Associations between weather conditions and clinical symptoms in patients with hip osteoarthritis: A 2-year cohort study

Pain ◽  
2014 ◽  
Vol 155 (4) ◽  
pp. 808-813 ◽  
Author(s):  
Desirée M.J. Dorleijn ◽  
Pim A.J. Luijsterburg ◽  
Alex Burdorf ◽  
Rianne M. Rozendaal ◽  
Jan A.N. Verhaar ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Symptoms ◽  
Hip Osteoarthritis ◽  
Weather Conditions

scholarly journals Association between biochemical cartilage markers and clinical symptoms in patients with hip osteoarthritis: cohort study with 2-year follow-up

2015 ◽  
Vol 23 (1) ◽  
pp. 57-62 ◽  
Author(s):  
D.M.J. Dorleijn ◽  
P.A.J. Luijsterburg ◽  
A.C. Bay-Jensen ◽  
A.S. Siebuhr ◽  
M.A. Karsdal ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Symptoms ◽  
Hip Osteoarthritis

scholarly journals Association between biochemical cartilage markers and clinical symptoms in patients with hip osteoarthritis: cohort study with two-year follow-up

2014 ◽  
Vol 22 ◽  
pp. S75-S76
Author(s):  
D.M. Dorleijn ◽  
P.A. Luijsterburg ◽  
A.C. Bay-Jensen ◽  
A.S. Siebuhr ◽  
M. Karsdal ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Symptoms ◽  
Hip Osteoarthritis

scholarly journals Resuming professional football (soccer) during the COVID-19 pandemic in a country with high infection rates: a prospective cohort study

2021 ◽  
pp. bjsports-2020-103724
Author(s):  
Yorck Olaf Schumacher ◽  
Montassar Tabben ◽  
Khalid Hassoun ◽  
Asmaa Al Marwani ◽  
Ibrahim Al Hussein ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Preventive Measures ◽  
Clinical Symptoms ◽  
Severe Illness ◽  
Football Players ◽  
Professional Football ◽  
Infection Rates ◽  
High Infection

ObjectivesThe risk of viral transmission associated with contact sports such as football (soccer) during the COVID-19 pandemic is unknown. The aim of this study was to describe the infective and immune status of professional football players, team staff and league officials over a truncated football season resumed at the height of the COVID-19 pandemic in a country with high infection rates and to investigate the clinical symptoms related to COVID-19 infection in professional football players.MethodsProspective cohort study of 1337 football players, staff and officials during a truncated football season (9 weeks) with a tailored infection control programme based on preventive measures and regular SARS-CoV-2 PCR swab testing (every 3–5 days) combined with serology testing for immunity (every 4 weeks). Clinical symptoms in positive participants were recorded using a 26-item, Likert-Scale-based scoring system.ResultsDuring the study period, 85 subjects returned positive (cycle threshold (cT) ≤30) or reactive (30<cT<40) PCR tests, of which 36 were players. The infection rate was consistent with that of the general population during the same time period. More than half of infected subjects were asymptomatic, and the remaining had only mild symptoms with no one requiring hospitalisation. Symptom severity was associated with lower cT values. Social contacts and family were the most common sources of infection, and no infection could be traced to training or matches. Of the 36 infected players, 15 presented positive serology during the study period.ConclusionFootball played outdoors involving close contact between athletes represents a limited risk for SARS-CoV-2 infection and severe illness when preventive measures are in place.

scholarly journals Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study

2008 ◽  
Vol 68 (4) ◽  
pp. 490-496 ◽  
Author(s):  
L S Lohmander ◽  
M Gerhardsson de Verdier ◽  
J Rollof ◽  
P M Nilsson ◽  
G Engström
Keyword(s):  
Cohort Study ◽  
Waist Circumference ◽  
Knee Osteoarthritis ◽  
Body Mass ◽  
Hip Osteoarthritis ◽  
Population Based ◽  
Normal Weight ◽  
Men And Women ◽  
Relative Risks ◽  
Percentage Of Body Fat

