of Lifestyle Modification Education towards Cardiovascular Risk Profile

Indonesian Journal of Clinical Pharmacy ◽

10.15416/ijcp.2018.7.3.154 ◽

2018 ◽

Vol 7 (3) ◽

pp. 154

Author(s):

Fonny Cokro ◽

Abdul Rahem ◽

Lisa Aditama ◽

Franciscus C. Kristianto

Keyword(s):

Body Mass Index ◽

Cardiovascular Risk ◽

Waist Circumference ◽

Body Mass ◽

Study Design ◽

Lifestyle Modification ◽

Risk Profile ◽

Cardiovascular Risk Profile ◽

Face To Face

Obesity is one of the risk factors of cardiovascular disease. The prevalence of obesity in Indonesia has increased in the last few years, therefore some efforts to reduce the risk is needed. In the current study, efforts are given through 3-week lifestyle modification education, with 3-month total of follow-up (from March to June 2014) and then the impacts on cardiovascular risk profile were observed and seen on 24 sedentary male workers in University of Surabaya with obese II. This study used before-after study design in order to see the impacts of the 3-week lifestyle modification education towards change of knowledge, dietary behavior, body mass index (BMI), waist circumference, and cardiovascular risk profile through various educational methods (face-to-face session, given recorder of face-to-face session, and combination of both methods). Statistical analysis was performed using Wilcoxon signed test. Result showed an increasing knowledge in face-to-face group (p=0.046). However, there were no significant changes in other variables (dietary behavior based on healthy diet indicator (HDI), BMI, waist circumference, and also cardiovascular risk profile) in all groups between before and after education intervention (p>0.05). In conclusion, lifestyle modification education given for 3 weeks did not reduce the cardiovascular risk profile on sedentary male workers with obese II. Longer term intervention and multicomponent program including behavior therapy may be needed to succeed lifestyle changes and reduce cardiovascular risk.Keywords: Behaviour, cardiovascular risk, education, knowledge, lifestyle modification Pengaruh Edukasi Gaya Hidup terhadap Perubahan Risiko Penyakit KardiovaskularAbstrakObesitas merupakan salah satu faktor risiko penyakit kardiovaskular. Prevalensi obesitas di Indonesia mengalami peningkatan beberapa tahun terakhir, sehingga diperlukan upaya untuk menguranginya. Pada penelitian ini, upaya dilakukan melalui pemberian edukasi gaya hidup yang dilakukan selama 3 minggu, dengan total follow-up sampai dengan 3 bulan dari bulan Maret hingga Juni 2014, kemudian dilihat dan diamati ada atau tidaknya penurunan risiko penyakit kardiovaskular pada 24 orang karyawan pria obese II di Universitas Surabaya. Penelitian ini memiliki rancangan before-after study design untuk menguji pengaruh edukasi gaya hidup yang diberikan selama 3 minggu terhadap variabel pengetahuan, perubahan perilaku, body mass index (BMI), lingkar perut, dan risiko penyakit kardiovaskular melalui berbagai metode pemberian edukasi (tatap muka, rekaman/recorder, dan kombinasi). Analisis dengan Wilcoxon signed test menunjukkan bahwa terdapat peningkatan pengetahuan hanya pada subgrup tatap muka (p=0,046). Tidak terdapat perubahan yang signifikan terhadap variabel lainnya (perubahan perilaku berdasarkan healthy diet indicator (HDI), BMI dan lingkar perut, serta risiko penyakit kardiovaskular) pada semua subgrup antara sebelum dan sesudah edukasi (p>0,05). Edukasi gaya hidup yang diberikan selama tiga minggu tidak memberikan penurunan risiko penyakit kardiovaskular pada karyawan pria obese II. Dibutuhkan intervensi jangka panjang dan program multikomponen yang memuat terapi perilaku untuk menyukseskan perubahan perilaku dan menurunkan risiko kardiovaskular.Kata kunci: Edukasi, gaya hidup, pengetahuan, perilaku, risiko kardiovaskular

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Worry About Deportation and Cardiovascular Disease Risk Factors Among Adult Women: The Center for the Health Assessment of Mothers and Children of Salinas Study

Annals of Behavioral Medicine ◽

10.1093/abm/kax007 ◽

2018 ◽

Vol 52 (2) ◽

pp. 186-193 ◽

Cited By ~ 14

Author(s):

Jacqueline M Torres ◽

Julianna Deardorff ◽

Robert B Gunier ◽

Kim G Harley ◽

Abbey Alkon ◽

...

