PCA-based real-time single-photon 3D imaging method

2021 ◽  
pp. 127777
Author(s):  
Yao Duan ◽  
Chuanchuan Yang ◽  
Hongbin Li
Keyword(s):  
Real Time ◽  
3D Imaging ◽  
Single Photon ◽  
Imaging Method

Real time processing enables fast 3D imaging at single photon level

2008 ◽  
Author(s):  
Ivelin Bakalski ◽  
Joao Pereira Do Carmo ◽  
Stephen Bellis ◽  
Robert Bond ◽  
Martin Himphries ◽  
...  
Keyword(s):  
Real Time ◽  
3D Imaging ◽  
Single Photon ◽  
Real Time Processing ◽  
Time Processing

scholarly journals Real-time imaging of cellular forces using optical interference

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Andrew T. Meek ◽  
Nils M. Kronenberg ◽  
Andrew Morton ◽  
Philipp Liehm ◽  
Jan Murawski ◽  
...  
Keyword(s):  
Cell Culture ◽  
Real Time ◽  
High Throughput ◽  
Mechanical Activity ◽  
Dynamic Processes ◽  
Imaging Method ◽  
Neonatal Cardiomyocytes ◽  
A Cell ◽  
Cellular Forces ◽  
Time Acquisition

AbstractImportant dynamic processes in mechanobiology remain elusive due to a lack of tools to image the small cellular forces at play with sufficient speed and throughput. Here, we introduce a fast, interference-based force imaging method that uses the illumination of an elastic deformable microcavity with two rapidly alternating wavelengths to map forces. We show real-time acquisition and processing of data, obtain images of mechanical activity while scanning across a cell culture, and investigate sub-second fluctuations of the piconewton forces exerted by macrophage podosomes. We also demonstrate force imaging of beating neonatal cardiomyocytes at 100 fps which reveals mechanical aspects of spontaneous oscillatory contraction waves in between the main contraction cycles. These examples illustrate the wider potential of our technique for monitoring cellular forces with high throughput and excellent temporal resolution.

Real-Time 3D Imaging using an Air-Coupled Ultrasonic Phased-Array

2020 ◽  
pp. 1-1 ◽  
Author(s):  
Gianni Allevato ◽  
Jan Hinrichs ◽  
Matthias Rutsch ◽  
Jan Adler ◽  
Axel Jager ◽  
...  
Keyword(s):  
Real Time ◽  
3D Imaging ◽  
Phased Array ◽  
Ultrasonic Phased Array

scholarly journals Design of a Real-Time Breakdown Voltage and On-Chip Temperature Monitoring System for Single Photon Avalanche Diodes

Electronics ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 25
Author(s):  
Shijie Deng ◽  
Alan P. Morrison ◽  
Yong Guo ◽  
Chuanxin Teng ◽  
Ming Chen ◽  
...  
Keyword(s):  
Real Time ◽  
Breakdown Voltage ◽  
Count Rate ◽  
Single Photon ◽  
Photon Counting ◽  
Temperature Monitoring ◽  
Dark Count ◽  
Chip Temperature ◽  
Avalanche Diodes ◽  
On Chip

The design and implementation of a real-time breakdown voltage and on-chip temperature monitoring system for single photon avalanche diodes (SPADs) is described in this work. In the system, an on-chip shaded (active area of the detector covered by a metal layer) SPAD is used to provide a dark count rate for the breakdown voltage and temperature calculation. A bias circuit was designed to provide a bias voltage scanning for the shaded SPAD. A microcontroller records the pulses from the anode of the shaded SPAD and calculates its real-time dark count rate. An algorithm was developed for the microcontroller to calculate the SPAD’s breakdown voltage and the on-chip temperature in real time. Experimental results show that the system is capable of measuring the SPAD’s breakdown voltage with a mismatch of less than 1.2%. Results also show that the system can provide real-time on-chip temperature monitoring for the range of −10 to 50 °C with errors of less than 1.7 °C. The system proposed can be used for the real-time SPAD’s breakdown voltage and temperature estimation for dual-SPADs or SPAD arrays chip where identical detectors are fabricated on the same chip and one or more dummy SPADs are shaded. With the breakdown voltage and the on-chip temperature monitoring, intelligent control logic can be developed to optimize the performance of the SPAD-based photon counting system by adjusting the parameters such as excess bias voltage and dead-time. This is particularly useful for SPAD photon counting systems used in complex working environments such as the applications in 3D LIDAR imaging for geodesy, geology, geomorphology, forestry, atmospheric physics and autonomous vehicles.

Real-time 3D Imaging and Velocity Measurement of Two-phase Flow using a Twin-plane ECT Sensor

2021 ◽  
pp. 1-1
Author(s):  
Shijie Sun ◽  
Xupeng Lu ◽  
Lijun Xu ◽  
Zhang Cao ◽  
Jiangtao Sun ◽  
...  
Keyword(s):  
Real Time ◽  
Velocity Measurement ◽  
3D Imaging ◽  
Two Phase Flow ◽  
Twin Plane ◽  
Phase Flow ◽  
Two Phase

scholarly journals Probe-based confocal laser endomicroscopy and Barrett's esophagus – just a scientific toy or significant improvement in diagnosis?

2021 ◽  
Author(s):  
Luka Vranić ◽  
Tin Nadarević ◽  
Davor Štimac
Keyword(s):  
Diagnostic Accuracy ◽  
Real Time ◽  
Barrett’S Esophagus ◽  
Predictive Value ◽  
Barrett's Esophagus ◽  
High Reliability ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Imaging Method ◽  
Increased Risk

Background: Barrett’s esophagus (BE) requires surveillance to identify potential neoplasia at early stage. Standard surveillance regimen includes random four-quadrant biopsies by Seattle protocol. Main limitations of random biopsies are high risk of sampling error, difficulties in histology interpretation, common inadequate classification of pathohistological changes, increased risk of bleeding and time necessary to acquire the final diagnosis. Probe-based confocal laser endomicroscopy (pCLE) has emerged as a potential tool with an aim to overcome these obvious limitations. Summary: pCLE represents real-time microscopic imaging method that offers evaluation of epithelial and subepithelial structures with 1000-fold magnification. In theory, pCLE has potential to eliminate the need for biopsy in BE patient. The main advantages would be real-time diagnosis and decision making, greater diagnostic accuracy and to evaluate larger area compared to random biopsies. Clinical pCLE studies in esophagus show high diagnostic accuracy and its high negative predictive value offers high reliability and confidence to exclude dysplastic and neoplastic lesions. However, it still cannot replace histopathology due to lower positive predictive value and sensitivity. Key messages: Despite promising results, its role in routine use in patients with Barrett’s esophagus remains questionable primarily due to lack of well-organized double-blind randomized trials.

Real-time processing framework of common-aperture active and passive hyperspectral 3D imaging

2021 ◽  
Vol 50 (2) ◽  
pp. 20200249-20200249
Author(s):  
贺文静 Wenjing He ◽  
胡坚 Jian Hu ◽  
陈育伟 Yuwei Chen ◽  
潘苗苗 Miaomiao Pan ◽  
朱运维 Yunwei Zhu ◽  
...  
Keyword(s):  
Real Time ◽  
3D Imaging ◽  
Real Time Processing ◽  
Time Processing ◽  
Processing Framework
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