Associations between dietary inflammatory index and incidence of breast and prostate cancer: a systematic review and meta-analysis

AbstractWith depression being the psychiatric disorder incurring the largest societal costs in developed countries, there is a need to gather evidence on the role of nutrition in depression, to help develop recommendations and guide future psychiatric health care. The aim of this systematic review was to synthesize the link between diet quality, measured using a range of predefined indices, and depressive outcomes. Medline, Embase and PsychInfo were searched up to 31st May 2018 for studies that examined adherence to a healthy diet in relation to depressive symptoms or clinical depression. Where possible, estimates were pooled using random effect meta-analysis with stratification by observational study design and dietary score. A total of 20 longitudinal and 21 cross-sectional studies were included. These studies utilized an array of dietary measures, including: different measures of adherence to the Mediterranean diet, the Healthy Eating Index (HEI) and Alternative HEI (AHEI), the Dietary Approaches to Stop Hypertension, and the Dietary Inflammatory Index. The most compelling evidence was found for the Mediterranean diet and incident depression, with a combined relative risk estimate of highest vs. lowest adherence category from four longitudinal studies of 0.67 (95% CI 0.55–0.82). A lower Dietary Inflammatory Index was also associated with lower depression incidence in four longitudinal studies (relative risk 0.76; 95% CI: 0.63–0.92). There were fewer longitudinal studies using other indices, but they and cross-sectional evidence also suggest an inverse association between healthy diet and depression (e.g., relative risk 0.65; 95% CI 0.50–0.84 for HEI/AHEI). To conclude, adhering to a healthy diet, in particular a traditional Mediterranean diet, or avoiding a pro-inflammatory diet appears to confer some protection against depression in observational studies. This provides a reasonable evidence base to assess the role of dietary interventions to prevent depression. This systematic review was registered in the PROSPERO International Prospective Register of Systematic Reviews under the number CRD42017080579.

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Dietary Inflammatory Index and the Risk of Frailty Among Older Adults: A Systematic Review and Meta-Analysis

Research on Aging ◽

10.1177/0164027520948176 ◽

2020 ◽

pp. 016402752094817

Author(s):

Sajjad Moradi ◽

Amir Hadi ◽

Hamed Mohammadi ◽

Omid Asbaghi ◽

Mehdi Zobeiri ◽

...

Keyword(s):

Systematic Review ◽

Older Adults ◽

Odds Ratio ◽

Meta Analysis ◽

Ratio Analysis ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

Prospective Cohort Studies ◽

Low Bmi

A systematic review and meta-analysis was conducted to comprehensively examine the association between Dietary Inflammatory Index (DII®) score and risk of frailty. Frailty risk were available from five studies comprising 13,908 older adults. Furthermore, frailty related parameters were extacted from two studies with 7,539 individuals. A pooled adjusted odds ratio analysis indicated that there was an association between DII® score and frailty risk (OR = 1.24, 95%CI: 1.6–1.33, P < 0.001, I2 = 0.0%). The results of frailty related parameters demonstrated that DII® score was associated with weakness risk (OR = 1.12, 95%CI: 1.05–1.19, P = 0.014, I2 = 0.0%), but not other frailty-related parameters including exhaustion, low BMI or low physical activity. The results of this meta-analysis suggest that older adults who exhibit higher DII® scores have an increased frailty risk. Further prospective cohort studies with longer follow-up periods, are needed to support this possible association between DII® score and frailty risk.

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Dietary inflammatory index and the risk of prostate cancer: a dose-response meta-analysis

European Journal of Clinical Nutrition ◽

10.1038/s41430-019-0500-3 ◽

2019 ◽

Vol 74 (7) ◽

pp. 1001-1008 ◽

Cited By ~ 2

Author(s):

Yi Zhu ◽

Qinchen Li ◽

Xin Xu

Keyword(s):

Prostate Cancer ◽

Dose Response ◽

Meta Analysis ◽

Dietary Inflammatory Index ◽

Inflammatory Index

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Associations of dietary inflammatory index with metabolic syndrome and its components: a systematic review and meta-analysis

Public Health Nutrition ◽

10.1017/s1368980021000288 ◽

2021 ◽

pp. 1-8

Author(s):

Qian Yi ◽

Xue Li ◽

Yazhou He ◽

Wei Xia ◽

Jing Shao ◽

...

Keyword(s):

