scholarly journals Susceptibility profile of a Brazilian yeast stock collection of Candida species isolated from subjects with Candida-associated denture stomatitis with or without diabetes

2013 ◽  
Vol 116 (5) ◽  
pp. 562-569 ◽  
Author(s):  
Paula Volpato Sanitá ◽  
Ewerton Garcia de Oliveira Mima ◽  
Ana Cláudia Pavarina ◽  
Janaina Habib Jorge ◽  
Ana Lúcia Machado ◽  
...  
Keyword(s):  
Candida Species ◽  
Denture Stomatitis

scholarly journals Denture Stomatitis: Report of a Case with Rarely Used Treatment Modality and Review of Literature

2020 ◽  
Vol 4 (5) ◽  
pp. 116-119
Author(s):  
Parul Uppal Malhotra ◽  
Neera Ohri ◽  
Yagyeshwar Malhotra ◽  
Anindita Mallik
Keyword(s):  
Candida Albicans ◽  
Candida Species ◽  
Fungal Infections ◽  
Bacterial Colonization ◽  
Oral Candidiasis ◽  
Clinical Signs ◽  
Fungal Growth ◽  
Dimorphic Fungus ◽  
Denture Stomatitis ◽  
Microbial Invasion

Candida albicans is the most common Candida species isolated from the oral cavity both in healthy and diseased. Candida albicans is a dimorphic fungus existing both in blastopore phase (yeast phase) and the hyphal or mycelial phase. Although these organisms typically colonize mucocutaneous surfaces, the latter can be portals of entry into deeper tissues when host defences are compromised. Denture stomatitis is a common form of oral candidiasis that manifests as a diffuse inflammation of the maxillary denture bearing areas & is associated with angular cheilitis. At least 70% of individuals with clinical signs of denture stomatitis exhibit fungal growth & these conditions most likely result from yeast colonization of the oral mucosa combined with Bacterial colonization. Candida species act as an endogenous infecting agent on tissue predisposed by chronic trauma to microbial invasion. At one time, oral fungal infections were rare findings in general dentist's office. They were more commonly seen in hospitalized and severely debilitated patients. However with enhanced medical and pharmaceutical technology, increasing numbers of ambulatory immunosuppressed individuals with oral fungal infections are seeking out general dentists for diagnosis and treatment of these lesions.

Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis

2014 ◽  
Vol 24 (4) ◽  
pp. 296-302 ◽  
Author(s):  
Ana Carolina Loureiro Gama Mota ◽  
Ricardo Dias de Castro ◽  
Julyana de Araújo Oliveira ◽  
Edeltrudes de Oliveira Lima
Keyword(s):  
Antifungal Activity ◽  
Candida Species ◽  
Denture Stomatitis ◽  
Apple Cider

scholarly journals Original article. The use of essential oils based antiseptic solution in the treatment of denture stomatitis

2017 ◽  
Vol 64 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Ognjenka Janjić-Pavlović ◽  
Ivica Stančić ◽  
Smiljka Cicmil ◽  
Zorica Stojanović ◽  
Jelena Lečić ◽  
...  
Keyword(s):  
Candida Species ◽  
Local Therapy ◽  
Mucosal Inflammation ◽  
Control Group ◽  
Denture Base ◽  
Denture Stomatitis ◽  
Antiseptic Solution ◽  
The Difference ◽  
Fungi Infection ◽  
Palatal Mucosa

Summary Introduction Local therapy of denture stomatitis (DS) associated with Candida species fungi infection usually involves the application of nystatin and miconazole. Due to the fact that these drugs may be less efficient against biofilm and possible resistance development, a new approach in the treatment includes the use of antiseptic agents. The aim of the study was to compare clinical and microbiological therapeutic outcomes of antiseptic solution Listerine® and Daktanol® antifungal oral gel in the treatment of DS associated with Candida species fungi. Material and Methods The study included 30 patients affected by DS, divided into the two treatment groups, control group (n=15) treated by Daktanol® gel and experimental group (n=15) treated by the antiseptic solution Listerine®. Successful treatment was evaluated based on palatal mucosa inflammation reduction classified according to the Newton classification and the difference in the number of fungal colony- forming units (CFU) isolated by smears before and after the treatment that lasted 14 days. Results Reduction in inflammation intensity and fungal CFU number on palatal mucosa (p<0,01) as well as on denture base (p<0,01) were observed in both groups of subjects after the treatment. Conclusion Antiseptic solution Listerine® and Daktanol® antifungal gel both reduced palatal mucosal inflammation and CFU number of fungi in mouth without significant differences among them. CFU number of fungi isolated from denture base was significantly lower after the treatment with Listerine® (p<0.05).