Objective:To determine in a prospective population-based cohort study relationships between different measures of body mass and the incidence of severe knee and hip osteoarthritis defined as arthroplasty of knee or hip due to osteoarthritis.Materials and methods:Body mass index (BMI), waist circumference, waist–hip ratio (WHR), weight and percentage of body fat (BF%) were measured at baseline in 11 026 men and 16 934 women from the general population. The incidence of osteoarthritis over 11 years was monitored by linkage with the Swedish hospital discharge register.Results:471 individuals had knee osteoarthritis and 551 had hip osteoarthritis. After adjustment for age, sex, smoking and physical activity, the relative risks (RR) of knee osteoarthritis (fourth vs first quartile) were 8.1 (95% CI 5.3 to 12.4) for BMI, 6.7 (4.5 to 9.9) for waist circumference, 6.5 (4.6 to 9.43) for weight, 3.6 (2.6 to 5.0) for BF% and 2.2 (1.7 to 3.0) for WHR. Corresponding RR for hip osteoarthritis were 2.6 (2.0 to 3.4) for BMI, 3.0 (2.3 to 4.0) for weight, 2.5 (1.9 to 3.3) for waist, 1.3 (0.99 to 1.6) for WHR and 1.5 (1.2 to 2.0) for BF%.Conclusion:All measures of overweight were associated with the incidence of knee osteoarthritis, with the strongest relative risk gradient observed for BMI. The incidence of hip osteoarthritis showed smaller but significant differences between normal weight and obesity. Our results support a major link between overweight and biomechanics in increasing the risk of knee and hip osteoarthritis in men and women.

scholarly journals Is the development of Modic changes associated with clinical symptoms? A 14-month cohort study with MRI

2012 ◽  
Vol 21 (11) ◽  
pp. 2271-2279 ◽  
Author(s):  
Rikke K. Jensen ◽  
Charlotte Leboeuf-Yde ◽  
Niels Wedderkopp ◽  
Joan S. Sorensen ◽  
Tue S. Jensen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Symptoms ◽  
Modic Changes

scholarly journals Gejala Klinis dan Pemeriksaan Penunjang pada Neonatus Terinfeksi COVID-19

e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Jason Rampengan ◽  
Johnny Rompis ◽  
Valentine Umboh
Keyword(s):  
Cohort Study ◽  
Case Report ◽  
Literature Review ◽  
Observational Study ◽  
Ct Scan ◽  
Clinical Symptoms ◽  
Ground Glass Opacity ◽  
Google Scholar ◽  
Ground Glass ◽  
Laboratory Examinations

Abstract: COVID-19 is spreading at an extremely rapid rate and can affect all age groups, albeit, information about clinical symptoms and laboratory examinations of COVID-19 I in neonates is still quite limited. This study was aimed to determine the clinical symptoms, radiographic examinations especially CT-scans, and laboratory tests that could appear in neonates suffering from COVID-19. This was a literature review study using three databases, namely Pubmed, Clinical Key, and Google Scholar. The keywords used were Covid-19 / SARS-CoV-2 AND Neonatus AND sign and symptoms AND laboratory. The selection based on inclusion and exclusion criteria, obtained 15 case report studies, three retrospective studies, one observational study, and one cohort study. The review revealed that the most frequent clinical features that appeared were fever (54.8%), dyspnoea (35.4%), and cough (29%). Meanwhile, for CT-Scan radiographs, there were 14 of 31 neonates (45.2%) did not show any abnormalities or normal. The most frequent abnormal image was ground glass opacity (GGO) (29%). Among laboratory examinations, lymphopenia was the most common abnormality (32.2%). Moreover, leukocytosis, leukopenia, thrombocytopenia, increased PCT, AST, etc. could also occur. Of all the reviewed literatures, there were no death cases of neonates died due to COVID-19. In conclusion, fever, dyspnea, cough, and lymphopenia are the most common findings as well as GGO in the CT-Scan radiograph.Keywords: COVID-19, neonates Abstrak: COVID-19 menyebar dengan sangat pesat dan dapat menjangkiti semua kelompok usia namun informasi mengenai gejala klinis dan pemeriksaan laboratorium terhadap kelompok neonatus masih terbatas. Penelitian ini bertujuan untuk mengetahui gambaran klinis, pemeriksaan radiografi khususnya CT-Scan, dan pemeriksaan laboratorium yang bisa muncul pada neonatus dengan COVID-19. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu Pubmed, Clinical Key, dan Google Scholar. Kata kunci yang digunakan yaitu Covid-19/ SARS-CoV-2 AND Neonatus AND sign and symptom AND laboratory. Hasil seleksi berdasarkan kriteria inklusi dan ekslusi mendapatkan 15 penelitian case report, tiga retrospective study, satu observational study, dan satu cohort study. Hasil kajian menunjukkan bahwa gambaran klinis yang paling sering muncul ialah demam (54,8%), sesak (35,4%), dan batuk (29%). Pemeriksaan radiografi CT-Scan, neonatus yang tidak menunjukkan kelainan (normal) terdapat pada 14 dari 31 neonatus diamati (45,2%), sedangkan kelainan yang sering muncul ialah ground glass opacity/GGO (29%). Pada pemeriksaan laboratorium, limfopenia merupakan kelainan tersering (32,2%), sedangkan leukositosis, leukopenia, trombositopenia, peningkatan PCT, AST, dll juga bisa terjadi. Dari semua literatur yang dikaji, tidak ditemukan kasus kematian neonatus akibat COVID-19. Simpulan penelitian ini ialah gambaran klinis yang paling sering muncul pada neonatus ialah demam, sesak, dan batuk, limfopenia, dan GGO pada CT-Scan.Kata kunci: COVID-19, neonatus