Systematic Review ◽

Metabolic Syndrome ◽

Meta Analysis ◽

Hdl Cholesterol ◽

Dietary Inflammatory Index ◽

Dietary Interventions ◽

Cross Sectional ◽

Inflammatory Index ◽

Search Terms ◽

Low Hdl

Abstract Objective: Inflammation has been suggested to play an important role in the development and progression of metabolic syndrome (MetS). Dietary inflammatory index (DII), a measurement of inflammatory potential in diets, was suggested to be associated with MetS. The aim of this systematic review and meta-analysis was to establish the associations of DII with MetS and its components based on available observational studies. Design: Systematic review and meta-analysis. Setting: A comprehensive literature search of studies that assessed the associations between DII and MetS was conducted in PubMed, Medline and Embase, using a combination of search terms relating to DII and MetS. Participants: Eighteen articles were eligible, of which fourteen were cross-sectional and four were cohort in design. Results: Results from the random effects meta-analysis showed significantly positive associations of higher DII (top v. bottom quartiles) with MetS (OR: 1·23 (95 % CI 1·10, 1·37)), abdominal obesity (OR: 1·15 (95 % CI 1·02, 1·29)), high blood pressure (OR: 1·17 (95 % CI 1·07, 1·29)), hyperglycaemia (OR: 1·18 (95 % CI 1·05, 1·33)) and hypertriacylglycerolaemia (OR: 1·17 (95 % CI 1·07, 1·28)). The effects of summary OR became stronger when analyses were restricted to cohorts, studies that adjudged for covariates (including BMI, physical activity and total energy intake). Conclusions: Higher DII, representing pro-inflammatory diet, is associated with higher odds of MetS and its components, except for low HDL-cholesterol. The findings prompt dietary interventions for preventing MetS from the aspect of inflammation.

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Dietary Inflammatory Index and its Association with the Risk of Cardiovascular Diseases, Metabolic Syndrome, and Mortality: A Systematic Review and Meta-Analysis

Hormone and Metabolic Research ◽

10.1055/a-0596-8204 ◽

2018 ◽

Vol 50 (05) ◽

pp. 345-358 ◽

Cited By ~ 30

Author(s):

Nazli Namazi ◽

Bagher Larijani ◽

Leila Azadbakht

Keyword(s):

Systematic Review ◽

Metabolic Syndrome ◽

Meta Analysis ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

All Cause Mortality ◽

Diet Versus ◽

Different Populations ◽

Anti Inflammatory ◽

Cvd Mortality

AbstractFindings from previous studies on the association between the Dietary Inflammatory Index (DII) and the risk of chronic diseases and mortality have been inconsistent. We aimed to summarize studies on the association of the DII and the risk for cardiovascular disease (CVD), metabolic syndrome (MetS), and mortality in a systematic review and meta-analysis. We performed a systematic search in PubMed/Medline, Web of Knowledge, and Scopus databases for relevant studies written in English and published until 31 December 2017. Studies that reported the relative risk (RR), odd ratio (OR) or hazard ratio (HR) for the most pro-inflammatory versus the most anti-inflammatory diets were included. Finally, 17 studies [CVD (n=6), MetS (n=5), mortality (n=6)] were included for systematic review and meta-analysis. Findings indicated a trend toward a positive relationship between the DII and the risk for CVD (pooled RR: 1.35; 95% CI: 1.13, 1.60; I2: 28.6%, p=0.21), all-cause mortality (pooled HR: 1.21; 95% CI: 1.09, 1.35; I2: 72.6%, p=0.003), CVD mortality (pooled HR: 1.30, 95% CI: 1.07, 1.57; I2: 74.0%, p=0.009) and cancer mortality (pooled HR: 1.28; 95% CI: 1.07, 1.53; I2: 62.5%, p=0.03). However, no significant association was found between the DII and the risk for MetS (pooled RR: 1.01; 95% CI: 0.82, 1.24; I2: 32.6%, p=0.20). Although in the current meta-analysis the most pro-inflammatory diet versus the most anti-inflammatory diet was not associated with the risk of MetS, we observed a substantial association between the DII and the risk for CVD and all types of mortality. However, further cohort studies in different populations are needed to clarify this association.

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Dietary inflammatory index significantly affects lipids profile among adults: An updated systematic review and meta-analysis

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000688 ◽

2020 ◽

pp. 1-17

Author(s):

Mahdi Vajdi ◽

Mahdieh Abbasalizad Farhangi ◽

Mahsa Mahmoudi-Nezhad

Keyword(s):

Systematic Review ◽

Serum Lipids ◽

Meta Analysis ◽

Density Lipoprotein ◽

Case Control ◽

Lipoprotein Cholesterol ◽

Dietary Inflammatory Index ◽

Cross Sectional ◽

Inflammatory Index ◽

The Relationship

Abstract. Background: The available data on the relationship between dietary inflammatory index (DII®) and serum lipids are controversial. This systematic review and meta-analysis aimed to investigate the relationship between DII® and serum lipids, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) in general populations. Methods: PubMed, Web of Science, SCOPUS, and Cochrane electronic databases were systematically searched from inception to December 2019. Case-control, cohort or cross-sectional studies that evaluated the relationship between DII® and serum lipids were included. The random-effects model was applied to evaluate the pooled weighted mean difference (WMD) and 95% confidence intervals (CI). Results: In total, twenty-four cross-sectional and one case-control studies with a total sample size of 129,759 were included in the meta-analysis. The pooled results showed that the highest category of DII® was associated with 5.16 mg/dl increase in TC (Pooled WMD: 5.16; 95% CI: 0.58–9.73, p = 0.02) and 3.99 mg/dl increase in LDL-C (Pooled WMD: 3.99; 95% CI: 1.16–6.81, p = 0.006). However, no significant association between DII® scores, HDL-C and TG was found. In subgroup analysis, the geographical region, gender, and dietary assessment methods were potent sources of heterogeneity. Conclusion: This study showed that a higher level of DII® was associated with higher levels of TC and LDL-C in apparently healthy populations. Since the included studies had observational designs, therefore, no conclusion of causality was possible. More studies with interventional designs are required to elucidate the causality of the observed association between DII® and the risk of abnormal lipid profile.

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