Distribution and phospholipase activity of Candida species in different denture stomatitis types

2006 ◽  
Vol 162 (6) ◽  
pp. 389-394 ◽  
Author(s):  
Birsay Gümrü ◽  
Tanju Kadir ◽  
Banu Uygun-Can ◽  
Semih Özbayrak
Keyword(s):  
Candida Species ◽  
Phospholipase Activity ◽  
Denture Stomatitis

scholarly journals SCREENING OF SELECTED PLANT ESSENTIAL OILS FOR THEIR ANTIFUNGAL ACTIVITY AGAINST CANDIDA SPECIES ISOLATED FROM DENTURE STOMATITIS PATIENTS

2014 ◽  
Vol 04 (01) ◽  
pp. 046-051
Author(s):  
Vinaya Bhat ◽  
S.M. Sharma ◽  
Veena Shetty ◽  
C.S. Shastry ◽  
Vaman Rao ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Essential Oils ◽  
Candida Species ◽  
Antifungal Agents ◽  
Complete Denture ◽  
Synergistic Activity ◽  
Clove Oil ◽  
Origanum Vulgare ◽  
Denture Stomatitis

Abstract: Background: Many efforts have been made to discover new antimicrobial compounds from various sources such as micro-organisms, animals and plants. Use of herbal medicines has a long history in Asian population in treating different ailments. Many plants have been found to have properties like antibacterial, antifungal and antioxidant activities.In a complete denture wearer, due to either local or systemic factors, denture stomatitis has been found to a have high prevalence. In such patients, higher incidence of Candida infection and increased levels of Candida spp. also have been identified. Existing antifungal agents like Nystatin & Fluconazole have been found to have toxic effects on long term application and chances of development of drug resistance is high. Medicinal plants have been used to inhibit growth and development of fungal infection from Candida isolated from sites other than oral cavity. Objectives: To evaluate the antifungal activity of some of the medicinal essential oils against oral isolates of Candida obtained from denture wearing patients identified through a survey. Materials and Methods: The oral isolates of Candida species were collected after conducting a survey of complete denture wearers, wearing the denture for at least more than a year. The speciation of the organism was done after identifying it from the specimens. It was confirmed with the help of germ tube test, other biochemical tests and chlamydospore formation tests. A lab isolate also was included in the study. The essential oils of different herbs were extracted using hydro distillation methods. The antifungal activity of these oils was tested and compared with antifungal activity of Nystatin and fluconazole using modified Kirby-Baeur method. The inhibition zones of different oils were measured and compared among themselves against all the clinical isolates and the lab isolate. Results: About 55 complete denture wearing patients have been surveyed and among them 27 have been found to be positive for Candida-associated denture stomatitis. Among the Candida species, Candida albicans was more prevalent followed by C. tropicalis and C. glabrata.Among the test essential oils, Origanum vulgare (stored & fresh) and clove oil gave positive results against all isolates. The fresh samples gave better results than the stored and all three oils showed more antifungal activity than Nystatin & fluconazole. Interpretation: The candida-associated denture stomatitis is prevalent in patients who are wearing denture prosthesis for more than a year.Candida albicans is the most prevalent causative species followed by C. tropicalis and C. glabrata.Origanum vulgare and clove oil are potent antifungal agents against oral species of Candida. They can be either used separately or their synergistic activity could be explored against denture stomatitis.

scholarly journals Efficacy of Camellia sinensis extract against Candida species in patients with denture stomatitis

2018 ◽  
Author(s):  
Anahita Ghorbani ◽  
Ashena Sadrzadeh ◽  
Emran Habibi ◽  
Kosar Dadgar ◽  
Jafar Akbari ◽  
...  
Keyword(s):  
Green Tea ◽  
Camellia Sinensis ◽  
Candida Species ◽  
Study Groups ◽  
Common Species ◽  
Lesion Size ◽  
Denture Stomatitis ◽  
Significant Difference ◽  
Before And After ◽  
Effective Drugs

  Background and Purpose: Denture stomatitis is a chronic inflammation disease of the oral mucosa, which is specified by erythematous lesions mainly in the upper palate. Nystatin as a polyene, a class of antifungal agents, is one of the effective drugs to treat denture stomatitis. Considering the expansion of utilizing herbal drugs to cure many kinds of diseases, the present study was conducted to investigate the effects of Camellia sinensis (green tea), which has the most chemical and influence similarity with nystatin, against denture stomatitis. Materials and Methods: This study was conducted on 22 patients with a positive mycological evidence for denture stomatitis caused by Candida species. The study population was divided into two groups, namely green tea and nystatin, receiving green tea mouthwash 0.5% and nystatin suspension 100,000 U/ml, respectively. The lesion size and number of yeast colonies were measured before and after the treatment. Results: According to the results, both groups showed reduced lesion size, clinical improvement, and significant reduction of Candida colony count in both group of patients were showedafter the therapeutic. Based on the results of polymerase chain reaction, Candida albicans was the most common species isolated from denture stomatitis. There was no significant difference between the two study groups in terms of Candida species distribution (P=0.700). Conclusion: Green tea demonstrated a comparable anti-Candida activity with regard to nystatin; therefore, it could be recommended as an alternative treatment.

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