Keyword(s):

Risk Factors ◽

Body Mass Index ◽

Cardiovascular Risk ◽

Waist Circumference ◽

Body Mass ◽

Pulse Pressure ◽

Disease Risk ◽

Health Assessment ◽

Adult Women ◽

Mothers And Children

AbstractBackgroundU.S. Latinos report high levels of concern about deportation for themselves or others. No previous research has tested the link between worry about deportation and clinical measures of cardiovascular risk.PurposeWe estimate the associations between worry about deportation and clinically measured cardiovascular risk factors.MethodsData come from the Center for the Health Assessment of Mothers and Children of Salinas study. The analytic sample includes 545 Mexican-origin women.ResultsIn multivariable models, reporting a lot of worry about deportation was significantly associated with greater body mass index, greater risk of obesity, larger waist circumference, and higher pulse pressure. Reporting moderate deportation worry was significantly associated with greater risk of overweight and higher systolic blood pressure. Significant associations between worry about deportation and greater body mass index, waist circumference, and pulse pressure, respectively, held after correcting for multiple testing at p < .05.ConclusionsWorry about deportation may be an important cardiovascular risk factor for ethnic minority populations in the USA.

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Risk of cardiovascular disease after preventive salpingo-oophorectomy

International Journal of Gynecological Cancer ◽

10.1136/ijgc-2019-000856 ◽

2020 ◽

Vol 30 (5) ◽

pp. 575-582

Author(s):

Nora Johansen ◽

Serena Tonstad ◽

Astrid Helene Liavaag ◽

Randi Marie Selmer ◽

Tom Gunnar Tanbo ◽

...

Keyword(s):

Cardiovascular Disease ◽

Body Mass Index ◽

Cardiovascular Risk ◽

Waist Circumference ◽

Hormone Therapy ◽

Body Mass ◽

Assessment Tool ◽

Susceptibility Gene ◽

Breast Cancer Susceptibility Gene ◽

Historical Cohort

IntroductionBreast cancer susceptibility gene (BRCA) mutation carriers are recommended to undergo early oophorectomy to prevent ovarian cancer. Premature loss of ovarian hormones may increase the risk of cardiovascular disease. Because women with preventive oophorectomy are mainly young and healthy, they rarely undergo specialized cardiological surveillance. We compared the risk of cardiovascular disease in women after preventive oophorectomy with reference women.MethodsIn an historical cohort study, we included 134 women aged ≤52 years after preventive oophorectomy and 268 age matched premenopausal reference women, aged 52 years or less, from the general population, excluding participants with diabetes or cardiovascular disease. The Norwegian risk assessment tool (NORRISK 2) was used to estimate 10 year cardiovascular risk. This algorithm was validated in a large Norwegian population and is based on age, smoking, systolic blood pressure, total and high density lipoprotein cholesterol, antihypertensive medication, and family history of cardiovascular disease. We also examined cardiometabolic factors (levels of triglycerides and high sensitivity C reactive protein, as well as body mass index and waist circumference) not included in the NORRISK 2 calculation.ResultsMedian age in the preventive oophorectomy and reference groups were 47 (range 33–52) and 46 (31–52) years, respectively. Mean time since surgery in the preventive oophorectomy group was 4.2 years (standard deviation (SD) 2.8). Ten year cardiovascular risk was similar in women after preventive oophorectomy and reference women (mean 1.15% (SD 1.00) vs 1.25 (1.09), respectively, p=0.4). Women in the preventive oophorectomy group had a lower body mass index (24.7 kg/m2 (4.0) vs 26.2 (4.8), p=0.003) and waist circumference (86 cm vs 89, p=0.006). The overall cardiovascular risk estimation was comparable among hormone therapy users and non-users, but hormone therapy users had lower total cholesterol and waist circumference.DiscussionWomen who underwent preventive oophorectomy had a similar risk of cardiovascular disease as population based reference women, estimated according to risk factors easily measured in general practice. Cardiometabolic risks were not increased in the preventive oophorectomy group.

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