scholarly journals How different domains of quality of life are associated with latent dimensions of mental health measured by GHQ-12

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Fatemeh Nouri ◽  
Awat Feizi ◽  
Hamidreza Roohafza ◽  
Masoumeh Sadeghi ◽  
Nizal Sarrafzadegan
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Cohort Study ◽  
Physical Health ◽  
Social Relationships ◽  
Rural Areas ◽  
Clinical Symptoms ◽  
Short Form ◽  
Environmental Condition

Abstract Background and objectives A short form of the General Health Questionnaire (GHQ-12) is a useful screening instrument for assessing mental health. Furthermore, Quality of life (QoL) is a critical treatment outcome in many clinical and health care research settings. This study aimed to reassess the dimensionality of GHQ-12 using Multidimensional Graded Response Model (MGRM) and evaluate how its extracted dimensions are associated with the QoL's domains. Methods Isfahan Cohort Study 2 (ICS2) is a population-based, ongoing prospective cohort study among adults aged 35 years and older who were free of cardiovascular diseases (CVDs) at the beginning of the study in 2013. A total of 1316 participants, all living in urban and rural areas of Isfahan and Najafabad, Iran was completed the GHQ-12 and WHO QoL-brief version at baseline. Five competing MGRMs with different latent structures were specified for GHQ-12. Factor scores derived from the best fitted model were used to associate with various domains of QoL. Results: The Three-Dimensional model for GHQ-12 was the best-fitted model explaining the Social Function (SF), Self Confidence (SC), and Anxiety/Depression (A/D) as three correlated yet different latent dimensions of mental health. Our findings in full adjusted multivariate regression models showed that a one-SD increase in dimensions of SC and SF was associated with a 38- to 48%-SD and 27- to 38%-SD increase in the domains scores of QoL, respectively. Moreover, for each one‐SD increase in score of A/D dimension, the domains scores of QoL decreased by 29- to 40%-SD. The highest to the lowest standardized coefficients for all latent dimensions of mental health were respectively related to the psychological, physical health, social relationships, and environmental condition domains of QoL. Furthermore, SC, A/D, and SF dimensions of GHQ-12 showed the highest to the lowest degree of association with all domains of QoL. Conclusions Our findings confirm that the GHQ-12 as a multidimensional rather than unitary instrument measures distinct dimensions of mental health. Furthermore, all aspects of QoL changed when the intensity of latent dimensions of mental health increased. Moreover, the psychological domain of QoL is the most affected by all latent dimensions of mental health, followed by physical health, social relationships, and environmental condition domains. It seems that in an attempt to full recovery as assessed by improved QoL outcomes, treatment of clinical symptoms may not be sufficient. Identifying and differentiating the structures of mental health in each community as well as implementing intervention programs aimed at focusing on specific dimensions may help in the prevention of further deterioration of mental health and improved QoL in the community.

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